Alberto Ayala, MD

Professor of Pathology and Genomic Medicine, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Shortly after completing a pathology fellowship at the MD Anderson Cancer Center in 1968, he joined the faculty there as an Assistant Professor. He stayed at the institution for 33 years, rising quickly through the academic ranks and earning numerous awards and accolades, including the Charles A. LeMaistre, MD Outstanding Achievement Award in Cancer. Dr. Ayala also held several leadership positions there, including Director of Surgical Pathology, Deputy Chairman of the Department of Anatomic Pathology, and Interim Head of the Division of Pathology. He assumed his current positions at Houston Methodist in 2004.

Description of Research

Dr. Ayala’s research focuses on the pathogenesis of carcinomas of the lung, kidneys and ovaries.

 

 

Areas Of Expertise

Carcinoma Lung Renal
Publications

Clinical presentation of ductal carcinoma in situ of breast with intraluminal crystalloids: Radiologic-histologic correlation
Jung, M, Maldonado, J, Schwartz, MR, Sneige, N, Ayala, AG & Ro, JY 2018, Annals of Diagnostic Pathology, vol. 37, pp. 42-46. DOI: 10.1016/j.anndiagpath.2018.09.001

Gastric mucinous carcinoma with micropapillary carcinoma component: Case report of tumor morphology not previously described in stomach
El-Zaatari, ZM, Schwartz, MR, Ayala, AG & Ro, JY 2018, Human Pathology: Case Reports, vol. 14, pp. 65-68. DOI: 10.1016/j.ehpc.2018.08.002

Flat epithelial atypia in directional vacuum-assisted biopsy of breast microcalcifications: surgical excision may not be necessary
McCroskey, Z, Sneige, N, Herman, CR, Miller, RA, Venta, LA, Ro, JY, Schwartz, MR & Ayala, AG 2018, Modern Pathology, pp. 1-10. DOI: 10.1038/s41379-018-0035-5

Renal collision tumor composed of oncocytoma and mucinous tubular and spindle cell carcinoma: case report of an unprecedented entity
Arora, K, Miller, R, Mullick, S, Shen, S, Ayala, AG & Ro, JY 2018, Human Pathology, vol. 71, pp. 60-64. DOI: 10.1016/j.humpath.2017.08.012

Sarcoid-like granulomas in renal cell carcinoma: The Houston Methodist Hospital experience
Arora, K, Divatia, MK, Truong, L, Shen, SS, Ayala, AG & Ro, JY 2017, Annals of Diagnostic Pathology, vol. 31, pp. 62-65. DOI: 10.1016/j.anndiagpath.2017.07.003

Prostatic adenocarcinoma in the setting of persistent müllerian duct syndrome: a case report
McCroskey, Z, Koen, TM, Lim, DJ, Divatia, MK, Shen, SS, Ayala, AG & Ro, JY 2018, Human pathology, vol. 75, pp. 125-131. DOI: 10.1016/j.humpath.2017.10.033

Primary collision tumors of the kidney composed of oncocytoma and papillary renal cell carcinoma: A review
McCroskey, Z, Sim, SJ, Selzman, AA, Ayala, AG & Ro, JY 2017, Annals of Diagnostic Pathology, vol. 29, pp. 32-36. DOI: 10.1016/j.anndiagpath.2017.04.011

Human colors-the rainbow garden of pathology: What gives normal and pathologic tissues their color?
Pina-Oviedo, S, Ortiz-Hidalgo, C & Ayala, AG 2017, Archives of Pathology and Laboratory Medicine, vol. 141, no. 3, pp. 445-462. DOI: 10.5858/arpa.2016-0274-SA

An isolated inflammatory myofibroblastic tumor of adrenal gland
Al Sannaa, G, Wimmer, JL, Ayala, AG & Ro, JY 2016, Annals of Diagnostic Pathology, vol. 25, pp. 33-36. DOI: 10.1016/j.anndiagpath.2016.04.011

Collagenous micronodules in prostate cancer revisited: Are they solely associated with Gleason pattern 3 adenocarcinomas?
Kim, MJ, Divatia, MK, Lee, JH, Shen, S, Miles, BJ, Hwang, JH, Ayala, AG & Ro, JY 2015, International Journal of Clinical and Experimental Pathology, vol. 8, no. 4, pp. 3469-3476.

Adenoid cystic carcinoma of breast: Recent advances
Miyai, K, Schwartz, MR, Divatia, MK, Anton, RC, Park, YW, Ayala, AG & Ro, JY 2014, World Journal of Clinical Cases, vol. 2, no. 12, pp. 732-41. DOI: 10.12998/wjcc.v2.i12.732

Sclerosing mucoepidermoid carcinoma with eosinophilia of the thyroid: more aggressive than previously reported
Quiroga-Garza, G, Lee, JHY, El-Naggar, A, Black, JO, Amrikachi, M, Zhai, QJ, Ayala, AG & Ro, JY 2015, Human Pathology, vol. 46, no. 5, pp. 725-731. DOI: 10.1016/j.humpath.2015.01.012

Metastasizing leiomyoma to heart
Consamus, EN, Reardon, MJ, Ayala, AG, Schwartz, MR & Ro, JY 2014, Methodist Debakey Cardiovascular Journal, vol. 10, no. 4, pp. 251-254. DOI: 10.14797/mdcj-10-4-251

Seminal vesicle intraepithelial involvement by prostate cancer: putative mechanism and clinicopathological significance
Miyai, K, Kristiansen, A, Egevad, L, Pina-Oviedo, S, Divatia, MK, Shen, SS, Miles, BJ, Ayala, AG, Park, YW & Ro, JY 2014, Human Pathology. DOI: 10.1016/j.humpath.2014.05.004

Intraoperative frozen section evaluation of ureteral and urethral margins: studies of 203 consecutive radical cystoprostatectomy for men with bladder urothelial carcinoma
Zhou, H, Ro, JY, Truong, LD, Ayala, AG & Shen, SS 2014, American Journal of Clinical and Experimental Urology, vol. 2, no. 2, pp. 156-60.

De novo large cell neuroendocrine carcinoma of the prostate gland with pelvic lymph node metastasis: A case report with review of literature
Okoye, E, Choi, EK, Divatia, M, Miles, BJ, Ayala, AG & Ro, JY 2014, International Journal of Clinical and Experimental Pathology, vol. 7, no. 12, pp. 9061-9066.

Calcified amorphous tumor of the heart: case report and review of the literature
Choi, EK, Ro, JY & Ayala, AG 2014, Methodist DeBakey Cardiovascular Journal, vol. 10, no. 1, pp. 38-40.

Heterogeneous clinicopathological features of intraductal carcinoma of the prostate: A comparison between 'precursor-like' and 'regular type' lesions
Miyai, K, Divatia, MK, Shen, SS, Miles, BJ, Ayala, AG & Ro, JY 2014, International Journal of Clinical and Experimental Pathology, vol. 7, no. 5, pp. 2518-2526.

Diagnostic utility of E-cadherin and P120 catenin cocktail immunostain in distinguishing DCIS from LCIS
Li, X, Schwartz, MR, Ro, J, Hamilton, CR, Ayala, AG, Truong, LD & Zhai, QJ 2014, International Journal of Clinical and Experimental Pathology, vol. 7, no. 5, pp. 2551-2557.

Clear cell papillary renal cell carcinoma is the fourth most common histologic type of renal cell carcinoma in 290 consecutive nephrectomies for renal cell carcinoma
Zhou, H, Zheng, S, Truong, LD, Ro, JY, Ayala, AG & Shen, SS 2014, Human Pathology, vol. 45, no. 1, pp. 59-64. DOI: 10.1016/j.humpath.2013.08.004