Jose Thaiparambil, PhD

Instructor in Medicine, Academic Institute
Instructor, Research Institute
Houston Methodist


Cigarette smoke condensate induces centrosome clustering in normal lung epithelial cells
Thaiparambil, J, Amara, CS, Sen, S, Putluri, N & El-Zein, R 2023, , Cancer Medicine, vol. 12, no. 7, pp. 8499-8509. https://doi.org/10.1002/cam4.5599

Editorial: Sirtuins From Bench to Bedside: How Far Are We?
Thaiparambil, J 2022, , Frontiers in Physiology, vol. 13, 907501. https://doi.org/10.3389/fphys.2022.907501

Integrative metabolomics and transcriptomics analysis reveals novel therapeutic vulnerabilities in lung cancer
Thaiparambil, J, Dong, J, Grimm, SL, Perera, D, Ambati, CSR, Putluri, V, Robertson, MJ, Patel, TD, Mistretta, B, Gunaratne, PH, Kim, MP, Yustein, JT, Putluri, N, Coarfa, C & El-Zein, R 2023, , Cancer Medicine, vol. 12, no. 1, pp. 584-596. https://doi.org/10.1002/cam4.4933

Mitotic spindle apparatus abnormalities in chronic obstructive pulmonary disease cells: A potential pathway to lung cancer
Thaiparambil, J, Dong, L, Jasso, D, Huang, JA & El-Zein, RA 2020, , Cancer Prevention Research, vol. 13, no. 11, pp. 923-933. https://doi.org/10.1158/1940-6207.CAPR-19-0557

2-Methoxyestradiol sensitizes breast cancer cells to taxanes by targeting centrosomes
El-Zein, R, Thaiparambil, J & Abdel-Rahman, SZ 2020, , Oncotarget, vol. 0, no. 0. https://doi.org/10.18632/oncotarget.27810

2-methoxyestradiol sensitizes breast cancer cells to taxanes by targeting centrosomes
El-Zein, R, Thaiparambil, J & Abdel-Rahman, SZ 2020, , Oncotarget, vol. 11, no. 48, pp. 4479-4489. https://doi.org/10.18632/ONCOTARGET.27810

Oxidative DNA adducts detected in vitro from redox activity of cigarette smoke constituents
Vadhanam, MV, Thaiparambil, J, Gairola, CG & Gupta, RC 2012, , Chemical Research in Toxicology, vol. 25, no. 11, pp. 2499-2504. https://doi.org/10.1021/tx300312f

AMPK regulates mitotic spindle orientation through phosphorylation of myosin regulatory light chain
Thaiparambil, JT, Eggers, CM & Marcus, AI 2012, , Molecular and Cellular Biology, vol. 32, no. 16, pp. 3203-3217. https://doi.org/10.1128/MCB.00418-12

Withaferin A inhibits breast cancer invasion and metastasis at sub-cytotoxic doses by inducing vimentin disassembly and serine 56 phosphorylation
Thaiparambil, JT, Bender, L, Ganesh, T, Kline, E, Patel, P, Liu, Y, Tighiouart, M, Vertino, PM, Harvey, RD, Garcia, A & Marcus, AI 2011, , International Journal of Cancer, vol. 129, no. 11, pp. 2744-2755. https://doi.org/10.1002/ijc.25938

Colon tumor cell growth-inhibitory activity of sulindac sulfide and other nonsteroidal anti-inflammatory drugs is associated with phosphodiesterase 5 inhibition
Tinsley, HN, Gary, BD, Thaiparambil, J, Li, N, Lu, W, Li, Y, Maxuitenko, YY, Keeton, AB & Piazza, GA 2010, , Cancer Prevention Research, vol. 3, no. 10, pp. 1303-1313. https://doi.org/10.1158/1940-6207.CAPR-10-0030

A novel sulindac derivative that does not inhibit cyclooxygenases but potently inhibits colon tumor cell growth and induces apoptosis with antitumor activity
Piazza, GA, Keeton, AB, Tinsley, HN, Gary, BD, Whitt, JD, Mathew, B, Thaiparambil, J, Coward, L, Gorman, G, Li, Y, Sani, B, Hobrath, JV, Maxuitenko, YY & Reynolds, RC 2009, , Cancer Prevention Research, vol. 2, no. 6, pp. 572-580. https://doi.org/10.1158/1940-6207.CAPR-09-0001

Synthesis of novel tadalafil analogues and their evaluation as phosphodiesterase inhibitors and anticancer agents
Abadi, AH, Abouel-Ella, DA, Ahmed, NS, Gary, BD, Thaiparambil, JT, Tinsley, HN, Keeton, AB & Piazza, GA 2009, , Arzneimittel-Forschung/Drug Research, vol. 59, no. 8, pp. 415-421. https://doi.org/10.1055/s-0031-1296417

Time-dependent formation of 8-oxo-deoxyguanosine in the lungs of mice exposed to cigarette smoke
Thaiparambil, JT, Vadhanam, MV, Srinivasan, C, Gairola, CG & Gupta, RC 2007, , Chemical Research in Toxicology, vol. 20, no. 12, pp. 1737-1740. https://doi.org/10.1021/tx700289g