Publications


Machine learning uncovers cell identity regulator by histone code;
Xia, B, Zhao, D, Wang, G, Zhang, M, Lv, J, Tomoiaga, AS, Li, Y, Wang, X, Meng, S, Cooke, JP, Cao, Q, Zhang, L & Chen, K 2020, Nature Communications, vol. 11, no. 1, 2696. https://doi.org/10.1038/s41467-020-16539-4

TADsplimer reveals splits and mergers of topologically associating domains for epigenetic regulation of transcription;
Wang, G, Meng, Q, Xia, B, Zhang, S, Lv, J, Zhao, D, Li, Y, Wang, X, Zhang, L, Cooke, JP, Cao, Q & Chen, K 2020, Genome Biology, vol. 21, no. 1, 84. https://doi.org/10.1186/s13059-020-01992-7

BMI1 is directly regulated by androgen receptor to promote castration-resistance in prostate cancer;
Zhu, S, Zhao, D, Li, C, Li, Q, Jiang, W, Liu, Q, Wang, R, Fazli, L, Li, Y, Zhang, L, Yi, Y, Meng, Q, Wang, W, Wang, G, Zhang, M, Zu, X, Zhao, W, Deng, T, Yu, J, Dong, X, Chen, K & Cao, Q 2020, Oncogene, vol. 39, no. 1, pp. 17-29. https://doi.org/10.1038/s41388-019-0966-4

Nuclear S-nitrosylation defines an optimal zone for inducing pluripotency;
Chanda, PK, Meng, S, Lee, J, Leung, HE, Chen, K & Cooke, JP 2019, Circulation, vol. 140, no. 13, pp. 1081-1099. https://doi.org/10.1161/CIRCULATIONAHA.119.042371

Polycomb group proteins EZH2 and EED directly regulate androgen receptor in advanced prostate cancer;
Liu, Q, Wang, G, Li, Q, Jiang, W, Kim, JS, Wang, R, Zhu, S, Wang, X, Yan, L, Yi, Y, Zhang, L, Meng, Q, Li, C, Zhao, D, Qiao, Y, Li, Y, Gursel, DB, Chinnaiyan, AM, Chen, K & Cao, Q 2019, , International Journal of Cancer, vol. 145, no. 2, pp. 415-426. https://doi.org/10.1002/ijc.32118

AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate;
Gu, Q, Yang, X, Lv, J, Zhang, J, Xia, B, Kim, JD, Wang, R, Xiong, F, Meng, S, Clements, TP, Tandon, B, Wagner, DS, Diaz, MF, Wenzel, PL, Miller, YI, Traver, D, Cooke, JP, Li, W, Zon, LI, Chen, K, Bai, Y & Fang, L 2019, , Science, pp. eaav1749. https://doi.org/10.1126/science.aav1749

Roles of the HOXA10 gene during castrate-resistant prostate cancer progression;
Long, Z, Li, Y, Gan, Y, Zhao, D, Wang, G, Xie, N, Lovnicki, JM, Fazli, L, Cao, Q, Chen, K & Dong, X 2019, , Endocrine-Related Cancer, vol. 26, no. 3, pp. 279-292. https://doi.org/10.1530/ERC-18-0465

Dna2 nuclease deficiency results in large and complex DNA insertions at chromosomal breaks;
Yu, Y, Pham, N, Xia, B, Papusha, A, Wang, G, Yan, Z, Peng, G, Chen, K & Ira, G 2018, , Nature, vol. 564, no. 7735, pp. 287-290. https://doi.org/10.1038/s41586-018-0769-8

TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway;
Meng, S, Gu, Q, Yang, X, Lv, J, Owusu, I, Matrone, G, Chen, K, Cooke, JP & Fang, L 2018, Circulation, vol. 138, no. 9, pp. 913-928. https://doi.org/10.1161/CIRCULATIONAHA.118.033939

Ssd1 and Gcn2 suppress global translation efficiency in replicatively aged yeast while their activation extends lifespan;
Hu, Z, Xia, B, Postnikoff, SDL, Shen, ZJ, Tomoiaga, AS, Harkness, TA, Seol, JH, Li, W, Chen, K & Tyler, JK 2018, , eLife, vol. 7, e35551. https://doi.org/10.7554/eLife.35551