Glioblastoma Research Lab
Professor of Neurosurgery
Director of Translational Research
Co-Director Radiosurgery Program
Houston Methodist Department of Neurological Surgery
Member, Houston Methodist Research Institute (HMRI)
Affiliate Professor, Weill Cornell School of Medicine
John S. “Steve” Dunn, Jr. & Dagmar Dunn Pickens Gipe Chair in Brain Tumor Research
Welcome aboard Shawn Brisbay
Targeting TWIST1 through loss of function inhibits tumorigenicity of human glioblastoma.
Mikheev AM, Mikheeva SA, Severs LJ, Funk CC, Huang L, McFaline-Figueroa JL, Schwensen J, Trapnell C, Price ND, Wong S, Rostomily RC. Mol Oncol. 2018 Jun;12(7):1188-1202.
An anatomic transcriptional atlas of human glioblastoma.
Puchalski RB, Shah N, Miller J, Dalley R, Nomura SR, Yoon JG, Smith KA, Lankerovich M, Bertagnolli D, Bickley K, Boe AF, Brouner K, Butler S, Caldejon S, Chapin M, Datta S, Dee N, Desta T, Dolbeare T, Dotson N, Ebbert A, Feng D, Feng X, Fisher M, Gee G, Goldy J, Gourley L, Gregor BW, Gu G, Hejazinia N, Hohmann J, Hothi P, Howard R, Joines K, Kriedberg A, Kuan L, Lau C, Lee F, Lee H, Lemon T, Long F, Mastan N, Mott E, Murthy C, Ngo K, Olson E, Reding M, Riley Z, Rosen D, Sandman D, Shapovalova N, Slaughterbeck CR, Sodt A, Stockdale G, Szafer A, Wakeman W, Wohnoutka PE, White SJ, Marsh D, Rostomily RC, Ng L, Dang C, Jones A, Keogh B, Gittleman HR, Barnholtz-Sloan JS, Cimino PJ, Uppin MS, Keene CD, Farrokhi FR, Lathia JD, Berens ME, Iavarone A, Bernard A, Lein E, Phillips JW, Rostad SW, Cobbs C, Hawrylycz MJ, Foltz GD. Science. 2018 May 11;360(6389):660-663.
Post-doctoral fellowships: The lab is actively interviewing for 1-2 postdoctoral positions to support ongoing projects involving i) mechanisms of Twist1 function in GBM and ii) optimization of primary patient derived GBM organotypic slice culture and tissue engineered cultures as platforms for preclinical screening on a microfluidic drug delivery platform. One position will be a named fellowship supported through the John S. “Steve” Dunn, Jr. & Dagmar Dunn Pickens Gipe Chair in Brain Tumor Research.
Research Assistants: We currently seek a research assistant with experience in the following areas: molecular and cell biology, animal colony management, immunohistochemistry/histology, laser capture microdissection.