Obstetrics and Gynecology Research

 

Houston Methodist’s Department of Obstetrics and Gynecology leads robust clinical research efforts with a focus on pivotal clinical trials, offered at regional locations to increase access to all patients. Our team collaborates with gynecological oncology clinical trial partners to forward the latest research in ovarian, uterine and cervical cancers.

 

Houston Methodist’s prioritization of research and education helps fast track critical studies. Our researchers are also making advancements in microbiome studies of the urogynecology tract, pelvic floor health and all aspects of urogynecology.

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Translational research cores facilitate moving preclinical discoveries into the clinical phase of development. Houston Methodist researchers are accelerating the discovery and delivery of better care by fostering new medical technologies and techniques using advanced imaging systems, minimal access technologies and robotics. Translational research cores also include the FAD compliant cGLP facilities designed to produce clinical grade radiopharmaceuticals, nanoparticles or biologicals for preclinical and clnical studies.

Goals
  • Develop novel technologies to enable less invasive medical care.
  • Demonstrate cutting-edge techniques via live audio and video conferencing within all Houston Methodist procedure areas.
  • Influence local, regional, national and international health care professionals and providers.
Goals
  • Develop novel technologies to enable less invasive medical care.
  • Demonstrate cutting-edge techniques via live audio and video conferencing within all Houston Methodist procedure areas.
  • Influence local, regional, national and international health care professionals and providers.
Objectives
  • Train physicians in procedural skills across multiple specialties.
  • Conduct research on the metrics of skills acquisition.
  • Enhance patient safety using high fidelity simulation training.
Approach
  • Practicing physicians can access all components under one roof.
  • Remote telementoring uses audiovisual conferencing via wearable technology.
  • Image guidance enhances procedural accuracy.
  • Robotics improve the efficacy and outcomes of minimally invasive procedures.

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Active Clinical Trials

22

GME Trainees

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Peer-Reviewed Publications in 2023
Clinical Trials
Open Clinical Trial: Endometrial Cancer
Testing addition of trastuzumab or trastuzumab/pertuzumab to usual chemotherapy for HER2 positive endometrial serous carcinoma or carcinosarcoma.
Open Clinical Trial: Endometrial Cancer
Selinexor in maintenance therapy after systemic therapy for patients with p53 wild-type, advanced or recurrent endometrial carcinoma.
Open Clinical Trial: LANCE Trial – Ovarian Cancer
Minimally invasive surgery after neoadjuvant chemotherapy for treatment of Stage IIIC-IV ovarian, primary peritoneal or fallopian tube cancer.
Open Clinical Trial: Ovarian Cancer
Safety, tolerability and efficacy of pembrolizumab/vibostolimab with or without other anticancer therapies in participants with selected solid tumors.

Upcoming Academic Events

Grand rounds, tumor boards, regularly scheduled series and case presentations are offered in multiple clinical disciplines and Houston Methodist locations.
2024 Fall NeuroSystems: From Circuits to Restoration
Houston Methodist Research Institute

Sep 18 @ 8AM

See Details
2024 National Postdoctoral Appreciation Week
Houston Methodist Research Institute

Sep 18 @ 10AM

See Details

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Grand Rounds conducted in 2023
These educational events are held according to varying schedules by departments and divisions within the Houston Methodist Academic Institute

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