Simpson lab Publications


Immune-Mediated Neuropathies
Fadia, M, Shroff, S & Greene, EP 2019, Current Treatment Options in Neurology, vol. 21, no. 6, 28. https://doi.org/10.1007/s11940-019-0569-y

Efficacy and safety of IVIG in CIDP: Combined data of the PRIMA and PATH studies
on Behalf of the PRIMA Trial Investigators and the PATH Study Group 2019, Journal of the Peripheral Nervous System, vol. 24, no. 1, pp. 48-55. https://doi.org/10.1111/jns.12302


Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial
The Rasagiline Investigators of the Muscle Study Group and Western ALS Consortium 2019, , Muscle and Nerve, vol. 59, no. 2, pp. 201-207. https://doi.org/10.1002/mus.26335

Consensus-based care recommendations for adults with myotonic dystrophy type 1
Ashizawa, T, Gagnon, C, Groh, WJ, Gutmann, L, Johnson, NE, Meola, G, Moxley, R, Pandya, S, Rogers, MT, Greene, EP, Angeard, N, Bassez, G, Berggren, KN, Bhakta, D, Bozzali, M, Broderick, A, Byrne, JLB, Campbell, C, Cup, E, Day, JW, De Mattia, E, Duboc, D, Duong, T, Eichinger, K, Ekstrom, AB, Van Engelen, B, Esparis, B, Eymard, B, Ferschl, M, Gadalla, SM, Gallais, B, Goodglick, T, Heatwole, C, Hilbert, J, Holland, V, Kierkegaard, M, Koopman, WJ, Lane, K, Maas, D, Mankodi, A, Mathews, KD, Monckton, DG, Moser, D, Nazarian, S, Nguyen, L, Nopoulos, P, Petty, R, Phetteplace, J, Puymirat, J, Raman, S, Richer, L, Roma, E, Sampson, J, Sansone, V, Schoser, B, Sterling, L, Statland, J, Subramony, SH, Tian, C, Trujillo, C, Tomaselli, G, Turner, C, Verma, A, White, M & Winblad, S 2018, , Neurology: Clinical Practice, vol. 8, no. 6, pp. 507-520. https://doi.org/10.1212/CPJ.0000000000000531

Neuroinflammatory mechanisms in amyotrophic lateral sclerosis pathogenesis
Thonhoff, JR, Simpson, EP & Appel, SH 2018, , Current opinion in neurology, vol. 31, no. 5, pp. 635-639. https://doi.org/10.1097/WCO.0000000000000599

Expanded autologous regulatory T-lymphocyte infusions in ALS A phase I, first-in-human study
Thonhoff, JR, Beers, DR, Zhao, W, Pleitez, M, Simpson, EP, Berry, JD, Cudkowicz, ME & Appel, SH 2018, , Neurology: Neuroimmunology and NeuroInflammation, vol. 5, no. 4, e465, pp. e465. https://doi.org/10.1212/NXI.0000000000000465

Expanded autologous regulatory T-lymphocyte infusions in ALS
Thonhoff, JR, Beers, DR, Zhao, W, Pleitez, M, Simpson, EP, Berry, JD, Cudkowicz, ME & Appel, SH 2018, Neurology - Neuroimmunology Neuroinflammation, vol. 5, no. 4.

Intravenous versus subcutaneous immunoglobulin – Authors' reply
PATH study group 2018, The Lancet Neurology, vol. 17, no. 5, pp. 393-394. https://doi.org/10.1016/S1474-4422(18)30109-1

Genome-wide Analyses Identify KIF5A as a Novel ALS Gene
ITALSGEN Consortium, Genomic Translation for ALS Care (GTAC) Consortium, ALS Sequencing Consortium, NYGC ALS Consortium, Answer ALS Foundation, Clinical Research in ALS and Related Disorders for Therapeutic Development (CReATe) Consortium, SLAGEN Consortium, French ALS Consortium & Project MinE ALS Sequencing Consortium 2018, Neuron, vol. 97, no. 6, pp. 1268-1283.e6. https://doi.org/10.1016/j.neuron.2018.02.027



Phase IIa trial of fingolimod for amyotrophic lateral sclerosis demonstrates acceptable acute safety and tolerability
Berry, JD, Paganoni, S, Atassi, N, Macklin, EA, Goyal, N, Rivner, M, Greene, EP, Appel, SH, Grasso, DL, Mejia, NI, Mateen, F, Gill, A, Vieira, F, Tassinari, V & Perrin, S 2017, , Muscle and Nerve, vol. 56, no. 6, pp. 1077-1084. https://doi.org/10.1002/mus.25733

Improving symptom management for people with amyotrophic lateral sclerosis
Nicholson, K, Murphy, A, Mcdonnell, E, Shapiro, J, Greene, EP, Glass, J, Mitsumoto, H, Forshew, D, Miller, R & Atassi, N 2017, , Muscle and Nerve. https://doi.org/10.1002/mus.25712

Neurologic complications of systemic disease
Eatman, JD & Greene, EP 2017, . in Neurology Secrets: Sixth Edition. Elsevier, pp. 336-352. https://doi.org/10.1016/B978-0-323-35948-1.00024-3

Myelopathies
Eatman, J & Greene, EP 2017, . in Neurology Secrets: Sixth Edition. Elsevier, pp. 103-113. https://doi.org/10.1016/B978-0-323-35948-1.00008-5

A randomized controlled trial of methotrexate for patients with generalized myasthenia gravis
Pasnoor, M, He, J, Herbelin, L, Burns, TM, Nations, S, Bril, V, Wang, AK, Elsheikh, BH, Kissel, JT, Saperstein, D, Shaibani, JA, Jackson, C, Swenson, A, Howard, JF, Goyal, N, David, W, Wicklund, M, Pulley, M, Becker, M, Mozaffar, T, Benatar, M, Pazcuzzi, R, Greene, EP, Rosenfeld, J, Dimachkie, MM, Statland, JM & Barohn, RJ 2016, , Neurology, vol. 87, no. 1, pp. 57-64. https://doi.org/10.1212/WNL.0000000000002795

Amyotrophic lateral sclerosis
Greene, EP & Appel, SH 2016, . in Neuroimmune Pharmacology. Springer International Publishing, pp. 493-502. https://doi.org/10.1007/978-3-319-44022-4_32

Exome sequencing in amyotrophic lateral sclerosis identifies risk genes and pathways
Cirulli, ET, Lasseigne, BN, Petrovski, S, Sapp, PC, Dion, PA, Leblond, CS, Couthouis, J, Lu, Y-F, Wang, Q, Krueger, BJ, Ren, Z, Keebler, J, Han, Y, Levy, SE, Boone, BE, Wimbish, JR, Waite, LL, Jones, AL, Carulli, JP, Day-Williams, AG, Staropoli, JF, Xin, WW, Chesi, A, Raphael, AR, McKenna-Yasek, D, Cady, J, Vianney de Jong, JMB, Kenna, KP, Smith, BN, Topp, S, Miller, J, Gkazi, A, Al-Chalabi, A, van den Berg, LH, Veldink, J, Silani, V, Ticozzi, N, Shaw, CE, Baloh, RH, Appel, S, Simpson, E, Lagier-Tourenne, C, Pulst, SM, Gibson, S, Trojanowski, JQ, Elman, L, McCluskey, L, Grossman, M, Shneider, NA, Chung, WK & FALS Sequencing Consortium 2015, Science (New York, N.Y.), vol. 347, no. 6229, pp. 1436-41. https://doi.org/10.1126/science.aaa3650

A multi-center screening trial of rasagiline in patients with amyotrophic lateral sclerosis: Possible mitochondrial biomarker target engagement
Macchi, Z, Wang, Y, Moore, D, Katz, J, Saperstein, D, Walk, D, Greene, EP, Genge, A, Bertorini, T, Fernandes, JA, Swenson, A, Elman, L, Dimachkie, M, Herbelin, L, Miller, J, Lu, J, Wilkins, H, Swerdlow, RH, Statland, J & Barohn, R 2015, , Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration, vol. 16, no. 5-6, pp. 345-352. https://doi.org/10.3109/21678421.2015.1026826