Ashley M. Holder, MD

Houston Methodist Surgical Associates

Surgical Oncology General Surgery

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Phone: 713.441.5141


Smith Tower
6550 Fannin St.
Suite 1501
Houston, TX 77030

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Dr. Holder was born and raised in the Tampa Bay area where she developed a passion for fishing and playing piano. From an early age, she knew she did not want a career in the family accounting business, as she enjoyed biology and working with her hands. She moved to Houston after college to study at Baylor College of Medicine. After completing residency in St. Louis, she and her family returned to Houston, where she received specialized training in cancer surgery at MD Anderson Cancer Center. Dr. Holder values the diversity of people, activities, and culture in the Houston area. Although not a Texan by birth, she has embraced the welcoming and generous spirit of the state she now calls "home."
“As a surgeon, I owe it to my patients, who place their trust in me, to strive to exceed the standard of care, not only technically but also cognitively. My approach to caring for my patients is defined by my compassion to care for each patient as I would my own family.”
Clinical Interests:
  • Gastric cancer
  • Small bowel cancer
  • HIPEC (hyperthermic intraperitoneal chemotherapy)
  • Regional therapies
  • Peritoneal malignancies
  • Pseudomyxoma peritonei
  • Colorectal cancer
  • Appendiceal cancer
  • Melanoma
  • Merkel cell carcinoma
  • Sarcoma
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Education & Training

Board Certification: American Board of Surgery - General Surgery
Fellowship: University of Texas MD Anderson Cancer Center, Complex General Surgical Oncology - 2017
Residency: Washington University in St. Louis School of Medicine, General Surgery - 2015
Medical School: Baylor College of Medicine - 2008
Undergraduate: Davidson College - 2003
Board Certification: American Board of Surgery - Complex General Surgical Oncology - 2018
Languages Spoken

*Languages listed are spoken by doctor and/or office staff.
Office Locations
Smith Tower
6550 Fannin St.
Suite 1501
Houston, TX 77030
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Houston Methodist Hospital
6565 Fannin Street
Houston, TX 77030
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