Hegde lab Publications


Editorial: The self-renewal and reprogramming of cancer stem cells and their crosstalk with the immune microenvironment
Li, C, Rao, JK, Emani, LS, Kosagisharaf, RJ & Hegde, ML 2022, , Frontiers in Cell and Developmental Biology, vol. 10, 1024761, pp. 1024761. https://doi.org/10.3389/fcell.2022.1024761

Mitochondrial DNA damage-repair defects in mutant FUS-linked motor neuron diseases and its mitigation via targeted expression of DNA Ligase I
Wang, H, Kodavati, M, Guo, W, Mitra, J, Zhang, A, Mitra, S, Tomkinson, AE, Hamilton, DJ, Van Den Bosch, L & Hegde, M 2022, , 7th US-EU Conference on Endogenous DNA Damage and Repair, Newyork, United States, 11/6/22 - 11/9/22.

SARS-CoV-2 and the central nervous system: Emerging insights into hemorrhage-associated neurological consequences and therapeutic considerations
Mitra, J, Kodavati, M, Provasek, VE, Rao, KS, Mitra, S, Hamilton, DJ, Horner, PJ, Vahidy, FS, Britz, GW, Kent, TA & Hegde, ML 2022, , Ageing Research Reviews, vol. 80, 101687. https://doi.org/10.1016/j.arr.2022.101687

Pouteria sapota (Red Mamey Fruit): Chemistry and Biological Activity of Carotenoids
Lakey-Beitia, J, Vasquez, V, Mojica-Flores, R, Fuentes C. AL, Murillo, E, Hegde, ML & Rao, KS 2022, , Combinatorial Chemistry and High Throughput Screening, vol. 25, no. 7, pp. 1134-1147. https://doi.org/10.2174/1386207324666210301093711

DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders
Provasek, VE, Mitra, J, Malojirao, VH & Hegde, ML 2022, , International journal of molecular sciences, vol. 23, no. 9, 4653. https://doi.org/10.3390/ijms23094653

CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity
Guo, W, Wang, H, Kumar Tharkeshwar, A, Couthouis, J, Braems, E, Masrori, P, Van Schoor, E, Fan, Y, Ahuja, K, Moisse, M, Jacquemyn, M, Furtado Madeiro da Costa, R, Gajjar, M, Balusu, S, Tricot, T, Fumagalli, L, Hersmus, N, Janky, R, Impens, F, Vanden Berghe, P, Ho, R, Thal, DR, Vandenberghe, R, Hegde, ML, Chandran, S, De Strooper, B, Daelemans, D, Van Damme, P, Van Den Bosch, L & Verfaillie, C 2022, , Alzheimers and Dementia. https://doi.org/10.1002/alz.12760


A contemporary review of therapeutic and regenerative management of intracerebral hemorrhage
Sadaf, H, Desai, VR, Misra, V, Golanov, E, Hegde, ML, Villapol, S, Karmonik, C, Regnier-Golanov, A, Sayenko, D, Horner, PJ, Krencik, R, Weng, YL, Vahidy, FS & Britz, GW 2021, , Annals of Clinical and Translational Neurology. https://doi.org/10.1002/acn3.51443

Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
Bacolla, A, Sengupta, S, Ye, Z, Yang, C, Mitra, J, De-Paula, RB, Hegde, ML, Ahmed, Z, Mort, M, Cooper, DN, Mitra, S & Tainer, JA 2021, , Nucleic Acids Research, vol. 49, no. 1, pp. 221-243. https://doi.org/10.1093/nar/gkaa1120

Biopsychosocial intersections of social/affective touch and psychiatry: Implications of ‘touch hunger’ during COVID-19
Banerjee, D, Vasquez, V, Pecchio, M, Hegde, ML, Ks Jagannatha, R & Rao, TSS 2021, , International Journal of Social Psychiatry. https://doi.org/10.1177/0020764021997485

Computational Evaluation of Interaction between Curcumin Derivatives and Amyloid-ß Monomers and Fibrils: Relevance to Alzheimer's Disease
Orjuela, A, Lakey-Beitia, J, Mojica-Flores, R, Hegde, ML, Lans, I, Alí-Torres, J & Rao, KS 2021, , Journal of Alzheimers Disease, vol. 82, no. s1, pp. S321-S333. https://doi.org/10.3233/JAD-200941

Polyphenols as Potential Metal Chelation Compounds against Alzheimer's Disease
Lakey-Beitia, J, Burillo, AM, La Penna, G, Hegde, ML & Rao, KS 2021, , Journal of Alzheimers Disease, vol. 82, no. s1, pp. S335-S357. https://doi.org/10.3233/JAD-200185

A contemporary review of therapeutic and regenerative management of intracerebral hemorrhage
Sadaf, H, Desai, VR, Misra, V, Golanov, E, Hegde, ML, Villapol, S, Karmonik, C, Regnier-Golanov, A, Sayenko, D, Horner, PJ, Krencik, R, Weng, YL, Vahidy, FS & Britz, GW 2021, , Annals of Clinical and Translational Neurology, vol. 8, no. 11, pp. 2211-2221. https://doi.org/10.1002/acn3.51443, https://doi.org/10.1002/acn3.51443, https://doi.org/doi: 10.1002/acn3.51443

DNA damage and repair deficiency in ALS/FTD-associated neurodegeneration: from molecular mechanisms to therapeutic implication
Wang, H, Kodavati, M, Britz, GW & Hegde, M 2021, , Frontiers in Molecular Neuroscience.

The Chemical Basis of Intracerebral Hemorrhage and Cell Toxicity With Contributions From Eryptosis and Ferroptosis
Derry, PJ, Vo, ATT, Gnanansekaran, A, Mitra, J, Liopo, AV, Hegde, ML, Tsai, AL, Tour, JM & Kent, TA 2020, , Frontiers in Cellular Neuroscience, vol. 14, 603043. https://doi.org/10.3389/fncel.2020.603043

Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
Bacolla, A, Sengupta, S, Ye, Z, Yang, C, Mitra, J, De-Paula, RB, Hegde, ML, Ahmed, Z, Mort, M, Cooper, DN, Mitra, S & Tainer, JA 2020, , Nucleic Acids Research. https://doi.org/10.1093/nar/gkaa1120

Emerging Roles of Non-canonical RNA Binding Proteins in the Repair of Genome Damage Linked to Human Pathologies
Mitra, J, Wang, H, Kodavati, M, Mitra, S & Hegde, ML 2020, . in DNA Damage, DNA Repair and Disease: Volume 1. vol. 1, The Royal Society of Chemistry, United Kingdom, pp. 301-322. https://doi.org/10.1039/9781839160769-00301

Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin.
Hegde, M, Mitra, S, Sengupta, S, Bacolla, A, Ye, Z, Yang, C, Mitra, J, Tainer, JA & Ahmed, Z 2020, , Nucleic Acids Research.

Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription
Sengupta, S, Wang, H, Yang, C, Szczesny, B, Hegde, ML & Mitra, S 2020, , Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 36, pp. 22183-22192. https://doi.org/10.1073/pnas.1919445117

XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells
Eckelmann, BJ, Bacolla, A, Wang, H, Ye, Z, Guerrero, EN, Jiang, W, El-Zein, R, Hegde, ML, Tomkinson, AE, Tainer, JA & Mitra, S 2020, , NAR cancer, vol. 2, no. 3, pp. zcaa013. https://doi.org/10.1093/narcan/zcaa013