Hegde lab Publications
Editorial: The self-renewal and reprogramming of cancer stem cells and their crosstalk with the immune microenvironment
Li, C, Rao, JK, Emani, LS, Kosagisharaf, RJ & Hegde, ML 2022, , Frontiers in Cell and Developmental Biology, vol. 10, 1024761, pp. 1024761. https://doi.org/10.3389/fcell.2022.1024761
Mitochondrial DNA damage-repair defects in mutant FUS-linked motor neuron diseases and its mitigation via targeted expression of DNA Ligase I
Wang, H, Kodavati, M, Guo, W, Mitra, J, Zhang, A, Mitra, S, Tomkinson, AE, Hamilton, DJ, Van Den Bosch, L & Hegde, M 2022, , 7th US-EU Conference on Endogenous DNA Damage and Repair, Newyork, United States, 11/6/22 - 11/9/22.
SARS-CoV-2 and the central nervous system: Emerging insights into hemorrhage-associated neurological consequences and therapeutic considerations
Mitra, J, Kodavati, M, Provasek, VE, Rao, KS, Mitra, S, Hamilton, DJ, Horner, PJ, Vahidy, FS, Britz, GW, Kent, TA & Hegde, ML 2022, , Ageing Research Reviews, vol. 80, 101687. https://doi.org/10.1016/j.arr.2022.101687
Pouteria sapota (Red Mamey Fruit): Chemistry and Biological Activity of Carotenoids
Lakey-Beitia, J, Vasquez, V, Mojica-Flores, R, Fuentes C. AL, Murillo, E, Hegde, ML & Rao, KS 2022, , Combinatorial Chemistry and High Throughput Screening, vol. 25, no. 7, pp. 1134-1147. https://doi.org/10.2174/1386207324666210301093711
DNA Double-Strand Breaks as Pathogenic Lesions in Neurological Disorders
Provasek, VE, Mitra, J, Malojirao, VH & Hegde, ML 2022, , International journal of molecular sciences, vol. 23, no. 9, 4653. https://doi.org/10.3390/ijms23094653
CRISPR/Cas9 screen in human iPSC-derived cortical neurons identifies NEK6 as a novel disease modifier of C9orf72 poly(PR) toxicity
Guo, W, Wang, H, Kumar Tharkeshwar, A, Couthouis, J, Braems, E, Masrori, P, Van Schoor, E, Fan, Y, Ahuja, K, Moisse, M, Jacquemyn, M, Furtado Madeiro da Costa, R, Gajjar, M, Balusu, S, Tricot, T, Fumagalli, L, Hersmus, N, Janky, R, Impens, F, Vanden Berghe, P, Ho, R, Thal, DR, Vandenberghe, R, Hegde, ML, Chandran, S, De Strooper, B, Daelemans, D, Van Damme, P, Van Den Bosch, L & Verfaillie, C 2022, , Alzheimers and Dementia. https://doi.org/10.1002/alz.12760
DNA Damage and Repair Deficiency in ALS/FTD-Associated Neurodegeneration: From Molecular Mechanisms to Therapeutic Implication
Wang, H, Kodavati, M, Britz, GW & Hegde, M 2021, , Frontiers in Molecular Neuroscience, vol. 14, 784361. https://doi.org/10.3389/fnmol.2021.784361
A contemporary review of therapeutic and regenerative management of intracerebral hemorrhage
Sadaf, H, Desai, VR, Misra, V, Golanov, E, Hegde, ML, Villapol, S, Karmonik, C, Regnier-Golanov, A, Sayenko, D, Horner, PJ, Krencik, R, Weng, YL, Vahidy, FS & Britz, GW 2021, , Annals of Clinical and Translational Neurology. https://doi.org/10.1002/acn3.51443
Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
Bacolla, A, Sengupta, S, Ye, Z, Yang, C, Mitra, J, De-Paula, RB, Hegde, ML, Ahmed, Z, Mort, M, Cooper, DN, Mitra, S & Tainer, JA 2021, , Nucleic Acids Research, vol. 49, no. 1, pp. 221-243. https://doi.org/10.1093/nar/gkaa1120
Biopsychosocial intersections of social/affective touch and psychiatry: Implications of ‘touch hunger’ during COVID-19
Banerjee, D, Vasquez, V, Pecchio, M, Hegde, ML, Ks Jagannatha, R & Rao, TSS 2021, , International Journal of Social Psychiatry. https://doi.org/10.1177/0020764021997485
Computational Evaluation of Interaction between Curcumin Derivatives and Amyloid-ß Monomers and Fibrils: Relevance to Alzheimer's Disease
Orjuela, A, Lakey-Beitia, J, Mojica-Flores, R, Hegde, ML, Lans, I, Alí-Torres, J & Rao, KS 2021, , Journal of Alzheimers Disease, vol. 82, no. s1, pp. S321-S333. https://doi.org/10.3233/JAD-200941
Polyphenols as Potential Metal Chelation Compounds against Alzheimer's Disease
Lakey-Beitia, J, Burillo, AM, La Penna, G, Hegde, ML & Rao, KS 2021, , Journal of Alzheimers Disease, vol. 82, no. s1, pp. S335-S357. https://doi.org/10.3233/JAD-200185
A contemporary review of therapeutic and regenerative management of intracerebral hemorrhage
Sadaf, H, Desai, VR, Misra, V, Golanov, E, Hegde, ML, Villapol, S, Karmonik, C, Regnier-Golanov, A, Sayenko, D, Horner, PJ, Krencik, R, Weng, YL, Vahidy, FS & Britz, GW 2021, , Annals of Clinical and Translational Neurology, vol. 8, no. 11, pp. 2211-2221. https://doi.org/10.1002/acn3.51443, https://doi.org/10.1002/acn3.51443, https://doi.org/doi: 10.1002/acn3.51443
DNA damage and repair deficiency in ALS/FTD-associated neurodegeneration: from molecular mechanisms to therapeutic implication
Wang, H, Kodavati, M, Britz, GW & Hegde, M 2021, , Frontiers in Molecular Neuroscience.
The Chemical Basis of Intracerebral Hemorrhage and Cell Toxicity With Contributions From Eryptosis and Ferroptosis
Derry, PJ, Vo, ATT, Gnanansekaran, A, Mitra, J, Liopo, AV, Hegde, ML, Tsai, AL, Tour, JM & Kent, TA 2020, , Frontiers in Cellular Neuroscience, vol. 14, 603043. https://doi.org/10.3389/fncel.2020.603043
Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin
Bacolla, A, Sengupta, S, Ye, Z, Yang, C, Mitra, J, De-Paula, RB, Hegde, ML, Ahmed, Z, Mort, M, Cooper, DN, Mitra, S & Tainer, JA 2020, , Nucleic Acids Research. https://doi.org/10.1093/nar/gkaa1120
Emerging Roles of Non-canonical RNA Binding Proteins in the Repair of Genome Damage Linked to Human Pathologies
Mitra, J, Wang, H, Kodavati, M, Mitra, S & Hegde, ML 2020, . in DNA Damage, DNA Repair and Disease: Volume 1. vol. 1, The Royal Society of Chemistry, United Kingdom, pp. 301-322. https://doi.org/10.1039/9781839160769-00301
Heritable pattern of oxidized DNA base repair coincides with pre-targeting of repair complexes to open chromatin.
Hegde, M, Mitra, S, Sengupta, S, Bacolla, A, Ye, Z, Yang, C, Mitra, J, Tainer, JA & Ahmed, Z 2020, , Nucleic Acids Research.
Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription
Sengupta, S, Wang, H, Yang, C, Szczesny, B, Hegde, ML & Mitra, S 2020, , Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 36, pp. 22183-22192. https://doi.org/10.1073/pnas.1919445117
XRCC1 promotes replication restart, nascent fork degradation and mutagenic DNA repair in BRCA2-deficient cells
Eckelmann, BJ, Bacolla, A, Wang, H, Ye, Z, Guerrero, EN, Jiang, W, El-Zein, R, Hegde, ML, Tomkinson, AE, Tainer, JA & Mitra, S 2020, , NAR cancer, vol. 2, no. 3, pp. zcaa013. https://doi.org/10.1093/narcan/zcaa013