Bradley K. Weiner, MD

Professor of Clinical Orthopedic Surgery, Academic Institute
Full Clinical Member, Research Institute
Program Director, Orthopedic Surgery Residency, Department of Orthopedic Surgery
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Weiner is Professor, Vice Chairman, and Chief of Spinal Surgery within the Department of Orthopaedics at Houston Methodist Medical Center. He serves many institutional roles including Chair of Business Practices for the Research Institute and Medical Director of The Surgical Advanced Technology Laboratory that was established in 2011 and has garnered significant grant support exceeding $10M. Nationally he is a leader in microsurgery, ethics, evidence based orthopaedics, and nanotechnology-based surgical research; serves in leadership roles for orthopaedic and spine societies (North American Spine Society, American Orthopaedic Association, etc.); and is an Editor for the highest impact factor journals in his field. He has published over 230 papers, editorials, and book chapters; is currently completing two monographs; and has presented over 200 times nationally and internationally including keynote addresses and visiting professorships.

Description of Research

Dr. Weiner's research interests focus largely on the application of new technologies to orthopedic surgery and outcomes research. In his laboratory-based efforts, Dr. Weiner is now leading a collaborative effort to apply nanotechnologies to orthopedic and spinal pathologies.

Areas Of Expertise

Nanotechnology Orthopedic surgery Spinal surgery
Education & Training

Residency, Summa Health System
MD, Northeastern Ohio Universities College of Medicine
Publications

Osteogenesis in the presence of chemotherapy: A biomimetic approach: Journal of Tissue Engineering
Brozovich, AA, Lenna, S, Paradiso, F, Serpelloni, S, McCulloch, P, Weiner, B, Yustein, JT & Taraballi, F 2022, , Journal of Tissue Engineering, vol. 13, pp. 20417314221138945. https://doi.org/10.1177/20417314221138945

Comparison Between Cancellous Trabecular and Cortical Specimens from Human Lumbar Spine Samples as an Alternative Source of Mesenchymal Stromal Cells
Lenna, S, Brozovich, A, Hirase, T, Paradiso, F, Weiner, BK & Taraballi, F 2022, , Stem Cells and Development, vol. 31, no. 21-22, pp. 672-683. https://doi.org/10.1089/scd.2022.0157

Comparison Between Cancellous Trabecular and Cortical Specimens from Human Lumbar Spine Samples as an Alternative Source of Mesenchymal Stromal Cells
Lenna, S, Brozovich, A, Hirase, T, Paradiso, F, Weiner, BK & Taraballi, F 2022, , Stem Cells and Development, vol. 31, no. 21-22, pp. 672-683. https://doi.org/10.1089/scd.2022.0157

Instrumented Versus Noninstrumented Spinal Fusion for Degenerative Lumbar Spondylolisthesis: A Systematic Review
Hirase, T, Ling, JF, Haghshenas, V & Weiner, BK 2022, , Clinical Spine Surgery, vol. 35, no. 5, pp. 213-221. https://doi.org/10.1097/BSD.0000000000001266

Analysis of Current Orthopedic Surgery Residents and Their Prior Medical Education: Does Medical School Ranking Matter in Orthopedic Surgery Match?
Holderread, BM, Liu, J, Craft, HK, Weiner, BK, Harris, JD & Liberman, SR 2022, , Journal of Surgical Education, vol. 79, no. 4, pp. 1063-1075. https://doi.org/10.1016/j.jsurg.2022.02.004

Osteogenesis in the presence of chemotherapy: A biomimetic approach
Brozovich, AA, Lenna, S, Paradiso, F, Serpelloni, S, McCulloch, P, Weiner, B, Yustein, JT & Taraballi, F 2022, , Journal of Tissue Engineering, vol. 13. https://doi.org/10.1177/20417314221138945

A CNN-based method to reconstruct 3-D spine surfaces from US images in vivo
Tang, S, Yang, X, Shajudeen, P, Sears, C, Taraballi, F, Weiner, B, Tasciotti, E, Dollahon, D, Park, H & Righetti, R 2021, , Medical Image Analysis, vol. 74, 102221. https://doi.org/10.1016/j.media.2021.102221

Improved Posterolateral Lumbar Spinal Fusion Using a Biomimetic, Nanocomposite Scaffold Augmented by Autologous Platelet-Rich Plasma
Van Eps, JL, Fernandez-Moure, JS, Cabrera, FJ, Taraballi, F, Paradiso, F, Minardi, S, Wang, X, Aghdasi, B, Tasciotti, E & Weiner, BK 2021, , Frontiers in Bioengineering and Biotechnology, vol. 9, 622099. https://doi.org/10.3389/fbioe.2021.622099

Platelet-rich plasma enhances mechanical strength of strattice in rat model of ventral hernia repair
Fernandez-Moure, JS, Van Eps, JL, Scherba, JC, Yazdi, IK, Robbins, A, Cabrera, F, Vatsaas, C, Moreno, M, Weiner, BK & Tasciotti, E 2021, , Journal of Tissue Engineering and Regenerative Medicine, vol. 15, no. 7, pp. 634-647. https://doi.org/10.1002/term.3200

Biocompatible PLGA-mesoporous silicon microspheres for the controlled release of bmp-2 for bone augmentation
Minardi, S, Fernandez-Moure, JS, Fan, D, Murphy, MB, Yazdi, IK, Liu, X, Weiner, BK & Tasciotti, E 2020, , Pharmaceutics, vol. 12, no. 2, 118. https://doi.org/10.3390/pharmaceutics12020118

Addition of platelet-rich plasma supports immune modulation and improved mechanical integrity in Alloderm mesh for ventral hernia repair in a rat model
Fernandez-Moure, JS, Van Eps, JL, Scherba, JC, Yazdi, IK, Robbins, A, Cabrera, F, Vatsaas, CJ, Moreno, M, Weiner, BK & Tasciotti, E 2021, , Journal of Tissue Engineering and Regenerative Medicine, vol. 15, no. 1, pp. 3-13. https://doi.org/10.1002/term.3156

Biomimetic hydroxyapatite/collagen composite drives bone niche recapitulation in a rabbit orthotopic model
Minardi, S, Taraballi, F, Cabrera, FJ, Van Eps, J, Wang, X, Gazze, SA, Fernandez-Mourev, JS, Tampieri, A, Francis, L, Weiner, BK & Tasciotti, E 2019, , Materials Today Bio, vol. 2, 100005. https://doi.org/10.1016/j.mtbio.2019.100005

Immune tuning scaffold for the local induction of a pro-regenerative environment
Corradetti, B, Taraballi, F, Corbo, C, Cabrera, F, Pandolfi, L, Minardi, S, Wang, X, Van Eps, J, Bauza, G, Weiner, B & Tasciotti, E 2017, , Scientific Reports, vol. 7, no. 1, 17030. https://doi.org/10.1038/s41598-017-16895-0

Bone-anchored annular closure following lumbar discectomy reduces risk of complications and reoperations within 90 days of discharge
Klassen, PD, Bernstein, DT, Köhler, HP, Arts, MP, Weiner, B, Miller, LE & Thomé, C 2017, , Journal of Pain Research, vol. 10, pp. 2047-2055. https://doi.org/10.2147/JPR.S144500

Characterization of ventral incisional hernia and repair using shear wave elastography
Chaudhry, A, Fernandez-Moure, JS, Shajudeen, PS, Van Eps, JL, Cabrera, FJ, Weiner, BK, Dunkin, BJ, Tasciotti, E & Righetti, R 2017, , Journal of Surgical Research, vol. 210, pp. 244-252. https://doi.org/10.1016/j.jss.2016.11.041

Platelet-rich plasma: a biomimetic approach to enhancement of surgical wound healing
Fernandez-Moure, JS, Van Eps, JL, Cabrera, FJ, Barbosa, Z, Medrano del Rosal, G, Weiner, BK, Ellsworth, WA & Tasciotti, E 2017, , Journal of Surgical Research, vol. 207, pp. 33-44. https://doi.org/10.1016/j.jss.2016.08.063

Cross-linking of porcine acellular dermal matrices negatively affects induced neovessel formation using platelet-rich plasma in a rat model of hernia repair
Fernandez-Moure, JS, Van Eps, JL, Peterson, LE, Shirkey, BA, Menn, ZK, Cabrera, F, Karim, A, Tasciotti, E, Weiner, BK & Ellsworth, WA 2017, , Wound Repair and Regeneration. https://doi.org/10.1111/wrr.12508

Biomimetic collagen/elastin meshes for ventral hernia repair in a rat model
Minardi, S, Taraballi, F, Wang, X, Cabrera, FJ, Van Eps, JL, Robbins, AB, Sandri, M, Moreno, MR, Weiner, BK & Tasciotti, E 2016, , Acta Biomaterialia. https://doi.org/10.1016/j.actbio.2016.11.032

To the Editor: Re: Singh K, Fineberg S, et al. Prospective, randomized, controlled trial of silicate-substituted calcium phosphate versusrhBMP-2 in a minimally invasive transforaminal lumbar interbody fusion Retraction. Spine 41(6); p553
Weiner, BK & Vargo, PE 2016, , Spine, vol. 41, no. 17, pp. E1069. https://doi.org/10.1097/BRS.0000000000001788

Response to the Letter to the Editor:
Weiner, BK 2016, , Spine, vol. 41, no. 17, pp. E1070. https://doi.org/10.1097/BRS.0000000000001787