Weiming Xia

Weiming Xia, PhD

Associate Affiliate Member, Research Institute
Houston Methodist


Laser induced breakdown spectroscopy for the rapid detection of SARS-CoV-2 immune response in plasma
Berlo, K, Xia, W, Zwillich, F, Gibbons, E, Gaudiuso, R, Ewusi-Annan, E, Chiklis, GR & Melikechi, N 2022, , Scientific Reports, vol. 12, no. 1, 1614. https://doi.org/10.1038/s41598-022-05509-z

Longitudinal analysis of antibody decay in convalescent COVID-19 patients
Xia, W, Li, M, Wang, Y, Kazis, LE, Berlo, K, Melikechi, N & Chiklis, GR 2021, , Scientific Reports, vol. 11, no. 1, 16796, pp. 16796. https://doi.org/10.1038/s41598-021-96171-4

Cytokine levels in human vitreous in proliferative diabetic retinopathy
Loporchio, DF, Tam, EK, Cho, J, Chung, J, Jun, GR, Xia, W, Fiorello, MG, Siegel, NH, Ness, S, Stein, TD & Subramanian, ML 2021, , Cells, vol. 10, no. 5, 1069. https://doi.org/10.3390/cells10051069

The association of COVID-19 occurrence and severity with the use of angiotensin converting enzyme inhibitors or angiotensin-II receptor blockers in patients with hypertension
Li, M, Wang, Y, Ndiwane, N, Orner, MB, Palacios, N, Mittler, B, Berlowitz, D, Kazis, LE & Xia, W 2021, , PLoS ONE, vol. 16, no. 3, e0248652, pp. e0248652. https://doi.org/10.1371/journal.pone.0248652

Lifelong chronic psychosocial stress induces a proteomic signature of Alzheimer's disease in wildtype mice
Lyons, CE, Zhou, X, Razzoli, M, Chen, M, Xia, W, Ashe, K, Zhang, B & Bartolomucci, A 2022, , European Journal of Neuroscience, vol. 55, no. 9-10, pp. 2971-2985. https://doi.org/10.1111/ejn.15329

Integrative brain transcriptome analysis links complement component 4 and HSPA2 to the APOE e2 protective effect in Alzheimer disease
Panitch, R, Hu, J, Chung, J, Zhu, C, Meng, G, Xia, W, Bennett, DA, Lunetta, KL, Ikezu, T, Au, R, Stein, TD, Farrer, LA & Jun, GR 2021, , Molecular Psychiatry, vol. 26, no. 10, pp. 6054-6064. https://doi.org/10.1038/s41380-021-01266-z

Tau phosphorylation sites serine202 and serine396 are differently altered in chronic traumatic encephalopathy and Alzheimer's disease
Stathas, SA, Alvarez, VE, Xia, W, Nicks, R, Meng, G, Daley, S, Pothast, M, Shah, A, Kelley, H, Esnault, C, McCormack, R, Dixon, E, Fishbein, L, Cherry, JD, Huber, BR, Tripodis, Y, Alosco, ML, Mez, J, McKee, AC & Stein, TD 2021, , Alzheimers and Dementia. https://doi.org/10.1002/alz.12502

Associations between brain inflammatory profiles and human neuropathology are altered based on apolipoprotein E e4 genotype
Friedberg, JS, Aytan, N, Cherry, JD, Xia, W, Standring, OJ, Alvarez, VE, Nicks, R, Svirsky, S, Meng, G, Jun, G, Ryu, H, Au, R & Stein, TD 2020, , Scientific Reports, vol. 10, no. 1, 2924. https://doi.org/10.1038/s41598-020-59869-5

CCL2 is associated with microglia and macrophage recruitment in chronic traumatic encephalopathy
Cherry, JD, Meng, G, Daley, S, Xia, W, Svirsky, S, Alvarez, VE, Nicks, R, Pothast, M, Kelley, H, Huber, B, Tripodis, Y, Alosco, ML, Mez, J, McKee, AC & Stein, TD 2020, , Journal of Neuroinflammation, vol. 17, no. 1, 370. https://doi.org/10.1186/s12974-020-02036-4

Integrative Brain Transcriptome Analysis Links Complement Component 4 and HSPA2 to the APOE e2 Protective Effect in Alzheimer Disease
Panitch, R, Hu, J, Chung, J, Zhu, C, Meng, G, Xia, W, Bennett, DA, Lunetta, KL, Ikezu, T, Au, R, Stein, TD, Farrer, LA & Jun, GR 2020, , medRxiv : the preprint server for health sciences. https://doi.org/10.1101/2020.11.23.20235762

Protein phosphatase 2A, complement component 4, and APOE genotype linked to Alzheimer’s disease using a systems biology approach
The Alzheimer’s Disease Genetics Consortium 2020, , Unknown Journal. https://doi.org/10.1101/2020.11.20.20235051

Neurofilament light chain in the vitreous humor of the eye
Subramanian, ML, Vig, V, Chung, J, Fiorello, MG, Xia, W, Zetterberg, H, Blennow, K, Zetterberg, M, Shareef, F, Siegel, NH, Ness, S, Jun, GR & Stein, TD 2020, , Alzheimers Research and Therapy, vol. 12, no. 1, 111. https://doi.org/10.1186/s13195-020-00677-4

Diagnosis of Alzheimer's disease using laser-induced breakdown spectroscopy and machine learning
Gaudiuso, R, Ewusi-Annan, E, Xia, W & Melikechi, N 2020, , Spectrochimica Acta - Part B Atomic Spectroscopy, vol. 171, 105931. https://doi.org/10.1016/j.sab.2020.105931

Targeting Amyloidogenic Processing of APP in Alzheimer’s Disease
Zhao, J, Liu, X, Xia, W, Zhang, Y & Wang, C 2020, , Frontiers in Molecular Neuroscience, vol. 13, 137. https://doi.org/10.3389/fnmol.2020.00137

Proteomic Profiling of Plasma and Brain Tissue from Alzheimer's Disease Patients Reveals Candidate Network of Plasma Biomarkers
Chen, M & Xia, W 2020, , Journal of Alzheimers Disease, vol. 76, no. 1, pp. 349-368. https://doi.org/10.3233/JAD-200110

Proteomic and biological profiling of extracellular vesicles from Alzheimer's disease human brain tissues
Muraoka, S, DeLeo, AM, Sethi, MK, Yukawa-Takamatsu, K, Yang, Z, Ko, J, Hogan, JD, Ruan, Z, You, Y, Wang, Y, Medalla, M, Ikezu, S, Chen, M, Xia, W, Gorantla, S, Gendelman, HE, Issadore, D, Zaia, J & Ikezu, T 2020, , Alzheimers and Dementia, vol. 16, no. 6, pp. 896-907. https://doi.org/10.1002/alz.12089

Assessment of separation methods for extracellular vesicles from human and mouse brain tissues and human cerebrospinal fluids
Muraoka, S, Lin, W, Chen, M, Hersh, SW, Emili, A, Xia, W & Ikezu, T 2020, , Methods, vol. 177, pp. 35-49. https://doi.org/10.1016/j.ymeth.2020.02.002

Beneficial association of angiotensin-converting enzyme inhibitors and statins on the occurrence of possible Alzheimer's disease after traumatic brain injury
Li, M, Reisman, J, Morris-Eppolito, B, Qian, SX, Kazis, LE, Wolozin, B, Goldstein, LE & Xia, W 2020, , Alzheimers Research and Therapy, vol. 12, no. 1, 33. https://doi.org/10.1186/s13195-020-00589-3

Amyloid-ß42/40 ratio drives tau pathology in 3D human neural cell culture models of Alzheimer’s disease
Kwak, SS, Washicosky, KJ, Brand, E, von Maydell, D, Aronson, J, Kim, S, Capen, DE, Cetinbas, M, Sadreyev, R, Ning, S, Bylykbashi, E, Xia, W, Wagner, SL, Choi, SH, Tanzi, RE & Kim, DY 2020, , Nature Communications, vol. 11, no. 1, 1377. https://doi.org/10.1038/s41467-020-15120-3

Developmental pathogenicity of 4-repeat human tau is lost with the P301L mutation in genetically matched tau-transgenic mice
Gamache, JE, Kemper, L, Steuer, E, Leinonen-Wright, K, Choquette, JM, Hlynialuk, C, Benzow, K, Vossel, KA, Xia, W, Koob, MD & Ashe, KH 2020, , Journal of Neuroscience, vol. 40, no. 1, pp. 220-236. https://doi.org/10.1523/JNEUROSCI.1256-19.2019