Center faculty opportunity:
The Center for Neuroregeneration at the Houston Methodist Research Institute led by Philip Horner, PhD, is a growing group of scientists and clinicians at the Houston Methodist Research Institute with the goal of creating new therapies for people with chronic neurologic injury. We currently seek faculty at the Assistant or Associate Professor level on the unmodified track (independent investigators). Responsibilities include establishing independent, extramurally funded research programs, supervising/mentoring lab personnel and interacting with the scientific community to develop translational research programs. State-of-the-art lab space and highly competitive start-up funds are available. We seek candidates who embrace and reflect diversity in the broadest sense.
Qualified candidates are expected to have expertise in neural engineering, brain-computer interfaces, next-generation electrode technologies or innovative physiology techniques to work with neurobiologists, stem cell biologists, bioengineers and clinicians at HMRI and throughout the Texas Medical Center.
· PhD in biomedical engineering, electrical engineering, physics, neuroscience, computer science or related fields.
· Experience in experimental brain interfaces, multi-electrode or optogenetics-based neurophysiology or other neural prosthetic applications is preferred.
· Novel engineering/biological aspects of neural plasticity that include electrode and circuit design, current steering, closed-loop control, neural interfacing and modeling is preferred.
· Neuroscience and machine learning/statistical/signal processing background.
· Experience working with human research subjects and/or animal subjects is preferred but not required.
· Expertise in the therapeutic applications of neuromodulation in neurological and neuropsychiatric conditions using systems neuroscience, modeling, and/or functional imaging techniques.
Please send Curriculum Vitae, statement of research interests and future objectives, and list of three references to Dee Woodson, Operations Manager at firstname.lastname@example.org.
We are always on the lookout for exceptional talent.
If you are interested in a graduate student opportunity, summer internship or in volunteering within any of the labs at the Center for Neuroregeneration, please write to specific laboratories listed below.
Neuroplasticity and Repair Lab:
The Horner Lab within the Center for Neuroregeneration focuses on the role of glial and neural progenitor cells in the regeneration of the injured and aging nervous system. Our laboratory seeks researchers to create cell and molecular tools for gene therapy, genetically engineer neural stem cells and assist with RNA and protein analyses in cell and animal studies. We are looking for research assistants and lab staff to utilizes skills to provide technical research laboratory support in performing research experiments, maintains records of data collected, assist in the organization, tabulation, and analysis of data. The ideal candidate will have educational and practical experience in neuroscience and/or neurobiology. Expertise is required in general cell/molecular biology including cell culture, cellular phenotyping, virus construction and production, gene transfection techniques, cloning, CRISPR editing, gene, and protein expression analysis. Please send Curriculum Vitae, statement of research interests and future objectives, and list of three references to Dr. Philip Horner at email@example.com
Astrocellular Therapeutics Lab:
The Astrocyte Research Lab is focused on utilizing multi-cellular brain and spinal cord circuits generated in our laboratory from human pluripotent stem cells in order to strategically address questions related to nervous response to post-injury environments and repair to restore functionality. Our goal is to uncover the signaling mechanisms activated in response to noxious extracellular stimuli as well as to devise strategies to alter this response. Interested candidates may write to Dr. Robert Krencik at firstname.lastname@example.org
The Neuromodulation and Recovery Laboratory:
The Sayenko lab is actively seeking individuals interested in human movement research and rehabilitation. Current projects are multidisciplinary and include the investigation of the effects and mechanisms of neuromodulation to promote functional recovery and mobility after neurological injuries and disorders, such as spinal cord injury or stroke.
The research coordinator will coordinate the research study and gather patient data for clinical research activities via methods specified in the study protocol and perform general administrative duties supporting the study. Preference will be given to applicants with prior research experience, particularly in motor control or neuromotor rehabilitation. Bachelor's or master's degree in biomedical engineering, neuroscience, kinesiology, or a related field is ideal. Must be able to work independently and with a team. Must be willing to learn how to operate the different software. Familiarity with EMG, motion capture/analysis, electrical or electromagnetic neurostimulation, MATLAB, and statistical methodology is preferred. Please send Curriculum Vitae, statement of research interests and future objectives, and list of three references to Dr. Sayenko at email@example.com
Brain Periphery Research Lab:
In the Villapol lab, we are investigating the contribution of peripheral inflammation, sex differences, and gut microbiota to brain pathology. Our overarching research goal is to provide a sound basis for developing novel therapies for patients suffering from a brain injury while performing exploratory research in the avenue of brain trauma and stroke. Our overall goal is to identify new treatments to restore the injured brain. Interested applicants should be skilled in general rodent models of brain injury (stroke, traumatic brain injury models, or similar), must have an ability to perform in vivo animal work, analyze data, and write and publish manuscripts. In addition, applicants must have excellent organizational and communication skills, with documented experience in molecular biology, rodent surgery. Experience in gnotobiotic mouse model systems and research experience utilizing rodents for behavioral assays is desired but not required. The candidate will have the opportunity to do basic science and pre-clinical research as they will work in a translational research environment. Please send Curriculum Vitae, statement of research interests and future objectives, and list of three references to Dr. Villapol at firstname.lastname@example.org
The Neuroepigenetics lab is interested in understanding how the regenerative capacity in multicellular organisms is governed in the nervous system after injury. We use combinatorial approaches including next-generation sequencing, molecular biology and fluorescence imaging to study the interaction between neural repair and human pathologies at different stages of development. In particular, we are interested in the m6A epitranscriptomic mechanisms regulating RNA trafficking, localization, and translation, as well as how dysfunction of these mechanisms could be linked to brain disorders. The long-term goal is to use knowledge obtained from these analyses to guide therapeutic approaches for treatment of injuries, stroke and neurodegenerative diseases. Please send Curriculum Vitae, statement of research interests and future objectives, and list of three references to Dr. Weng at email@example.com