Musser lab Publications


Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence
Do, H, Makthal, N, Chandrangsu, P, Olsen, RJ, Helmann, JD, Musser, JM & Kumaraswami, M 2019, Nucleic Acids Research, vol. 47, no. 15, pp. 8333-8334. https://doi.org/10.1093/nar/gkz641

Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence
Do, H, Makthal, N, Chandrangsu, P, Olsen, RJ, Helmann, JD, Musser, JM & Kumaraswami, M 2019, Nucleic Acids Research, vol. 47, no. 14, pp. 7476-7493. https://doi.org/10.1093/nar/gkz524

Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway
Do, H, Makthal, N, VanderWal, AR, Saavedra, MO, Olsen, RJ, Musser, JM & Kumaraswami, M 2019, Nature Communications, vol. 10, no. 1, 2586. https://doi.org/10.1038/s41467-019-10556-8

Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis
Kachroo, P, Eraso, JM, Beres, SB, Olsen, RJ, Zhu, L, Nasser, W, Bernard, PE, Cantu, CC, Saavedra, MO, Arredondo, MJ, Strope, B, Do, H, Kumaraswami, M, Vuopio, J, Gröndahl-Yli-Hannuksela, K, Kristinsson, KG, Gottfredsson, M, Pesonen, M, Pensar, J, Davenport, ER, Clark, AG, Corander, J, Caugant, DA, Gaini, S, Magnussen, MD, Kubiak, SL, Nguyen, HAT, Long, SW, Porter, AR, DeLeo, FR & Musser, JM 2019, Nature Genetics, vol. 51, no. 3, pp. 548-559. https://doi.org/10.1038/s41588-018-0343-1

Gene fitness landscape of group A streptococcus during necrotizing myositis
Zhu, L, Olsen, RJ, Beres, SB, Eraso, JM, Saavedra, MO, Kubiak, SL, Cantu, CC, Jenkins, L, Charbonneau, ARL, Waller, AS & Musser, JM 2019, The Journal of clinical investigation, vol. 129, no. 2, pp. 887-901. https://doi.org/10.1172/JCI124994

Draft Genome Sequence of Candida auris Strain LOM, a Human Clinical Isolate from Greater Metropolitan Houston, Texas
Long, SW, Olsen, RJ, Nguyen, HAT, Saavedra, MO & Musser, JM 2019, Microbiology Resource Announcements, vol. 8, no. 25, e00532-19. https://doi.org/10.1128/MRA.00532-19

RocA Has Serotype-Specific Gene Regulatory and Pathogenesis Activities in Serotype M28 Group A Streptococcus
Bernard, PE, Kachroo, P, Zhu, L, Beres, SB, Eraso, JM, Kajani, Z, Long, SW, Musser, JM & Olsen, RJ 2018, Infection and immunity, vol. 86, no. 11, e00467-18. https://doi.org/10.1128/IAI.00467-18

Phenotypic Variation in the Group A Streptococcus Due to Natural Mutation of the Accessory Protein-Encoding Gene rocA
Sarkar, P, Danger, JL, Jain, I, Meadows, LA, Beam, C, Medicielo, J, Burgess, C, Musser, JM & Sumby, P 2018, mSphere, vol. 3, no. 5. https://doi.org/10.1128/mSphere.00519-18

Postpartum Group A Streptococcus Case Series: Reach Out to Infection Prevention!
Alexander, AJ, Myers, C, Beres, SB, Olsen, RJ, Musser, JM & Mangino, JE 2018, Open Forum Infectious Diseases, vol. 5, no. 7, pp. ofy159. https://doi.org/10.1093/ofid/ofy159

Signaling by a conserved quorum sensing pathway contributes to growth ex vivo and oropharyngeal colonization of human pathogen group A streptococcus
Makthal, N, Do, H, VanderWal, AR, Olsen, RJ, Musser, JM & Kumaraswami, M 2018, Infection and Immunity, vol. 86, no. 5, e00169-18. https://doi.org/10.1128/IAI.00169-18

Genome sequence analysis of emm89 Streptococcus pyogenes strains causing infections in Scotland, 2010–2016
Beres, SB, Olsen, RJ, Saavedra, MO, Ure, R, Reynolds, A, Lindsay, DSJ, Smith, AJ & Musser, JM 2017, Journal of Medical Microbiology, vol. 66, no. 12, 000622, pp. 1765-1773. https://doi.org/10.1099/jmm.0.000622

Developing an in silico minimum inhibitory concentration panel test for Klebsiella pneumonia
Nguyen, M, Brettin, T, Long, SW, Musser, JM, Olsen, RJ, Olson, R, Shukla, M, Stevens, RL, Xia, F, Yoo, H & Davis, JJ 2018, Scientific Reports, vol. 8, no. 1, 421. https://doi.org/10.1038/s41598-017-18972-w


Novel genes required for the fitness of Streptococcus pyogenes in human saliva
Zhu, L, Charbonneau, ARL, Waller, AS, Olsen, RJ, Beres, SB & Musser, JM 2017, mSphere, vol. 2, no. 6, e00460-17. https://doi.org/10.1128/mSphereDirect.00460-17

Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen
Do, H, Makthal, N, VanderWal, AR, Rettel, M, Savitski, MM, Peschek, N, Papenfort, K, Olsen, RJ, Musser, JM & Kumaraswami, M 2017, Proceedings of the National Academy of Sciences. https://doi.org/10.1073/pnas.1705972114

Increased pilus production conferred by a naturally occurring mutation alters hostpathogen interaction in favor of carriage in Streptococcus pyogenes
Flores, AR, Olsen, RJ, Cantu, C, Pallister, KB, Guerra, FE, Voyich, JM & Musser, JM 2017, Infection and Immunity, vol. 85, no. 5, e00949-16. https://doi.org/10.1128/IAI.00949-16

Rapid emergence of a new clone impacts the population at risk and increases the incidence of type emm89 group A Streptococcus invasive disease
Teatero, S, Coleman, BL, Beres, SB, Olsen, RJ, Kandel, C, Reynolds, O, Athey, TBT, Musser, JM, McGeer, A & Fittipaldi, N 2017, Open Forum Infectious Diseases, vol. 4, no. 2, ofx042. https://doi.org/10.1093/ofid/ofx042


Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis
Skwark, MJ, Croucher, NJ, Puranen, S, Chewapreecha, C, Pesonen, M, Xu, YY, Turner, P, Harris, SR, Beres, SB, Musser, JM, Parkhill, J, Bentley, SD, Aurell, E & Corander, J 2017, PLoS Genetics, vol. 13, no. 2, pp. e1006508. https://doi.org/10.1371/journal.pgen.1006508


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