Musser lab Publications


Streptococcus pyogenes genes that promote pharyngitis in primates
Zhu, L, Olsen, RJ, Beres, SB, Saavedra, MO, Kubiak, SL, Cantu, CC, Jenkins, L, Waller, AS, Sun, Z, Palzkill, T, Porter, AR, DeLeo, FR & Musser, JM 2020, JCI insight, vol. 5, no. 11. https://doi.org/10.1172/jci.insight.137686

Genetic evolution of invasive emm28 Streptococcus pyogenes strains and significant association with puerperal infections in young women in Finland
Gröndahl-Yli-Hannuksela, K, Beres, SB, Hyyryläinen, HL, Kallonen, T, Musser, JM & Vuopio, J 2020, Clinical Microbiology and Infection. https://doi.org/10.1016/j.cmi.2020.04.004

Genome-Wide Screens Identify Group A Streptococcus Surface Proteins Promoting Female Genital Tract Colonization and Virulence
Zhu, L, Olsen, RJ, Beres, SB, Ojeda Saavedra, M, Kubiak, SL, Cantu, CC, Jenkins, L, Yerramilli, P, Pruitt, L, Charbonneau, ARL, Waller, AS & Musser, JM 2020, American Journal of Pathology, vol. 190, no. 4, pp. 862-873. https://doi.org/10.1016/j.ajpath.2019.12.003

New pathogenesis mechanisms and translational leads identified by multidimensional analysis of necrotizing myositis in primates
Kachroo, P, Eraso, JM, Olsen, RJ, Zhu, L, Kubiak, SL, Pruitt, L, Yerramilli, P, Cantu, CC, Saavedra, MO, Pensar, J, Corander, J, Jenkins, L, Kao, L, Granillo, A, Porter, AR, Deleo, FR & Musser, JM 2020, mBio, vol. 11, no. 1, e03363-19. https://doi.org/10.1128/mBio.03363-19


Reduced in vitro susceptibility of streptococcus pyogenes to ß-lactam antibiotics associated with mutations in the pbp2x gene is geographically widespread
Musser, JM, Beres, SB, Zhu, L, Olsen, RJ, Vuopio, J, Hyyryläinen, HL, Gröndahl-Yli-Hannuksela, K, Kristinsson, KG, Darenberg, J, Henriques-Normark, B, Hoffmann, S, Caugant, DA, Smith, AJ, Lindsay, DSJ, Boragine, DM & Palzkill, T 2020, Journal of Clinical Microbiology, vol. 58, no. 4, e01993-19. https://doi.org/10.1128/JCM.01993-19

Genetic heterogeneity of the Spy1336/R28—Spy1337 virulence axis in Streptococcus pyogenes and effect on gene transcript levels and pathogenesis
Eraso, JM, Kachroo, P, Olsen, RJ, Beres, SB, Zhu, L, Badu, T, Shannon, S, Cantu, CC, Saavedra, MO, Kubiak, SL, Porter, AR, DeLeo, FR & Musser, JM 2020, PloS one, vol. 15, no. 3, e0229064. https://doi.org/10.1371/journal.pone.0229064

FASEB 2019: Current Topics in Science Advocacy and Policy
Musser, JM 2019, Journal of biomolecular techniques : JBT, vol. 30, pp. S49-S50.

Polymorphisms in Regulator of Cov Contribute to the Molecular Pathogenesis of Serotype M28 Group A Streptococcus
Bernard, PE, Kachroo, P, Eraso, JM, Zhu, L, Madry, JE, Linson, SE, Ojeda Saavedra, M, Cantu, C, Musser, JM & Olsen, RJ 2019, American Journal of Pathology, vol. 189, no. 10, pp. 2002-2018. https://doi.org/10.1016/j.ajpath.2019.06.009

Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence
Do, H, Makthal, N, Chandrangsu, P, Olsen, RJ, Helmann, JD, Musser, JM & Kumaraswami, M 2019, Nucleic Acids Research, vol. 47, no. 15, pp. 8333-8334. https://doi.org/10.1093/nar/gkz641

Metal sensing and regulation of adaptive responses to manganese limitation by MtsR is critical for group A streptococcus virulence
Do, H, Makthal, N, Chandrangsu, P, Olsen, RJ, Helmann, JD, Musser, JM & Kumaraswami, M 2019, Nucleic Acids Research, vol. 47, no. 14, pp. 7476-7493. https://doi.org/10.1093/nar/gkz524

Environmental pH and peptide signaling control virulence of Streptococcus pyogenes via a quorum-sensing pathway
Do, H, Makthal, N, VanderWal, AR, Saavedra, MO, Olsen, RJ, Musser, JM & Kumaraswami, M 2019, Nature Communications, vol. 10, no. 1, 2586. https://doi.org/10.1038/s41467-019-10556-8

Integrated analysis of population genomics, transcriptomics and virulence provides novel insights into Streptococcus pyogenes pathogenesis
Kachroo, P, Eraso, JM, Beres, SB, Olsen, RJ, Zhu, L, Nasser, W, Bernard, PE, Cantu, CC, Saavedra, MO, Arredondo, MJ, Strope, B, Do, H, Kumaraswami, M, Vuopio, J, Gröndahl-Yli-Hannuksela, K, Kristinsson, KG, Gottfredsson, M, Pesonen, M, Pensar, J, Davenport, ER, Clark, AG, Corander, J, Caugant, DA, Gaini, S, Magnussen, MD, Kubiak, SL, Nguyen, HAT, Long, SW, Porter, AR, DeLeo, FR & Musser, JM 2019, Nature Genetics, vol. 51, no. 3, pp. 548-559. https://doi.org/10.1038/s41588-018-0343-1

Gene fitness landscape of group A streptococcus during necrotizing myositis
Zhu, L, Olsen, RJ, Beres, SB, Eraso, JM, Saavedra, MO, Kubiak, SL, Cantu, CC, Jenkins, L, Charbonneau, ARL, Waller, AS & Musser, JM 2019, The Journal of clinical investigation, vol. 129, no. 2, pp. 887-901. https://doi.org/10.1172/JCI124994

Draft Genome Sequence of Candida auris Strain LOM, a Human Clinical Isolate from Greater Metropolitan Houston, Texas
Long, SW, Olsen, RJ, Nguyen, HAT, Saavedra, MO & Musser, JM 2019, Microbiology Resource Announcements, vol. 8, no. 25, e00532-19. https://doi.org/10.1128/MRA.00532-19

RocA Has Serotype-Specific Gene Regulatory and Pathogenesis Activities in Serotype M28 Group A Streptococcus
Bernard, PE, Kachroo, P, Zhu, L, Beres, SB, Eraso, JM, Kajani, Z, Long, SW, Musser, JM & Olsen, RJ 2018, Infection and immunity, vol. 86, no. 11, e00467-18. https://doi.org/10.1128/IAI.00467-18

Phenotypic variation in the group A Streptococcus due to natural mutation of the accessory protein-encoding gene rocA
Sarkar, P, Danger, JL, Jain, I, Meadows, LA, Beam, C, Medicielo, J, Burgess, C, Musser, JM & Sumby, P 2018, mSphere, vol. 3, no. 5, e00519-18. https://doi.org/10.1128/mSphere.00519-18

Postpartum Group A Streptococcus Case Series: Reach Out to Infection Prevention!
Alexander, AJ, Myers, C, Beres, SB, Olsen, RJ, Musser, JM & Mangino, JE 2018, Open Forum Infectious Diseases, vol. 5, no. 7, pp. ofy159. https://doi.org/10.1093/ofid/ofy159

Signaling by a conserved quorum sensing pathway contributes to growth ex vivo and oropharyngeal colonization of human pathogen group A streptococcus
Makthal, N, Do, H, VanderWal, AR, Olsen, RJ, Musser, JM & Kumaraswami, M 2018, Infection and Immunity, vol. 86, no. 5, e00169-18. https://doi.org/10.1128/IAI.00169-18

Developing an in silico minimum inhibitory concentration panel test for Klebsiella pneumonia
Nguyen, M, Brettin, T, Long, SW, Musser, JM, Olsen, RJ, Olson, R, Shukla, M, Stevens, RL, Xia, F, Yoo, H & Davis, JJ 2018, Scientific Reports, vol. 8, no. 1, 421. https://doi.org/10.1038/s41598-017-18972-w

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