After receiving her PhD in microbiology from the University of Paris, XI, in Paris, France, Dr. Rosato completed a postdoctoral fellowship in microbiology and infectious diseases at the University of Southern California and Children’s Hospital Los Angeles. She then completed a second fellowship at Virginia Commonwealth University in Richmond, VA, where she was the recipient of a prestigious National Research Service Award from the National Institutes of Health. Dr. Rosato remained at Virginia Commonwealth University after her postdoctoral training and became an assistant professor in the Department of Internal Medicine, Division of Infectious Diseases. She earned numerous honors while there, including the Faculty Award for Distinguished Research, and three faculty awards from the American Society of Microbiology for her mentoring of minority trainees. Dr. Rosato joined the Center for Molecular and Translational Human Infectious Diseases Research at the Houston Methodist Research Institute in 2010.
Multidrug resistant pathogens of clinical interests including , MRSA ( methicillin resistant S. aureus ) E.coli and Klebsiella pneumoniae.
My works in Infectious Diseases have extended for more than 24 years covering both aspects clinical, basic the translational aspects of related diseases. I have been conducting clinical and basic research on antimicrobials and multidrug-resistant (MDR) Gram-negative and Gram-positive bacterial pathogens to which treatment options are limited. My activities include as a group leader, pre-clinical and correlative clinical studies, writing protocols, presenting at scientific meetings and conferences developing collaborative relationships. I have a great deal of expertise in microbiology testing, molecular biology, diagnostics, genomic, transcriptomic analysis and in-vivo models. Moreover, working in close collaboration as advisor consultant of pharmaceutical companies/drug discovery, NIH-NIAID, and WHO division antimicrobial resistance. I am and have been involved in the discussion and decision of funding of USA and European agencies of clinical protocols. In addition, I have been contributing to the identification of antibacterial approaches and their execution, trained in areas of GCP, clinical trials, and CRO relationships. This extended experience has also helped me to grow as a scientist, mentor, and team leader, and making me better suited for the tasks as the evolution in the field requires.
Description of Research
Dr. Rosato's laboratory conducts translational research involving multidrug-resistant bacteria. Dr. Rosato's laboratory aim to identify the molecular genetic causes of drug resistance in MRSA. Data from these investigations could identify new therapeutic targets and aid in the development of novel antimicrobial agents. Her laboratory uses molecular biology techniques to understand the genetic basis of antimicrobial resistance and resistance gene spread among S. aureus cells.