Brian A. Bruckner, MD, PhD, MBA

Assistant Professor of Clinical Cardiovascular Surgery, Institute for Academic Medicine
Assistant Research Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Bruckner is a cardiovascular surgeon at the Methodist DeBakey Heart and Vascular Center at the Methodist Hospital in Houston, Texas. His specialties include cardiothoracic, transplant surgery and placement of left ventricular assist devices (LVADs). In January 2007, he was inducted in to the “Cooley Hands” International Surgical Society. Dr. Bruckner is a member of the American Medical Association, the Harris County Medical Society, the Society of Artificial Organs and the International Society of Heart & Lung Transplantation.

Description of Research

Dr. Bruckner´s research centers around cardiac stem cell therapies for heart failure patients, and myocardial modeling during LVAD support.

Areas Of Expertise

Stem cells Myocardial modeling LVADs
Education & Training

Residency, Baylor College of Medicine
Clinical Fellowship, Baylor College of Medicine
MD, University of Florida
Active Clinical Trials

HeartMate III Study

NCT02279979


ACT Registry

NCT02145858


Heartware DT Supplement Study

NCT01966458

Publications

Retransplantation Outcomes at a Large Lung Transplantation Program
Ren, D, Kaleekal, TS, Graviss, EA, Nguyen, DT, Sinha, N, Goodarzi, A, Agboli, I, Suarez, EE, Loebe, M, Scheinin, SA & Bruckner, BA 2018, Transplantation Direct, vol. Online Now. DOI: 10.1097/TXD.0000000000000844

A Multisite Randomized Controlled Trial of a Patient-Centered Ventricular Assist Device Decision Aid (VADDA Trial)
Kostick, KM, Bruce, CR, Minard, CG, Volk, RJ, Civitello, A, Krim, SR, Horstmanshof, D, Thohan, V, Loebe, M, Hanna, M, Bruckner, BA, Blumenthal­Barby, JS & Estep, JD 2018, Journal of Cardiac Failure, vol. 24, no. 10, pp. 661-671. DOI: 10.1016/j.cardfail.2018.08.008

Controlled Intrapericardial Delivery of Prostaglandin Formulations For Heart Failure
Filgueira, CS, Igo, SR, Bruckner, BA, Ferraro, F, Di Marzio, N, Vighetto, V & Grattoni, A 2018, Annual Meeting & Exposition of the Controlled Release Society, 7/22/18 - 7/24/18, .

Switching-offAdora2b in vascular smooth muscle cells halts the development of pulmonary hypertension
Mertens, TCJ, Hanmandlu, A, Tu, L, Phan, C, Collum, SD, Chen, NY, Weng, T, Davies, J, Liu, C, Eltzschig, HK, Jyothula, SSK, Rajagopal, K, Xia, Y, Guha, A, Bruckner, BA, Blackburn, MR, Guignabert, C & Karmouty-Quintana, H 2018, Frontiers in Physiology, vol. 9, no. JUN, 555. DOI: 10.3389/fphys.2018.00555

PLGA Particles-Based System For Intrapericardial Delivery of Prostaglandin Through HeartPAS™
Di Marzio, N, Vighetto, V, Hirsch, M, Filgueira, CS, Igo, SR, Bruckner, BA, Ferraro, F, Shah, DJ, Estep, JD & Grattoni, A 2018, .

PLGA Particles-Based System For Intrapericardial Delivery of Prostaglandin Through HeartPAS
Di Marzio, N, Vighetto, V, Filgueira, CS, Igo, SR, Bruckner, BA, Ferraro, F, Shah, DJ, Estep, JD & Grattoni, A 2018, Kavli Foundation Workshop “Sensing the Future: The Future of Sensing”, Houston, United States, 5/7/18, .

PLGA Particles-Based System For Intrapericardial Delivery of Prostaglandin Through HeartPAS™
Di Marzio, N, Vighetto, V, Filgueira, CS, Igo, SR, Bruckner, BA, Ferraro, F, Shah, DJ, Estep, JD & Grattoni, A 2018, Lasker lecture & Biomedical Imaging Symposium, Houston, United States, 4/26/18, .

Two-year outcomes with a magnetically levitated cardiac pump in heart failure
Mehra, MR, Goldstein, DJ, Uriel, N, Cleveland, JC, Yuzefpolskaya, M, Salerno, C, Walsh, MN, Milano, CA, Patel, CB, Ewald, GA, Itoh, A, Dean, D, Krishnamoorthy, A, Cotts, WG, Tatooles, AJ, Jorde, UP, Bruckner, BA, Estep, JD, Jeevanandam, V, Sayer, G, Horstmanshof, D, Long, JW, Gulati, S, Skipper, ER, OConnell, JB, Heatley, G, Sood, P & Naka, Y 2018, New England Journal of Medicine, vol. 378, no. 15, pp. 1386-1395. DOI: 10.1056/NEJMoa1800866

IABP as a Bridge to Transplantation: Can we Identify Who May Benefit From a LVAD?
Guha, A, Ali, A, Nguyen, DT, Bruckner, B, Trachtenberg, B, Graviss, EA, Bhimaraj, A, Park, MH, Hussain, I, Suarez, EE, Torre-Amione, G & Estep, J 2018, Journal of Heart and Lung Transplantation, vol. 37, no. 4, pp. S267. DOI: 10.1016/j.healun.2018.01.667

Long-Term Survival in Bilateral Lung Transplantation for Scleroderma-Related Lung Disease
Chan, EY, Goodarzi, A, Sinha, N, Nguyen, DT, Youssef, JG, Suarez, EE, Kaleekal, T, Graviss, EA, Bruckner, BA, MacGillivray, TE & Scheinin, SA 2018, Annals of Thoracic Surgery, vol. 105, no. 3, pp. 893-900. DOI: 10.1016/j.athoracsur.2017.09.038

PLGA Particle-Based System For Intrapericardial Delivery of Prostaglandin Through HeartPAS™
Di Marzio, N, Vighetto, V, Filgueira, CS, Igo, SR, Bruckner, BA, Ferraro, F, Shah, DJ, Estep, JD & Grattoni, A 2018, 2018 Department of Nanomedicine Symposium, Houston, United States, 2/28/18, .

PLGA Particles Based Delivery System for Intrapericardial Delivery of Prostaglandin through HeartPAS™
Di Marzio, N, Vighetto, V, Filgueira, CS, Igo, S, Bruckner, BA, Ferraro, F, Shah, DJ, Estep, JD & Grattoni, A 2018, MAPTA Winter Science Symposium, Houston, United States, 12/1/16, .

Melding a high-risk patient for continuous flow left ventricular assist device into a low-risk patient
Amione-Guerra, J, Cruz-Solbes, AS, Bonilla, HG, Estep, JD, Guha, A, Bhimaraj, A, Suarez, EE, Bruckner, BA, Torre-Amione, G, Park, MH & Trachtenberg, BH 2017, ASAIO Journal, vol. 63, no. 6, pp. 704-712. DOI: 10.1097/MAT.0000000000000591

Controlled Intrapericardial Delivery Of Prostaglandin Formulations For Heart Failure
Filgueira, CS, Igo, SR, Bruckner, BA, Ferraro, F, Shah, DJ, Estep, JD & Grattoni, A 2017, George and Angelina Kostas Research Center for Cardiovascular Medicine , Houston, United States, 10/24/17 - 10/25/17, .

Long-term Survival in Bilateral Lung Transplantation for Scleroderma-Related Lung Disease
Chan, EY, Goodarzi, A, Sinha, N, Nguyen, DTM, Youssef, JG, Suarez, EE, Kaleekal, TS, Graviss, EA, Bruckner, BA, MacGillivray, TE & Scheinin, SA 2017, The Annals of Thoracic Surgery.

Histidine-Tryptophan-Ketoglutarate (HTK) versus celsior in the association with heart transplant outcomes
Dewei, R, Estep, JD, Graviss, EA, Nguyen, DTM, Suarez, E, Macgillivray, T & Bruckner, BA 2017, 27th International Congress of The Transplantation Society, Madrid, Spain, 6/30/18 - 7/5/18, .

The Lung Transplant Risk Model - A Nationally Validated Tool for Pre-Transplant Risk Assessment
Chan, EY, Nguyen, DT, Sinha, N, Kaleekal, TS, Goodarzi, A, Youssef, JG, Bruckner, BA, Suarez, EE, Scheinin, SA, Graviss, EA & Gaber, AO 2017, pp. S114-S115. DOI: 10.1016/j.healun.2017.01.293

Extra Corporeal Membrane Oxygenation (ECMO) as a Bridge to Adult Heart Transplantation: Bridge to Bridge Strategy vs Direct ECMO Bridge Strategy (UNOS Analysis)
Hannawi, B, Estep, J, Nguyen, D, Graviss, E, Trachtenberg, B, Bhimaraj, A, Park, JM, Bruckner, BA & Guha, A 2017, pp. S137. DOI: 10.1016/j.healun.2017.01.359

Caregivers of Patients With Left Ventricular Assist Devices: Possible Impacts on Patients' Mortality and Interagency Registry for Mechanically Assisted Circulatory Support-Defined Morbidity Events
Bruce, CR, Minard, CG, Wilhelms, LA, Abraham, M, Amione-Guerra, J, Pham, L, Grogan, SD, Trachtenberg, B, Smith, ML, Bruckner, BA, Estep, JD & Kostick, KM 2017, Circulation: Cardiovascular Quality and Outcomes, vol. 10, no. 1. DOI: 10.1161/CIRCOUTCOMES.116.002879

Improved Outcomes With the Evolution of a Neoadjuvant Chemotherapy Approach to Right Heart Sarcoma
Abu Saleh, WK, Ramlawi, B, Shapira, OM, Al Jabbari, O, Ravi, V, Benjamin, R, Durand, JB, Leja, MJ, Blackmon, SH, Bruckner, BA & Reardon, MJ 2017, Annals of Thoracic Surgery. DOI: 10.1016/j.athoracsur.2016.10.054