Musser lab Publications


Phenotypic Variation in the Group A Streptococcus Due to Natural Mutation of the Accessory Protein-Encoding Gene rocA
Sarkar, P, Danger, JL, Jain, I, Meadows, LA, Beam, C, Medicielo, J, Burgess, C, Musser, JM & Sumby, P 2018, mSphere, vol. 3, no. 5. DOI: 10.1128/mSphere.00519-18

Postpartum Group A Streptococcus Case Series: Reach Out to Infection Prevention!
Alexander, AJ, Myers, C, Beres, SB, Olsen, RJ, Musser, JM & Mangino, JE 2018, Open Forum Infectious Diseases, vol. 5, no. 7, pp. ofy159. DOI: 10.1093/ofid/ofy159

Signaling by a conserved quorum sensing pathway contributes to growth ex vivo and oropharyngeal colonization of human pathogen group A streptococcus
Makthal, N, Do, H, VanderWal, AR, Olsen, RJ, Musser, JM & Kumaraswami, M 2018, Infection and Immunity, vol. 86, no. 5, e00169-18. DOI: 10.1128/IAI.00169-18

Genome sequence analysis of emm89 Streptococcus pyogenes strains causing infections in Scotland, 2010–2016
Beres, SB, Olsen, RJ, Saavedra, MO, Ure, R, Reynolds, A, Lindsay, DSJ, Smith, AJ & Musser, JM 2017, Journal of Medical Microbiology, vol. 66, no. 12, 000622, pp. 1765-1773. DOI: 10.1099/jmm.0.000622

Developing an in silico minimum inhibitory concentration panel test for Klebsiella pneumonia
Nguyen, M, Brettin, T, Long, SW, Musser, JM, Olsen, RJ, Olson, R, Shukla, M, Stevens, RL, Xia, F, Yoo, H & Davis, JJ 2018, Scientific Reports, vol. 8, no. 1, 421. DOI: 10.1038/s41598-017-18972-w


Novel genes required for the fitness of Streptococcus pyogenes in human saliva
Zhu, L, Charbonneau, ARL, Waller, AS, Olsen, RJ, Beres, SB & Musser, JM 2017, mSphere, vol. 2, no. 6, e00460-17. DOI: 10.1128/mSphereDirect.00460-17

Leaderless secreted peptide signaling molecule alters global gene expression and increases virulence of a human bacterial pathogen
Do, H, Makthal, N, VanderWal, AR, Rettel, M, Savitski, MM, Peschek, N, Papenfort, K, Olsen, RJ, Musser, JM & Kumaraswami, M 2017, Proceedings of the National Academy of Sciences. DOI: 10.1073/pnas.1705972114

Increased pilus production conferred by a naturally occurring mutation alters hostpathogen interaction in favor of carriage in Streptococcus pyogenes
Flores, AR, Olsen, RJ, Cantu, C, Pallister, KB, Guerra, FE, Voyich, JM & Musser, JM 2017, Infection and Immunity, vol. 85, no. 5, e00949-16. DOI: 10.1128/IAI.00949-16

Rapid emergence of a new clone impacts the population at risk and increases the incidence of type emm89 group A Streptococcus invasive disease
Teatero, S, Coleman, BL, Beres, SB, Olsen, RJ, Kandel, C, Reynolds, O, Athey, TBT, Musser, JM, McGeer, A & Fittipaldi, N 2017, Open Forum Infectious Diseases, vol. 4, no. 2, ofx042. DOI: 10.1093/ofid/ofx042


Interacting networks of resistance, virulence and core machinery genes identified by genome-wide epistasis analysis
Skwark, MJ, Croucher, NJ, Puranen, S, Chewapreecha, C, Pesonen, M, Xu, YY, Turner, P, Harris, SR, Beres, SB, Musser, JM, Parkhill, J, Bentley, SD, Aurell, E & Corander, J 2017, PLoS Genetics, vol. 13, no. 2, pp. e1006508. DOI: 10.1371/journal.pgen.1006508

Population genomic analysis of 1,777 extended-spectrum beta-lactamase-producing Klebsiella pneumoniae isolates, Houston, Texas: Unexpected abundance of clonal group 307
Long, SW, Olsen, RJ, Eagar, TN, Beres, SB, Zhao, P, Davis, JJ, Brettin, T, Xia, F & Musser, JM 2017, mBio, vol. 8, no. 3, e00489-17. DOI: 10.1128/mBio.00489-17

Contribution of Secreted NADase and Streptolysin O to the Pathogenesis of Epidemic Serotype M1 Streptococcus pyogenes Infections
Zhu, L, Olsen, RJ, Lee, JD, Porter, AR, DeLeo, FR & Musser, JM 2017, American Journal of Pathology. DOI: 10.1016/j.ajpath.2016.11.003

Deletion of atoR from Streptococcus pyogenes Results in hypervirulence in a mouse model of sepsis and is LuxS independent
Sitkiewicz, I & Musser, JM 2017, Polish Journal of Microbiology, vol. 66, no. 1, pp. 17-24. DOI: 10.5604/17331331.1234989

Genomic Characteristics Behind the Spread of Bacteremic Group A Streptococcus Type emm89 in Finland, 2004-2014
Latronico, F, Nasser, W, Puhakainen, K, Ollgren, J, Hyyryläinen, H-L, Beres, SB, Lyytikäinen, O, Jalava, J, Musser, JM & Vuopio, J 2016, Journal of Infectious Diseases, vol. 214, no. 12, pp. 1987-1995. DOI: 10.1093/infdis/jiw468

Genomic Landscape of Intrahost Variation in Group A Streptococcus: Repeated and Abundant Mutational Inactivation of the fabT Gene Encoding a Regulator of Fatty Acid Synthesis
Eraso, JM, Olsen, RJ, Beres, SB, Kachroo, P, Porter, AR, Nasser, W, Bernard, PE, DeLeo, FR & Musser, JM 2016, Infection and Immunity, vol. 84, no. 12, pp. 3268-3281. DOI: 10.1128/IAI.00608-16

Unique footprint in the scl1.3 locus affects adhesion and biofilm formation of the invasive M3-Type Group A Streptococcus
Bachert, BA, Choi, SJ, LaSala, PR, Harper, TI, McNitt, DH, Boehm, DT, Caswell, CC, Ciborowski, P, Keene, DR, Flores, AR, Musser, JM, Squeglia, F, Marasco, D, Berisio, R & Lukomski, S 2016, Frontiers in Cellular and Infection Microbiology, vol. 6, no. AUG, 90. DOI: 10.3389/fcimb.2016.00090

Intergenic variable-number tandem-repeat polymorphism upstream of rocA alters toxin production and enhances virulence in Streptococcus pyogenes
Zhu, L, Olsen, RJ, Horstmann, N, Shelburne, SA, Fan, J, Hu, T & Musser, JM 2016, Infection and Immunity, vol. 84, no. 7, pp. 2086-2093. DOI: 10.1128/IAI.00258-16

Integrating rapid diagnostics and antimicrobial stewardship in two community hospitals improved process measures and antibiotic adjustment time
Lockwood, AM, Perez, KK, Musick, WL, Ikwuagwu, JO, Attia, E, Fasoranti, OO, Cernoch, PL, Olsen, RJ & Musser, JM 2016, Infection Control and Hospital Epidemiology, vol. 37, no. 4, pp. 425-432. DOI: 10.1017/ice.2015.313