Publications


Systematic Three-Dimensional Coculture Rapidly Recapitulates Interactions between Human Neurons and Astrocytes
Krencik, R, Seo, K, van Asperen, JV, Basu, N, Cvetkovic, C, Barlas, S, Chen, R, Ludwig, C, Wang, C, Ward, ME, Gan, L, Horner, PJ, Rowitch, DH & Ullian, EM 2017, Stem Cell Reports, vol 9, no. 6, pp. 1745-1753. DOI: 10.1016/j.stemcr.2017.10.026

Patient-derived iPSCs show premature neural differentiation and neuron type-specific phenotypes relevant to neurodevelopment
Yeh, E, Dao, DQ, Wu, ZY, Kandalam, SM, Camacho, FM, Tom, C, Zhang, W, Krencik, R, Rauen, KA, Ullian, EM & Weiss, LA 2017, Molecular Psychiatry. DOI: 10.1038/mp.2017.238

Human stem cell-derived astrocytes replicate human prions in a PRNP genotype-dependent manner
Krejciova, Z, Alibhai, J, Zhao, C, Krencik, R, Rzechorzek, NM, Ullian, EM, Manson, J, Ironside, JW, Head, MW & Chandran, S 2017, The Journal of experimental medicine, vol 214, no. 12, pp. 3481-3495. DOI: 10.1084/jem.20161547

Zika virus cell tropism in the developing human brain and inhibition by azithromycin
Retallack, H, Di Lullo, E, Arias, C, Knopp, KA, Laurie, MT, Sandoval-Espinosa, C, Mancia Leon, WR, Krencik, R, Ullian, EM, Spatazza, J, Pollen, AA, Mandel-Brehm, C, Nowakowski, TJ, Kriegstein, AR & DeRisi, JL 2016, Proceedings of the National Academy of Sciences of the United States of America, vol 113, no. 50, pp. 14408-14413. DOI: 10.1073/pnas.1618029113

Human astrocytes are distinct contributors to the complexity of synaptic function
Krencik, R, van Asperen, JV & Ullian, EM 2016, Brain Research Bulletin. DOI: 10.1016/j.brainresbull.2016.08.012

Directed differentiation of basal forebrain cholinergic neurons from human pluripotent stem cells
Hu, Y, Qu, Z-Y, Cao, S-Y, Li, Q, Ma, L, Krencik, R, Xu, M & Liu, Y 2016, Journal of Neuroscience Methods, vol 266, pp. 42-9. DOI: 10.1016/j.jneumeth.2016.03.017

Targeting brain’s star-shaped cells may yield autism drugs
Krencik, R, , 2016, Web publication/site.

Efficient generation of region-specific forebrain neurons from human pluripotent stem cells under highly defined condition
Yuan, F, Fang, K-H, Cao, S-Y, Qu, Z-Y, Li, Q, Krencik, R, Xu, M, Bhattacharyya, A, Su, Y-W, Zhu, D-Y & Liu, Y 2015, Scientific Reports, vol 5, pp. 18550. DOI: 10.1038/srep18550

Dysregulation of astrocyte extracellular signaling in Costello syndrome
Krencik, R, Hokanson, KC, Narayan, AR, Dvornik, J, Rooney, GE, Rauen, KA, Weiss, LA, Rowitch, DH & Ullian, EM 2015, Science Translational Medicine, vol 7, no. 286, pp. 286ra66. DOI: 10.1126/scitranslmed.aaa5645

Medial ganglionic eminence-like cells derived from human embryonic stem cells correct learning and memory deficits
Liu, Y, Weick, JP, Liu, H, Krencik, R, Zhang, X, Ma, L, Zhou, G, Ayala, M & Zhang, S-C 2013, Nature Biotechnology, vol 31, no. 5, pp. 440-7. DOI: 10.1038/nbt.2565

A cellular star atlas: using astrocytes from human pluripotent stem cells for disease studies
Krencik, R & Ullian, EM 2013, Frontiers in cellular neuroscience, vol 7, pp. 25. DOI: 10.3389/fncel.2013.00025

Astrocytes and disease: a neurodevelopmental perspectiv
Molofsky, AV, Krencik, R, Ullian, EM, Ullian, E, Tsai, H, Deneen, B, Richardson, WD, Barres, BA & Rowitch, DH 2012, Genes & development, vol 26, no. 9, pp. 891-907. DOI: 10.1101/gad.188326.112

Directed differentiation of functional astroglial subtypes from human pluripotent stem cells
Krencik, R & Zhang, S-C 2011, Nature Protocols, vol 6, no. 11, pp. 1710-7. DOI: 10.1038/nprot.2011.405

Specification of transplantable astroglial subtypes from human pluripotent stem cells
Krencik, R, Weick, JP, Liu, Y, Zhang, Z-J & Zhang, S-C 2011, Nature Biotechnology, vol 29, no. 6, pp. 528-34. DOI: 10.1038/nbt.1877

The COOH-terminal domain of the JIL-1 histone H3S10 kinase interacts with histone H3 and is required for correct targeting to chromatin
Bao, X, Cai, W, Deng, H, Zhang, W, Krencik, R, Girton, J, Johansen, J & Johansen, KM 2008, The Journal of biological chemistry, vol 283, no. 47, pp. 32741-50. DOI: 10.1074/jbc.M806227200

Stem cell neural differentiation: A model for chemical biology
Krencik, R & Zhang, S-C 2006, Current Opinion in Chemical Biology, vol 10, no. 6, pp. 592-7. DOI: 10.1016/j.cbpa.2006.10.002

The JIL-1 kinase interacts with lamin Dm0 and regulates nuclear lamina morphology of Drosophila nurse cells
Bao, X, Zhang, W, Krencik, R, Deng, H, Wang, Y, Girton, J, Johansen, J & Johansen, KM 2005, Journal of Cell Science, vol 118, no. Pt 21, pp. 5079-87. DOI: 10.1242/jcs.02611

Distinct mechanisms of neurodegeneration induced by chronic complex I inhibition in dopaminergic and non-dopaminergic cells
Kweon, G-R, Marks, JD, Krencik, R, Leung, EH, Schumacker, PT, Hyland, K & Kang, UJ 2004, The Journal of biological chemistry, vol 279, no. 50, pp. 51783-92. DOI: 10.1074/jbc.M407336200