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Guangjun Nie, PhD

Full Affiliate Member, Research Institute
Houston Methodist


Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem
Han, X, Li, Y, Xu, Y, Zhao, X, Zhang, Y, Yang, X, Wang, Y, Zhao, R, Anderson, GJ, Zhao, Y & Nie, G 2018, Nature Communications, vol. 9, no. 1, 3390. DOI: 10.1038/s41467-018-05906-x

A CRISPR-Cas13a system for efficient and specific therapeutic targeting of mutant KRAS for pancreatic cancer treatment
Zhao, X, Liu, L, Lang, J, Cheng, K, Wang, Y, Li, X, Shi, J, Wang, Y & Nie, G 2018, Cancer Letters, vol. 431, pp. 171-181. DOI: 10.1016/j.canlet.2018.05.042

Delivery of small interfering RNA against Nogo-B receptor via tumor-acidity responsive nanoparticles for tumor vessel normalization and metastasis suppression
Wang, B, Ding, Y, Zhao, X, Han, X, Yang, N, Zhang, Y, Zhao, Y, Zhao, X, Taleb, M, Miao, QR & Nie, G 2018, Biomaterials, vol. 175, pp. 110-122. DOI: 10.1016/j.biomaterials.2018.05.034

Surface Functionalization of Polymeric Nanoparticles with Umbilical Cord-Derived Mesenchymal Stem Cell Membrane for Tumor-Targeted Therapy
Yang, N, Ding, Y, Zhang, Y, Wang, B, Zhao, X, Cheng, K, Huang, Y, Taleb, M, Zhao, J, Dong, WF, Zhang, L & Nie, G 2018, ACS Applied Materials and Interfaces, vol. 10, no. 27, pp. 22963-22973. DOI: 10.1021/acsami.8b05363

Sustained release of sodium deoxycholate from PLGA–PEG–PLGA thermosensitive polymer
Nasrollahi, P, Khajeh, K, Tamjid, E, Taleb, M, Soleimani, M & Nie, G 2018, Artificial Cells, Nanomedicine and Biotechnology, pp. 1-8. DOI: 10.1080/21691401.2018.1481861

Nanomedicine Assembled by Coordinated Selenium-Platinum Complexes Can Selectively Induce Cytotoxicity in Cancer Cells by Targeting the Glutathione Antioxidant Defense System
Li, F, Li, T, Han, X, Zhuang, H, Nie, G & Xu, H 2018, ACS Biomaterials Science and Engineering, vol. 4, no. 6, pp. 1954-1962. DOI: 10.1021/acsbiomaterials.7b00362

Targeted Brain Delivery of Rabies Virus Glycoprotein 29-Modified Deferoxamine-Loaded Nanoparticles Reverses Functional Deficits in Parkinsonian Mice
You, L, Wang, J, Liu, T, Zhang, Y, Han, X, Wang, T, Guo, S, Dong, T, Xu, J, Anderson, GJ, Liu, Q, Chang, YZ, Lou, X & Nie, G 2018, ACS Nano, vol. 12, no. 5, pp. 4123-4139. DOI: 10.1021/acsnano.7b08172

Sequentially Responsive Therapeutic Peptide Assembling Nanoparticles for Dual-Targeted Cancer Immunotherapy
Cheng, K, Ding, Y, Zhao, Y, Ye, S, Zhao, X, Zhang, Y, Ji, T, Wu, H, Wang, B, Anderson, GJ, Ren, L & Nie, G 2018, Unknown Journal, vol. 18, no. 5, pp. 3250-3258. DOI: 10.1021/acs.nanolett.8b01071

Nanomaterial libraries and model organisms for rapid high-content analysis of nanosafety
Li, Y, Wang, J, Zhao, F, Bai, B, Nie, G, Nel, AE & Zhao, Y 2018, National Science Review, vol. 5, no. 3, pp. 365-388. DOI: 10.1093/nsr/nwx120

Platelet membrane-based and tumor-associated platelet-targeted drug delivery systems for cancer therapy
Zhang, Y, Liu, G, Wei, J & Nie, G 2018, Frontiers of Medicine, pp. 1-11. DOI: 10.1007/s11684-017-0583-y

Doxorubicin and paclitaxel carried by methoxy poly(ethylene glycol)-poly(lactide-co-glycolide) is superior than traditional drug-delivery methods
Hu, Y, Zhu, X, Zhao, R, Wang, J, Song, Y, Nie, G, Tang, H & Wang, Y 2018, Nanomedicine, vol. 13, no. 8, pp. 913-928. DOI: 10.2217/nnm-2017-0363

Imparting Designer Biorecognition Functionality to Metal–Organic Frameworks by a DNA-Mediated Surface Engineering Strategy
Ning, W, Di, Z, Yu, Y, Zeng, P, Di, C, Chen, D, Kong, X, Nie, G, Zhao, Y & Li, L 2018, Small, vol. 14, no. 11, 1703812. DOI: 10.1002/smll.201703812

Precision design of nanomedicines to restore gemcitabine chemosensitivity for personalized pancreatic ductal adenocarcinoma treatment
Zhao, X, Wang, X, Sun, W, Cheng, K, Qin, H, Han, X, Lin, Y, Wang, Y, Lang, J, Zhao, R, Zheng, X, Zhao, Y, shi, J, Hao, J, Miao, QR, Nie, G & Ren, H 2018, Biomaterials, vol. 158, pp. 44-55. DOI: 10.1016/j.biomaterials.2017.12.015

A DNA nanorobot functions as a cancer therapeutic in response to a molecular trigger in vivo
Li, S, Jiang, Q, Liu, S, Zhang, Y, Tian, Y, Song, C, Wang, J, Zou, Y, Anderson, GJ, Han, JY, Chang, Y, Liu, Y, Zhang, C, Chen, L, Zhou, G, Nie, G, Yan, H, Ding, B & Zhao, Y 2018, Nature Biotechnology, vol. 36, no. 3, pp. 258-264. DOI: 10.1038/nbt.4071

Injectable Hexapeptide Hydrogel for Localized Chemotherapy Prevents Breast Cancer Recurrence
Qi, Y, Min, H, Mujeeb, A, Zhang, Y, Han, X, Zhao, X, Anderson, GJ, Zhao, Y & Nie, G 2018, ACS Applied Materials and Interfaces, vol. 10, no. 8, pp. 6972-6981. DOI: 10.1021/acsami.7b19258

Highly Fluorescent Chiral N-S-Doped Carbon Dots from Cysteine: Affecting Cellular Energy Metabolism
Li, F, Li, Y, Yang, X, Han, X, Jiao, Y, Wei, T, Yang, D, Xu, H & Nie, G 2018, Angewandte Chemie - International Edition, vol. 57, no. 9, pp. 2377-2382. DOI: 10.1002/anie.201712453

Robust Anticancer Efficacy of a Biologically Synthesized Tumor Acidity-Responsive and Autophagy-Inducing Functional Beclin 1
Ding, GB, Sun, J, Wu, G, Li, B, Yang, P, Li, Z & Nie, G 2018, ACS Applied Materials and Interfaces, vol. 10, no. 6, pp. 5227-5239. DOI: 10.1021/acsami.7b17454

Chaperonin-GroEL as a Smart Hydrophobic Drug Delivery and Tumor Targeting Molecular Machine for Tumor Therapy
Yuan, Y, Du, C, Sun, C, Zhu, J, Wu, S, Zhang, Y, Ji, T, Lei, J, Yang, Y, Gao, N & Nie, G 2018, Nano Letters, vol. 18, no. 2, pp. 921-928. DOI: 10.1021/acs.nanolett.7b04307

Suppression of Tumor Energy Supply by Liposomal Nanoparticle-Mediated Inhibition of Aerobic Glycolysis
Zhang, Y, Wei, J, Xu, J, Leong, WS, Liu, G, Ji, T, Cheng, Z, Wang, J, Lang, J, Zhao, Y, You, L, Zhao, X, Wei, T, Anderson, GJ, Qi, S, Kong, J, Nie, G & Li, S 2018, ACS Applied Materials and Interfaces, vol. 10, no. 3, pp. 2347-2353. DOI: 10.1021/acsami.7b16685

Identification of CDAN1, C15ORF41 and SEC23B mutations in Chinese patients affected by congenital dyserythropoietic anemia
Wang, Y, Ru, Y, Liu, G, Dong, S, Li, Y, Zhu, X, Zhang, F, Chang, YZ & Nie, G 2018, Gene, vol. 640, pp. 73-78. DOI: 10.1016/j.gene.2017.10.027