Publications


AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate;
Gu, Q, Yang, X, Lv, J, Zhang, J, Xia, B, Kim, JD, Wang, R, Xiong, F, Meng, S, Clements, TP, Tandon, B, Wagner, DS, Diaz, MF, Wenzel, PL, Miller, YI, Traver, D, Cooke, JP, Li, W, Zon, LI, Chen, K, Bai, Y & Fang, L 2019, Science, pp. eaav1749. https://doi.org/10.1126/science.aav1749

Roles of the HOXA10 gene during castrate-resistant prostate cancer progression;
Long, Z, Li, Y, Gan, Y, Zhao, D, Wang, G, Xie, N, Lovnicki, JM, Fazli, L, Cao, Q, Chen, K & Dong, X 2019, Endocrine-Related Cancer, vol. 26, no. 3, pp. 279-292. https://doi.org/10.1530/ERC-18-0465

Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer;
Liu, Q, Wang, G, Li, Q, Jiang, W, Kim, JS, Wang, R, Zhu, S, Wang, X, Yan, L, Yi, Y, Zhang, L, Meng, Q, Li, C, Zhao, D, Qiao, Y, Li, Y, Gursel, DB, Chinnaiyan, AM, Chen, K & Cao, Q 2019, International Journal of Cancer. https://doi.org/10.1002/ijc.32118

Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks;
Yu, Y, Pham, N, Xia, B, Papusha, A, Wang, G, Yan, Z, Peng, G, Chen, K & Ira, G 2018, Nature, vol. 564, no. 7735, pp. 287-290. https://doi.org/10.1038/s41586-018-0769-8

TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway;
Meng, S, Gu, Q, Yang, X, Lv, J, Owusu, I, Matrone, G, Chen, K, Cooke, JP & Fang, L 2018, Circulation, vol. 138, no. 9, pp. 913-928. https://doi.org/10.1161/CIRCULATIONAHA.118.033939

Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan;
Hu, Z, Xia, B, Postnikoff, SDL, Shen, ZJ, Tomoiaga, AS, Harkness, TA, Seol, JH, Li, W, Chen, K & Tyler, JK 2018, eLife, vol. 7, e35551. https://doi.org/10.7554/eLife.35551

Homeobox oncogene activation by pan-cancer DNA hypermethylation;
Su, J, Huang, YH, Cui, X, Wang, X, Zhang, X, Lei, Y, Xu, J, Lin, X, Chen, K, Lv, J, Goodell, MA & Li, W 2018, Genome biology, vol. 19, no. 1, 108. https://doi.org/10.1186/s13059-018-1492-3

BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1;
Zhu, S, Zhao, D, Yan, L, Jiang, W, Kim, JS, Gu, B, Liu, Q, Wang, R, Xia, B, Zhao, JC, Song, G, Mi, W, Wang, RF, Shi, X, Lam, HM, Dong, X, Yu, J, Chen, K & Cao, Q 2018, Nature communications, vol. 9, no. 1, 500. https://doi.org/10.1038/s41467-018-02863-3

MeCP2 binds to non-CG methylated DNA as neurons mature, influencing transcription and the timing of onset for Rett syndrome;
Chen, L, Chen, K, Lavery, LA, Baker, SA, Shaw, CA, Li, W & Zoghbi, HY 2015, Proceedings of the National Academy of Sciences of the United States of America, vol. 112, no. 17, pp. 5509-5514. https://doi.org/10.1073/pnas.1505909112
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