Neuroplasticity & Repair Lab

Philip J Horner, PhD
Professor of Neuroregeneration, Academic Institute
Scientific Director, Center for Neuroregeneration
Full Member, Research Institute
Department of Neurosurgery
Neurological Institute
Regenerative Medicine Program
Houston Methodist
Weill Cornell Medical College

Our mission is to generate therapies for people who suffer from chronic paralysis and neurologic loss due to devastating injury, stroke or degenerative disease. The Horner lab specializes in neural stem cell biology, neural activity and stimulation, robotics, cell growth, myelin and the genetic regulation of plasticity. Signature projects include a focus on restoration of locomotor and sensory function through neural stimulation and promotion of innate regenerative capacity through cell and gene therapy. Researchers have also harnessed the tools of cell engineering to create human neural circuits within experimental microenvironments to better model disease and produce neural replacement parts for repair of the brain and spinal cord. 

Active research initiatives include neural regeneration strategies to address recovery from:
  • Spinal cord injury
  • Stroke
  • Head Injury
  • Glaucoma
  • Motor/cognitive decline associated with aging

The Horner Lab for Neuroplasticity and Repair Research receives multiple grants for studies on regeneration after spinal cord injury