Assistant Research Professor of Cell and Molecular Biology in Oncology, Institute for Academic Medicine
Assistant Research Member & Director, Advanced Cellular & Tissue Imaging Core, Research Institute
Dr. Cui earned his Ph.D. in Integrative Medicine and Neurobiology from the Shanghai Medical College of Fudan University, Shanghai, China, in 2005. He held faculty appointments at the Department of Integrative Medicine in Shanghai Medical College of Fudan University, Shanghai, China, before becoming a member of the Houston Methodist Research Institute in 2007.
Dr. Cui’s research uses integrated systems biology approaches to discover new strategies for treating malignant tumors, especially primary (glioblastoma) and secondary (metastatic) brain tumors. He is applying multidisciplinary approaches, including assay development, high-throughput and high-content screening, as well as computational modeling to discover new compounds and explore new treatment combinations. He developed a screening platform for glioma growth and invasion using bioluminescence imaging and uses it to screen potential drugs that inhibit tumor cell migration for better management of malignant glioblastoma. He has investigated a new cocktail strategy for treating brain tumors by combining whole brain radiotherapy, a neuroprotection compound, and an angiogenesis inhibitor. He has also obtained pilot project funding from the NCI to conduct his studies. His new drug combination study on brain tumors is under study in a new clinical trial in collaboration with Dr. Pamela New at the HMH and Dr. Diana Chow at the University of Houston.