Publications


Targeting USP7 identifies a metastasis-competent state within bone marrow–resident melanoma CTCs
Vishnoi, M, Boral, D, Liu, H, Sprouse, ML, Yin, W, Goswami-Sewell, D, Tetzlaff, MT, Davies, MA, Glitza Oliva, IC & Marchetti, D 2018, Cancer Research, vol. 78, no. 18, pp. 5249-5262. DOI: 10.1158/0008-5472.CAN-18-0644


Molecular characterization of breast cancer CTCs associated with brain metastasis
Boral, D, Vishnoi, M, Liu, HN, Yin, W, Sprouse, ML, Scamardo, A, Hong, DS, Tan, TZ, Thiery, JP, Chang, JC & Marchetti, D 2017, Nature Communications, vol. 8, no. 1, 196. DOI: 10.1038/s41467-017-00196-1

HN1L Promotes Triple-Negative Breast Cancer Stem Cells through LEPR-STAT3 Pathway
Liu, Y, Choi, DS, Sheng, J, Ensor, JE, Liang, DH, Rodriguez-Aguayo, C, Polley, A, Benz, S, Elemento, O, Verma, A, Cong, Y, Wong, H, Qian, W, Li, Z, Granados-Principal, S, Lopez-Berestein, G, Landis, MD, Rosato, RR, Dave, B, Wong, S, Marchetti, D, Sood, AK & Chang, JC 2017, Stem Cell Reports. DOI: 10.1016/j.stemcr.2017.11.010

The isolation and characterization of CTC subsets related to breast cancer dormancy
Vishnoi, M, Peddibhotla, S, Yin, W, Scamardo, AT, George, GC, Hong, DS & Marchetti, D 2015, Scientific Reports, vol. 5, 17533. DOI: 10.1038/srep17533

Oncogenic role of Merlin/NF2 in glioblastoma
Guerrero, PA, Yin, W, Camacho, L & Marchetti, D 2015, Oncogene, vol. 34, no. 20, pp. 2621-30. DOI: 10.1038/onc.2014.185

Heparanase promotes tumor infiltration and antitumor activity of CAR-redirected T lymphocytes
Caruana, I, Savoldo, B, Hoyos, V, Weber, G, Liu, H, Kim, ES, Ittmann, MM, Marchetti, D & Dotti, G 2015, Nature Medicine, vol. 21, no. 5, pp. 524-529. DOI: 10.1038/nm.3833

Heparanase mediates a novel mechanism in lapatinib-resistant brain metastatic breast cancer
Zhang, L, Ngo, JA, Wetzel, MD & Marchetti, D 2015, Neoplasia (United States), vol. 17, no. 1, pp. 101-113. DOI: 10.1016/j.neo.2014.11.007

MicroRNA and Protein Profiling of Brain Metastasis Competent Cell-Derived Exosomes
Camacho, L, Guerrero, P & Marchetti, D 2013, PLoS ONE, vol. 8, no. 9, e73790. DOI: 10.1371/journal.pone.0073790

The identification and characterization of breast cancer CTCs competent for brain metastasis
Zhang, L, Ridgway, LD, Wetzel, MD, Ngo, J, Yin, W, Kumar, D, Goodman, JC, Groves, MD & Marchetti, D 2013, Science Translational Medicine, vol. 5, no. 180, 180ra48. DOI: 10.1126/scitranslmed.3005109

Heparanase-induced GEF-H1 signaling regulates the cytoskeletal dynamics of brain metastatic breast cancer cells
Ridgway, LD, Wetzel, MD, Ngo, JA, Erdreich-Epstein, A & Marchetti, D 2012, Molecular Cancer Research, vol. 10, no. 6, pp. 689-702. DOI: 10.1158/1541-7786.MCR-11-0534

Selection of brain metastasis-initiating breast cancer cells determined by growth on hard agar
Guo, L, Fan, D, Zhang, F, Price, JE, Lee, JS, Marchetti, D, Fidler, IJ & Langley, RR 2011, American Journal of Pathology, vol. 178, no. 5, pp. 2357-2366. DOI: 10.1016/j.ajpath.2011.01.047

Heparanase modulates Shh and Wnt3a signaling in human medulloblastoma cells
Ridgway, LD, Wetzel, MD & Marchetti, D 2011, Experimental and Therapeutic Medicine, vol. 2, no. 2, pp. 229-237. DOI: 10.3892/etm.2010.189

MicroRNA-1258 suppresses breast cancer brain metastasis by targeting heparanase
Zhang, L, Sullivan, PS, Goodman, JC, Gunaratne, PH & Marchetti, D 2011, Cancer Research, vol. 71, no. 3, pp. 645-654. DOI: 10.1158/0008-5472.CAN-10-1910

Modulation of GEF-H1 induced signaling by heparanase in brain metastatic melanoma cells
Ridgway, LD, Wetzel, MD & Marchetti, D 2010, Journal of Cellular Biochemistry, vol. 111, no. 5, pp. 1299-1309. DOI: 10.1002/jcb.22854

Epidermal growth factor-induced heparanase nucleolar localization augments DNA topoisomerase I activity in brain metastatic breast cancer
Zhang, L, Sullivan, P, Suyama, J & Marchetti, D 2010, Molecular Cancer Research, vol. 8, no. 2, pp. 278-290. DOI: 10.1158/1541-7786.MCR-09-0375

Cell surface heparan sulfate released by Heparanase promotes melanoma cell migration and angiogenesis
Roy, M & Marchetti, D 2009, Journal of Cellular Biochemistry, vol. 106, no. 2, pp. 200-209. DOI: 10.1002/jcb.22005

HIP/RPL29 antagonizes VEGF and FGF2 stimulated angiogenesis by interfering with HS-dependent responses
DSouza, S, Yang, W, Marchetti, D, Muir, C, Farach-Carson, MC & Carson, DD 2008, Journal of Cellular Biochemistry, vol. 105, no. 5, pp. 1183-1193. DOI: 10.1002/jcb.21899

Heparanase expression and activity influences chondrogenic and osteogenic processes during endochondral bone formation
Brown, AJ, Alicknavitch, M, DSouza, SS, Daikoku, T, Kirn-Safran, CB, Marchetti, D, Carson, DD & Farach-Carson, MC 2008, Bone, vol. 43, no. 4, pp. 689-699. DOI: 10.1016/j.bone.2008.05.022

Neurotrophin receptors and heparanase: A functional axis in human medulloblastoma invasion
Marchetti, D, Mrak, RE, Paulsen, DD & Sinnappah-Kang, ND 2007, Journal of Experimental and Clinical Cancer Research, vol. 26, no. 1, pp. 5-23.