Alberto Ayala, MD

Professor of Pathology and Genomic Medicine, Academic Institute
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Shortly after completing a pathology fellowship at the MD Anderson Cancer Center in 1968, he joined the faculty there as an Assistant Professor. He stayed at the institution for 33 years, rising quickly through the academic ranks and earning numerous awards and accolades, including the Charles A. LeMaistre, MD Outstanding Achievement Award in Cancer. Dr. Ayala also held several leadership positions there, including Director of Surgical Pathology, Deputy Chairman of the Department of Anatomic Pathology, and Interim Head of the Division of Pathology. He assumed his current positions at Houston Methodist in 2004.

Description of Research

Dr. Ayala’s research focuses on the pathogenesis of carcinomas of the lung, kidneys and ovaries.

 

 

Areas Of Expertise

Carcinoma Lung Renal
Publications

Pleomorphic giant cell carcinoma of prostate: Rare tumor with unique clinicopathological, immunohistochemical, and molecular features
El-Zaatari, ZM, Thomas, JS, Divatia, MK, Shen, SS, Ayala, AG, Monroig-Bosque, P, Shehabeldin, A & Ro, JY 2021, , Annals of Diagnostic Pathology, vol. 52, 151719. https://doi.org/10.1016/j.anndiagpath.2021.151719

Extranodal Rosai-Dorfman disease involving soft tissue associated with increased IgG4 plasma cells
Thomas, KD, Delahoussaye, P, Schwartz, MR, Ayala, AG & Ro, JY 2021, , Human Pathology: Case Reports, vol. 24, 200488. https://doi.org/10.1016/j.ehpc.2021.200488

Leiomyoma of digit of hand: Report of three cases with literature review
Thomas, KD, Ro, JY & Ayala, AG 2021, , Annals of Diagnostic Pathology, vol. 50, 151669. https://doi.org/10.1016/j.anndiagpath.2020.151669

Seminal vesicle invasion combined with extraprostatic extension is associated with higher frequency of biochemical recurrence and lymph node metastasis than seminal vesicle invasion alone: Proposal for further pT3 prostate cancer subclassification
Rehman, A, El-Zaatari, ZM, Han, SH, Shen, SS, Ayala, AG, Miles, B, Divatia, MK, Ketcham, MS, Chung, BM, Rogers, JT & Ro, JY 2020, , Annals of Diagnostic Pathology, vol. 49, 151611. https://doi.org/10.1016/j.anndiagpath.2020.151611

Leiomyoadenomatoid Tumor of Epididymis: A Variant of Adenomatoid Tumor
Shehabeldin, A, Al Sannaa, G, El-Zaateri, Z, Andino, L, Schmolze, D, Chapman, D, Ayala, A & Ro, JY 2020, , Annals of clinical and laboratory science, vol. 50, no. 6, pp. 813-817.

Anastomosing hemangioma of the breast: An unusual case at an unusual site
Lin, MS, Ngo, T, Schwartz, MR, Mehta, RR, Ayala, AG & Ro, JY 2020, , Journal of Breast Cancer, vol. 23, no. 3, pp. 326-330. https://doi.org/10.4048/jbc.2020.23.e15

Monophasic epithelial synovial sarcoma initially diagnosed as metastatic adenocarcinoma of unknown primary
Baek, D, Barbieri, A, Ayala, AG, Lee, KM, Ju, MJ & Ro, JY 2019, , Human Pathology: Case Reports, vol. 17, 200307. https://doi.org/10.1016/j.hpcr.2019.200307

Micropapillary adenocarcinoma of lung: Morphological criteria and diagnostic reproducibility among pulmonary pathologists
Monroig-Bosque, PDC, Morales-Rosado, JA, Roden, AC, Churg, A, Barrios, R, Cagle, P, Ge, Y, Allen, TC, Smith, ML, Larsen, BT, Sholl, LM, Beasley, MB, Borczuk, A, Raparia, K, Ayala, A, Tazelaar, HD, Miller, R, Kalhor, N, Moran, CA & Ro, JY 2019, , Annals of Diagnostic Pathology, vol. 41, pp. 43-50. https://doi.org/10.1016/j.anndiagpath.2019.04.008

Solitary fibrous tumor of breast with anaplastic areas (Malignant solitary fibrous tumor): A case report with review of literature
Jung Jung, M, Alrahwan, D, Dubrovsky, E, Baek, D, Ayala, A & Ro, J 2019, , Journal of Breast Cancer, vol. 22, no. 2, pp. 326-335. https://doi.org/10.4048/jbc.2019.22.e30

Clear cell carcinoma of testis: A review
Lin, M, Awalt, H, Ayala, A & Ro, J 2019, , Annals of Diagnostic Pathology, vol. 40, pp. 26-29. https://doi.org/10.1016/j.anndiagpath.2019.03.002

Crystal storing histiocytosis: Unusual clinical presentations in two patients
Tomsula, J, Meis, JM, Koy, RD, Monheit, J, Zieske, A, Ro, J & Ayala, A 2019, , Annals of Diagnostic Pathology, vol. 40, pp. 13-17. https://doi.org/10.1016/j.anndiagpath.2019.01.003

Clinical presentation of ductal carcinoma in situ of breast with intraluminal crystalloids: Radiologic-histologic correlation
Jung, M, Maldonado, J, Schwartz, MR, Sneige, N, Ayala, A & Ro, J 2018, , Annals of Diagnostic Pathology, vol. 37, pp. 42-46. https://doi.org/10.1016/j.anndiagpath.2018.09.001

Gastric mucinous carcinoma with micropapillary carcinoma component: Case report of tumor morphology not previously described in stomach
El-Zaatari, ZM, Schwartz, MR, Ayala, AG & Ro, JY 2018, , Human Pathology: Case Reports, vol. 14, pp. 65-68. https://doi.org/10.1016/j.ehpc.2018.08.002

Flat epithelial atypia in directional vacuum-assisted biopsy of breast microcalcifications: surgical excision may not be necessary
McCroskey, Z, Sneige, N, Herman, CR, Miller, RA, Venta, LA, Ro, JY, Schwartz, MR & Ayala, AG 2018, , Modern Pathology, vol. 31, no. 7, pp. 1097-1106. https://doi.org/10.1038/s41379-018-0035-5

Renal collision tumor composed of oncocytoma and mucinous tubular and spindle cell carcinoma: case report of an unprecedented entity
Arora, K, Miller, R, Mullick, S, Shen, S, Ayala, AG & Ro, JY 2018, , Human Pathology, vol. 71, pp. 60-64. https://doi.org/10.1016/j.humpath.2017.08.012

Sarcoid-like granulomas in renal cell carcinoma: The Houston Methodist Hospital experience
Arora, K, Divatia, MK, Truong, L, Shen, S, Ayala, A & Ro, J 2017, , Annals of Diagnostic Pathology, vol. 31, pp. 62-65. https://doi.org/10.1016/j.anndiagpath.2017.07.003

Prostatic adenocarcinoma in the setting of persistent müllerian duct syndrome: a case report
McCroskey, Z, Koen, TM, Lim, DJ, Divatia, MK, Shen, SS, Ayala, AG & Ro, JY 2018, , Human Pathology, vol. 75, pp. 125-131. https://doi.org/10.1016/j.humpath.2017.10.033

Primary collision tumors of the kidney composed of oncocytoma and papillary renal cell carcinoma: A review
McCroskey, Z, Sim, SJ, Selzman, AA, Ayala, AG & Ro, JY 2017, , Annals of Diagnostic Pathology, vol. 29, pp. 32-36. https://doi.org/10.1016/j.anndiagpath.2017.04.011

Human colors-the rainbow garden of pathology: What gives normal and pathologic tissues their color?
Pina-Oviedo, S, Ortiz-Hidalgo, C & Ayala, AG 2017, , Archives of Pathology and Laboratory Medicine, vol. 141, no. 3, pp. 445-462. https://doi.org/10.5858/arpa.2016-0274-SA

An isolated inflammatory myofibroblastic tumor of adrenal gland
Al Sannaa, G, Wimmer, JL, Ayala, AG & Ro, JY 2016, , Annals of Diagnostic Pathology, vol. 25, pp. 33-36. https://doi.org/10.1016/j.anndiagpath.2016.04.011