Publications


Mitochondria-targeted oligomeric a-synuclein induces TOM40 degradation and mitochondrial dysfunction in Parkinson’s disease and parkinsonism-dementia of Guam
Vasquez, V, Kodavati, M, Mitra, J, Vedula, I, Hamilton, DJ, Garruto, RM, Rao, KS & Hegde, ML 2024, , Cell Death and Disease, vol. 15, no. 12, 914. https://doi.org/10.1038/s41419-024-07258-5

FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease
Kodavati, M, Wang, H, Guo, W, Mitra, J, Hegde, PM, Provasek, V, Rao, VHM, Vedula, I, Zhang, A, Mitra, S, Tomkinson, AE, Hamilton, DJ, Van Den Bosch, L & Hegde, ML 2024, , Nature Communications, vol. 15, no. 1, 2156. https://doi.org/10.1038/s41467-024-45978-6

FUS unveiled in mitochondrial DNA repair and targeted ligase-1 expression rescues repair-defects in FUS-linked motor neuron disease
Kodavati, M, Wang, H, Guo, W, Mitra, J, Hegde, PM, Provasek, VE, Maloji Rao, VH, Vedula, I, Zhang, A, Mitra, S, Tomkinson, AE, Hamilton, DJ, Van Den Bosch, L & Hegde, M 2024, , Nat Commun, vol. 15, no. 1, pp. 2156. https://doi.org/10.1038/s41467-024-45978-6

Premature senescence and cardiovascular disease following cancer treatments: mechanistic insights
Jain, A, Casanova, D, Padilla, AV, Paniagua Bojorges, A, Kotla, S, Ko, KA, Samanthapudi, VSK, Chau, K, Nguyen, MTH, Wen, J, Hernandez Gonzalez, SL, Rodgers, SP, Olmsted-Davis, EA, Hamilton, DJ, Reyes-Gibby, C, Yeung, SCJ, Cooke, JP, Herrmann, J, Chini, EN, Xu, X, Yusuf, SW, Yoshimoto, M, Lorenzi, PL, Hobbs, B, Krishnan, S, Koutroumpakis, E, Palaskas, NL, Wang, G, Deswal, A, Lin, SH, Abe, JI & Le, NT 2023, , Frontiers in Cardiovascular Medicine, vol. 10, 1212174, pp. 1212174. https://doi.org/10.3389/fcvm.2023.1212174

Polymer-Functionalized Mitochondrial Transplantation to Fibroblasts Counteracts a Pro-Fibrotic Phenotype
Baudo, G, Wu, S, Massaro, M, Liu, H, Lee, H, Zhang, A, Hamilton, DJ & Blanco, E 2023, , International journal of molecular sciences, vol. 24, no. 13, 10913. https://doi.org/10.3390/ijms241310913

Polymer-Functionalized Mitochondrial Transplantation to Fibroblasts Counteracts a Pro-Fibrotic Phenotype
Baudo, G, Wu, S, Massaro, M, Liu, H, Lee, H, Zhang, A, Hamilton, DJ & Blanco, E 2023, , International journal of molecular sciences, vol. 24, no. 13, 10913. https://doi.org/10.3390/ijms241310913

An ERK5-NRF2 Axis Mediates Senescence-Associated Stemness and Atherosclerosis
Abe, J-I, Imanishi, M, Li, S, Zhang, A, Ko, KA, Samanthapudi, VSK, Lee, L-L, Bojorges, AP, Gi, YJ, Hobbs, BP, Deswal, A, Herrmann, J, Lin, SH, Chini, EN, Shen, YH, Schadler, KL, Nguyen, T-H-M, Gupte, AA, Reyes-Gibby, C, Yeung, S-CJ, Abe, RJ, Olmsted-Davis, EA, Krishnan, S, Dantzer, R, Palaskas, NL, Cooke, JP, Pownall, HJ, Yoshimoto, M, Fujiwara, K, Hamilton, DJ, Burks, JK, Wang, G, Le, N-T & Kotla, S 2023, , Circulation Research, vol. 133, no. 1, pp. 25-44. https://doi.org/10.1161/CIRCRESAHA.122.322017

The efficacy and safety of burosumab in two patients with cutaneous skeletal hypophosphatemia syndrome
Sugarman, J, Maruri, A, Hamilton, DJ, Tabatabai, L, Luca, D, Cimms, T, Krolczyk, S, Roberts, MS & Carpenter, TO 2023, , Bone, vol. 166, 116598, pp. 116598. https://doi.org/10.1016/j.bone.2022.116598

AIBP Regulates Metabolism of Ketone and Lipids but Not Mitochondrial Respiration
Kim, JD, Zhou, T, Zhang, A, Li, S, Gupte, AA, Hamilton, DJ & Fang, L 2022, , Cells, vol. 11, no. 22, 3643. https://doi.org/10.3390/cells11223643, https://doi.org/10.3390/cells11223643

Dynamic Tumor-Specific MHC-II Immuno-PET Predicts the Efficacy of Checkpoint Inhibitor Immunotherapy in Melanoma
Yang, Z, Li, F, Huang, Y, Yin, N, Chu, J, Ma, Y, Pettigrew, RI, Hamilton, DJ, Martin, DR & Li, Z 2022, , Journal of nuclear medicine : official publication, Society of Nuclear Medicine, vol. 63, no. 11, pp. 1708-1714. https://doi.org/10.2967/jnumed.121.263151

AIBP Regulates Metabolism of Ketone and Lipids but Not Mitochondrial Respiration
Kim, JD, Zhou, T, Zhang, A, Li, S, Gupte, AA, Hamilton, DJ & Fang, L 2022, , Cells, vol. 11, no. 22, 3643. https://doi.org/10.3390/cells11223643

Enhanced Succinate Oxidation with Mitochondrial Complex II Reactive Oxygen Species Generation in Human Prostate Cancer
Zhang, A, Gupte, AA, Chatterjee, S, Li, S, Ayala, A, Miles, BJ & Hamilton, DJ 2022, , International journal of molecular sciences, vol. 23, no. 20, 12168, pp. 12168. https://doi.org/10.3390/ijms232012168, https://doi.org/10.3390/ijms232012168

Enhanced Succinate Oxidation with Mitochondrial Complex II Reactive Oxygen Species Generation in Human Prostate Cancer
Zhang, A, Gupte, AA, Chatterjee, S, Li, S, Ayala, AG, Miles, BJ & Hamilton, DJ 2022, , International journal of molecular sciences, vol. 23, no. 20. https://doi.org/10.3390/ijms232012168


Enhanced Succinate Oxidation with Mitochondrial Complex II Reactive Oxygen Species Generation in Human Prostate Cancer
Zhang, A, Gupte, AA, Chatterjee, S, Li, S, Ayala, A, Miles, BJ & Hamilton, DJ 2022, , International journal of molecular sciences, vol. 23, no. 20, 12168. https://doi.org/10.3390/ijms232012168

Suppression of FOXP3 expression by the AP-1 family transcription factor BATF3 requires partnering with IRF4
Arnold, PR, Wen, M, Zhang, L, Ying, Y, Xiao, X, Chu, X, Wang, G, Zhang, X, Mao, Z, Zhang, A, Hamilton, DJ, Chen, W & Li, XC 2022, , Frontiers in immunology, vol. 13, 966364, pp. 966364. https://doi.org/10.3389/fimmu.2022.966364, https://doi.org/10.3389/fimmu.2022.966364

Suppression of FOXP3 expression by the AP-1 family transcription factor BATF3 requires partnering with IRF4
Arnold, PR, Wen, M, Zhang, L, Ying, Y, Xiao, X, Chu, X, Wang, G, Zhang, X, Mao, Z, Zhang, A, Hamilton, DJ, Chen, W & Li, XC 2022, , Frontiers in immunology, vol. 13, 966364. https://doi.org/10.3389/fimmu.2022.966364

The Role of Calcium Signaling in Melanoma
Zhang, H, Chen, Z, Zhang, A, Gupte, AA & Hamilton, DJ 2022, , International journal of molecular sciences, vol. 23, no. 3, 1010. https://doi.org/10.3390/ijms23031010

Polymer-Functionalized Mitochondrial Transplantation to Plaque Macrophages as a Therapeutic Strategy Targeting Atherosclerosis
Liu, H, Wu, S, Lee, H, Baudo, G, Massaro, M, Zhang, A, Hamilton, DJ & Blanco, E 2022, , advanced therapeutics, vol. 5, no. 5, 2100232. https://doi.org/10.1002/adtp.202100232

Nucleus-mitochondria positive feedback loop formed by ERK5 S496 phosphorylation-mediated poly (ADP-ribose) polymerase activation provokes persistent pro-inflammatory senescent phenotype and accelerates coronary atherosclerosis after chemo-radiation
Kotla, S, Zhang, A, Imanishi, M, Ko, KA, Lin, SH, Gi, YJ, Moczygemba, M, Isgandarova, S, Schadler, KL, Chung, C, Milgrom, SA, Banchs, J, Yusuf, SW, Amaya, DN, Guo, H, Thomas, TN, Shen, YH, Deswal, A, Herrmann, J, Kleinerman, ES, Entman, ML, Cooke, JP, Schifitto, G, Maggirwar, SB, McBeath, E, Gupte, AA, Krishnan, S, Patel, ZS, Yoon, Y, Burks, JK, Fujiwara, K, Brookes, PS, Le, N-T, Hamilton, DJ & Abe, J-I 2021, , Redox Biology, vol. 47, 102132, pp. 102132. https://doi.org/10.1016/j.redox.2021.102132