Publications


Liposome-embedding silicon microparticle for oxaliplatin delivery in tumor chemotherapy
Cevenini, A, Celia, C, Orrù, S, Sarnataro, D, Raia, M, Mollo, V, Locatelli, M, Imperlini, E, Peluso, N, Peltrini, R, De Rosa, E, Parodi, A, Del Vecchio, L, Di Marzio, L, Fresta, M, Netti, PA, Shen, H, Liu, X, Tasciotti, E & Salvatore, F 2020, Pharmaceutics, vol. 12, no. 6, 559, pp. 1-28. https://doi.org/10.3390/pharmaceutics12060559

Sequential deconstruction of composite drug transport in metastatic breast cancer
Goel, S, Zhang, G, Dogra, P, Nizzero, S, Cristini, V, Wang, Z, Hu, Z, Li, Z, Liu, X, Shen, H & Ferrari, M 2020, Science advances, vol. 6, no. 26, eaba4498. https://doi.org/10.1126/sciadv.aba4498

Molecular targeting of FATP4 transporter for oral delivery of therapeutic peptide
Hu, Z, Nizzero, S, Goel, S, Hinkle, LE, Wu, X, Li, C, Ferrari, M & Shen, H 2020, Science advances, vol. 6, no. 14, eaba0145. https://doi.org/10.1126/sciadv.aba0145

Immunotherapeutic Transport Oncophysics: Space, Time, and Immune Activation in Cancer
Nizzero, S, Shen, H, Ferrari, M & Corradetti, B 2020, Trends in Cancer, vol. 6, no. 1, pp. 40-48. https://doi.org/10.1016/j.trecan.2019.11.008

Immunotherapeutic Transport Oncophysics: space, time, and immune activation against cancer.
Nizzero, S, Shen, H, Ferrari, M & Corradetti, B 2019, Trends in Cancer.

Systematic comparison of methods for determining the in vivo biodistribution of porous nanostructured injectable inorganic particles
Nizzero, S, Li, F, Zhang, G, Venuta, A, Borsoi, C, Mai, J, Shen, H, Wolfram, J, Li, Z, Blanco, E & Ferrari, M 2019, Acta Biomaterialia, vol. 97, pp. 501-512. https://doi.org/10.1016/j.actbio.2019.08.002

Vulnerable Atherosclerotic Plaque Imaging by Small-Molecule High-Affinity Positron Emission Tomography Radiopharmaceutical
Yang, Z, Li, F, Yelamanchili, D, Zeng, Z, Rosales, C, Youker, KA, Shen, H, Ferrari, M, Mahmarian, J, Pownall, HJ, Hamilton, DJ & Li, Z 2019, advanced therapeutics, vol. 2, no. 8. https://doi.org/10.1002/adtp.201900005

Investigation of parameters that determine Nano-DC vaccine transport
Zhang, J, Mai, J, Li, F, Shen, J, Zhang, G, Li, J, Hinkle, LE, Lin, D, Liu, X, Li, Z, Wang, R, Mittendorf, EA, Ferrari, M & Shen, H 2019, Biomedical Microdevices, vol. 21, no. 2, 39. https://doi.org/10.1007/s10544-019-0397-6

Tracking biodistribution of myeloid-derived cells in murine models of breast cancer
Li, J, Mai, J, Hinkle, L, Lin, D, Zhang, J, Liu, X, Ramirez, MR, Zu, Y, Lokesh, GL, Volk, DE & Shen, H 2019, Genes, vol. 10, no. 4, 297. https://doi.org/10.3390/genes10040297

PTGER3 induces ovary tumorigenesis and confers resistance to cisplatin therapy through up-regulation Ras-MAPK/Erk-ETS1-ELK1/CFTR1 axis
Rodriguez-Aguayo, C, Bayraktar, E, Ivan, C, Aslan, B, Mai, J, He, G, Mangala, LS, Jiang, D, Nagaraja, AS, Ozpolat, B, Chavez-Reyes, A, Ferrari, M, Mitra, R, Siddik, ZH, Shen, H, Yang, X, Sood, AK & Lopez-Berestein, G 2019, EBioMedicine, vol. 40, pp. 290-304. https://doi.org/10.1016/j.ebiom.2018.11.045

Chemotherapy sensitizes therapy-resistant cells to mild hyperthermia by suppressing heat shock protein 27 expression in triple-negative breast cancer
Mu, C, Wu, X, Zhou, X, Wolfram, J, Shen, J, Zhang, D, Mai, J, Xia, X, Holder, AM, Ferrari, M, Liu, X & Shen, H 2018, Clinical Cancer Research, vol. 24, no. 19, pp. 4900-4912. https://doi.org/10.1158/1078-0432.CCR-17-3872

Sensitizing non-small cell lung cancer to BCL-xL-targeted apoptosis
Shen, Q, Li, J, Mai, J, Zhang, Z, Fisher, A, Wu, X, Li, Z, Ramirez, MR, Chen, S & Shen, H 2018, Cell death & disease, vol. 9, no. 10, pp. 986. https://doi.org/10.1038/s41419-018-1040-9

SMAD4 gene mutation renders pancreatic cancer resistance to radiotherapy through promotion of autophagy
Wang, F, Xia, X, Yang, C, Shen, J, Mai, J, Kim, HC, Kirui, D, Kang, Y, Fleming, JB, Koay, EJ, Mitra, S, Ferrari, M & Shen, H 2018, Clinical Cancer Research, vol. 24, no. 13, pp. 3176-3185. https://doi.org/10.1158/1078-0432.CCR-17-3435

DNA Thioaptamer with Homing Specificity to Lymphoma Bone Marrow Involvement
Mai, J, Li, X, Zhang, G, Huang, Y, Xu, R, Shen, Q, Lokesh, GL, Thiviyanathan, V, Chen, L, Liu, H, Zu, Y, Ma, X, Volk, DE, Gorenstein, DG, Ferrari, M & Shen, H 2018, Molecular Pharmaceutics, vol. 15, no. 5, pp. 1814-1825. https://doi.org/10.1021/acs.molpharmaceut.7b01169

Pharmacological targeting of MYC-regulated IRE1/XBP1 pathway suppresses MYC-driven breast cancer
Zhao, N, Cao, J, Xu, L, Tang, Q, Dobrolecki, LE, Lv, X, Talukdar, M, Lu, Y, Wang, X, Hu, DZ, Shi, Q, Xiang, Y, Wang, Y, Liu, X, Bu, W, Jiang, Y, Li, M, Gong, Y, Sun, Z, Ying, H, Yuan, B, Lin, X, Feng, XH, Hartig, SM, Li, F, Shen, H, Chen, Y, Han, L, Zeng, Q, Patterson, JB, Kaipparettu, BA, Putluri, N, Sicheri, F, Rosen, JM, Lewis, MT & Chen, X 2018, Journal of Clinical Investigation, vol. 128, no. 4, pp. 1283-1299. https://doi.org/10.1172/JCI95873

Distribution of glutathione-stabilized gold nanoparticles in feline fibrosarcomas and their role as a drug delivery system for doxorubicin—preclinical studies in a murine model
Zabielska-Koczywas, K, Wojtalewicz, A, Uzarowska, E, Klejman, A, Wojtkowska, A, Dolka, I, Wojnicki, M, Sobczak, K, Wójcik, M, Shen, H, Ferrari, M & Lechowski, R 2018, International journal of molecular sciences, vol. 19, no. 4, 1021. https://doi.org/10.3390/ijms19041021

Cyclic cRGDfk peptide and Chlorin e6 functionalized silk fibroin nanoparticles for targeted drug delivery and photodynamic therapy
Mao, B, Liu, C, Zheng, W, Li, X, Ge, R, Shen, H, Guo, X, Lian, Q, Shen, X & Li, C 2018, Biomaterials, vol. 161, pp. 306-320. https://doi.org/10.1016/j.biomaterials.2018.01.045

Engineering functional inorganic-organic hybrid systems: Advances in siRNA therapeutics
Shen, J, Zhang, W, Qi, R, Mao, ZW & Shen, H 2018, Chemical Society Reviews, vol. 47, no. 6, pp. 1969-1995. https://doi.org/10.1039/c7cs00479f

Co-delivery of tumor antigen and dual toll-like receptor ligands into dendritic cell by silicon microparticle enables efficient immunotherapy against melanoma
Zhu, M, Ding, X, Zhao, R, Liu, X, Shen, H, Cai, C, Ferrari, M, Wang, HY & Wang, RF 2018, Journal of Controlled Release, vol. 272, pp. 72-82. https://doi.org/10.1016/j.jconrel.2018.01.004

A novel DNA aptamer for dual targeting of polymorphonuclear myeloid-derived suppressor cells and tumor cells
Liu, H, Mai, J, Shen, J, Wolfram, J, Li, Z, Zhang, G, Xu, R, Li, Y, Mu, C, Zu, Y, Li, X, Lokesh, GL, Thiviyanathan, V, Volk, DE, Gorenstein, DG, Ferrari, M, Hu, Z & Shen, H 2018, Theranostics, vol. 8, no. 1, pp. 31-44. https://doi.org/10.7150/thno.21342

Live Chat Available