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Guangjun Nie, PhD

Full Affiliate Member, Research Institute
Houston Methodist


Publications

Reversing tumor stemness via orally targeted nanoparticles achieves efficient colon cancer treatment
Xu, J, Zhang, Y, Xu, J, Wang, M, Liu, G, Wang, J, Zhao, X, Qi, Y, Shi, J, Cheng, K, Li, Y, Qi, S & Nie, G 2019, Biomaterials, vol. 216, 119247. https://doi.org/10.1016/j.biomaterials.2019.119247

Cooperatively Responsive Peptide Nanotherapeutic that Regulates Angiopoietin Receptor Tie2 Activity in Tumor Microenvironment to Prevent Breast Tumor Relapse after Chemotherapy
Zhang, L, Qi, Y, Min, H, Ni, C, Wang, F, Wang, B, Qin, H, Zhang, Y, Liu, G, Qin, Y, Duan, X, Li, F, Han, X, Tao, N, Zhang, L, Qin, Z, Zhao, Y & Nie, G 2019, ACS Nano, vol. 13, no. 5, pp. 5091-5102. https://doi.org/10.1021/acsnano.8b08142

Announcing the 2019 ACS Nano Award Lecture Laureates
Bunje, H, Millstone, JE, Nie, G, Wee, ATS, Weil, T, Shmakov, SN & Weiss, PS 2019, ACS Nano, vol. 13, no. 5, pp. 4859-4861. https://doi.org/10.1021/acsnano.9b03722

Peptide self-assembly nanoparticles loaded with panobinostat to activate latent human immunodeficiency virus
Kuai, Q, Wang, Y, Gao, F, Qi, Y, Wang, R, Wang, Y, Lu, X, Zhao, Y, Nie, G, He, M, Zhou, H, Jiang, X, Ren, S & Yu, Q 2019, Journal of Biomedical Nanotechnology, vol. 15, no. 5, pp. 979-992. https://doi.org/10.1166/jbn.2019.2764

Co-delivery of gemcitabine and Mcl-1 SiRNA via cationic liposome-based system enhances the efficacy of chemotherapy in pancreatic cancer
Wang, Y, Gao, F, Jiang, X, Zhao, X, Wang, Y, Kuai, Q, Nie, G, He, M, Pan, Y, Shi, W, Ren, S & Yu, Q 2019, Journal of Biomedical Nanotechnology, vol. 15, no. 5, pp. 966-978. https://doi.org/10.1166/jbn.2019.2762

An Extendable Star-Like Nanoplatform for Functional and Anatomical Imaging-Guided Photothermal Oncotherapy
Han, X, Xu, Y, Li, Y, Zhao, X, Zhang, Y, Min, H, Qi, Y, Anderson, GJ, You, L, Zhao, Y & Nie, G 2019, ACS Nano, vol. 13, no. 4, pp. 4379-4391. https://doi.org/10.1021/acsnano.8b09607

Mitochondrial Ferritin Is a Hypoxia-Inducible Factor 1a-Inducible Gene That Protects from Hypoxia-Induced Cell Death in Brain
Wu, Q, Wu, WS, Su, L, Zheng, X, Wu, WY, Santambrogio, P, Gou, YJ, Hao, Q, Wang, PN, Li, YR, Zhao, BL, Nie, G, Levi, S & Chang, YZ 2019, Antioxidants and Redox Signaling, vol. 30, no. 2, pp. 198-212. https://doi.org/10.1089/ars.2017.7063

Targeted Co-delivery of the Iron Chelator Deferoxamine and a HIF1a Inhibitor Impairs Pancreatic Tumor Growth
Lang, J, Zhao, X, Wang, X, Zhao, Y, Li, Y, Zhao, R, Cheng, K, Li, Y, Han, X, Zheng, X, Qin, H, Geranpayehvaghei, M, Shi, J, Anderson, GJ, Hao, J, Ren, H & Nie, G 2019, ACS Nano. https://doi.org/10.1021/acsnano.8b08823

Biomimetic Metal–Organic Framework Nanoparticles for Cooperatively Combination of Antiangiogenesis and Photodynamic Therapy for Enhanced Efficacy
Min, H, Wang, J, Qi, Y, Zhang, Y, Han, X, Xu, Y, Xu, J, Li, Y, Chen, L, Cheng, K, Liu, G, Yang, N, Li, Y & Nie, G 2019, Advanced Materials. https://doi.org/10.1002/adma.201808200

Anticancer Activities of Tumor-killing Nanorobots
Li, S, Jiang, Q, Ding, B & Nie, G 2019, Trends in Biotechnology. https://doi.org/10.1016/j.tibtech.2019.01.010

Tumor-Specific Silencing of Tissue Factor Suppresses Metastasis and Prevents Cancer-Associated Hypercoagulability
Liu, S, Zhang, Y, Zhao, X, Wang, J, Di, C, Zhao, Y, Ji, T, Cheng, K, Wang, Y, Chen, L, Qi, Y, Li, S & Nie, G 2019, Nano Letters. https://doi.org/10.1021/acs.nanolett.9b01785

Engineering Biomimetic Platesomes for pH-Responsive Drug Delivery and Enhanced Antitumor Activity
Liu, G, Zhao, X, Zhang, Y, Xu, J, Xu, J, Li, Y, Min, H, Shi, J, Zhao, Y, Wei, J, Wang, J & Nie, G 2019, Advanced Materials. https://doi.org/10.1002/adma.201900795

Reversal of pancreatic desmoplasia by re-educating stellate cells with a tumour microenvironment-activated nanosystem
Han, X, Li, Y, Xu, Y, Zhao, X, Zhang, Y, Yang, X, Wang, Y, Zhao, R, Anderson, GJ, Zhao, Y & Nie, G 2018, Nature communications, vol. 9, no. 1, 3390. https://doi.org/10.1038/s41467-018-05906-x

Precise nanomedicine for intelligent therapy of cancer
Chen, H, Gu, Z, An, H, Chen, C, Chen, J, Cui, R, Chen, S, Chen, W, Chen, X, Chen, X, Chen, Z, Ding, B, Dong, Q, Fan, Q, Fu, T, Hou, D, Jiang, Q, Ke, H, Jiang, X, Liu, G, Li, S, Li, T, Liu, Z, Nie, G, Ovais, M, Pang, D, Qiu, N, Shen, Y, Tian, H, Wang, C, Wang, H, Wang, Z, Xu, H, Xu, JF, Yang, X, Zhu, S, Zheng, X, Zhang, X, Zhao, Y, Tan, W, Zhang, X & Zhao, Y 2018, Science China Chemistry, vol. 61, no. 12, pp. 1503-1552. https://doi.org/10.1007/s11426-018-9397-5

Epidermal Growth Factor Receptor-Targeting Peptide Nanoparticles Simultaneously Deliver Gemcitabine and Olaparib to Treat Pancreatic Cancer with Breast Cancer 2 (BRCA2) Mutation
Du, C, Qi, Y, Zhang, Y, Wang, Y, Zhao, X, Min, H, Han, X, Lang, J, Qin, H, Shi, Q, Zhang, Z, Tian, X, Anderson, GJ, Zhao, Y, Nie, G & Yang, Y 2018, ACS Nano, vol. 12, no. 11, pp. 10785-10796. https://doi.org/10.1021/acsnano.8b01573

Specific tissue factor delivery using a tumor-homing peptide for inducing tumor infarction
Shi, Q, Zhang, Y, Liu, S, Liu, G, Xu, J, Zhao, X, Anderson, GJ, Nie, G & Li, S 2018, Biochemical pharmacology, vol. 156, pp. 501-510. https://doi.org/10.1016/j.bcp.2018.09.020

Polymeric Nanoparticles Enhance the Ability of Deferoxamine to Deplete Hepatic and Systemic Iron
Guo, S, Liu, G, Frazer, DM, Liu, T, You, L, Xu, J, Wang, Y, Anderson, GJ & Nie, G 2018, Nano Letters, vol. 18, no. 9, pp. 5782-5790. https://doi.org/10.1021/acs.nanolett.8b02428

A CRISPR-Cas13a system for efficient and specific therapeutic targeting of mutant KRAS for pancreatic cancer treatment
Zhao, X, Liu, L, Lang, J, Cheng, K, Wang, Y, Li, X, Shi, J, Wang, Y & Nie, G 2018, Cancer Letters, vol. 431, pp. 171-181. https://doi.org/10.1016/j.canlet.2018.05.042

Delivery of small interfering RNA against Nogo-B receptor via tumor-acidity responsive nanoparticles for tumor vessel normalization and metastasis suppression
Wang, B, Ding, Y, Zhao, X, Han, X, Yang, N, Zhang, Y, Zhao, Y, Zhao, X, Taleb, M, Miao, QR & Nie, G 2018, Biomaterials, vol. 175, pp. 110-122. https://doi.org/10.1016/j.biomaterials.2018.05.034

Surface Functionalization of Polymeric Nanoparticles with Umbilical Cord-Derived Mesenchymal Stem Cell Membrane for Tumor-Targeted Therapy
Yang, N, Ding, Y, Zhang, Y, Wang, B, Zhao, X, Cheng, K, Huang, Y, Taleb, M, Zhao, J, Dong, WF, Zhang, L & Nie, G 2018, ACS Applied Materials and Interfaces, vol. 10, no. 27, pp. 22963-22973. https://doi.org/10.1021/acsami.8b05363

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