Clinical Trials

    TRITON-PN: A Study to Evaluate the Efficacy and Safety of Nucresiran in Patients With Hereditary Transthyretin Amyloidosis With Polyneuropathy (TRITON-PN)

    Investigator: Sheetal Shroff

    Study Coordinator: Delrose Vernon

    Status: Enrolling

    ClinicalTrials.gov Number: NCT07223203

    Phone: 346.238.9068

    Protocol Number: PRO00043612

    Description


    The purpose of this study is to: Determine the efficacy of nucresiran in patients with hATTR-PN by evaluating the effect on neurologic impairment, quality of life, nutritional status, disability, and gait speed Demonstrate superiority of nucresiran compared to in-study vutrisiran with respect to serum transthyretin (TTR) levels