Mitra lab Publications


Ligand-induced gene activation is associated with oxidative genome damage whose repair is required for transcription
Sengupta, S, Wang, H, Yang, C, Szczesny, B, Hegde, ML & Mitra, S 2020, , Proceedings of the National Academy of Sciences of the United States of America, vol. 117, no. 36, pp. 22183-22192. https://doi.org/10.1073/pnas.1919445117


Gold Nanoparticles Radio-Sensitize and Reduce Cell Survival in Lewis Lung Carcinoma
Pandey, A, Vighetto, V, Di Marzio, N, Ferraro, F, Hirsch, M, Ferrante, N, Mitra, S, Grattoni, A & Filgueira, CS 2020, , Nanomaterials, vol. 10, no. 9. https://doi.org/10.3390/nano10091717

Pervasive Genomic Damage in Experimental Intracerebral Hemorrhage: Therapeutic Potential of a Mechanistic-Based Carbon Nanoparticle
Dharmalingam, P, Talakatta, G, Mitra, J, Wang, H, Derry, PJ, Nilewski, LG, McHugh, EA, Fabian, RH, Mendoza, K, Vasquez, V, Hegde, PM, Kakadiaris, E, Roy, T, Boldogh, I, Hegde, VL, Mitra, S, Tour, JM, Kent, TA & Hegde, M 2020, , ACS Nano, vol. 14, no. 3, pp. 2827-2846. https://doi.org/10.1021/acsnano.9b05821

Motor neuron disease-associated loss of nuclear TDP-43 is linked to DNA double-strand break repair defects
Mitra, J, Guerrero, EN, Hegde, PM, Liachko, NF, Wang, H, Vasquez, V, Gao, J, Pandey, A, Paul Taylor, J, Kraemer, BC, Wu, P, Boldogh, I, Garruto, RM, Mitra, S, Rao, KS & Hegde, M 2019, , Proceedings of the National Academy of Sciences of the United States of America, vol. 116, no. 10, pp. 4696-4705. https://doi.org/10.1073/pnas.1818415116

Mutant FUS causes DNA ligation defects to inhibit oxidative damage repair in Amyotrophic Lateral Sclerosis
Wang, H, Guo, W, Mitra, J, Hegde, PM, Vandoorne, T, Eckelmann, BJ, Mitra, S, Tomkinson, AE, Van Den Bosch, L & Hegde, ML 2018, , Nature Communications, vol. 9, no. 1, 3683. https://doi.org/10.1038/s41467-018-06111-6


SMAD4 gene mutation renders pancreatic cancer resistance to radiotherapy through promotion of autophagy
Wang, F, Xia, X, Yang, C, Shen, J, Mai, J, Kim, HC, Kirui, D, Kang, Y, Fleming, JB, Koay, EJ, Mitra, S, Ferrari, M & Shen, H 2018, , Clinical Cancer Research, vol. 24, no. 13, pp. 3176-3185. https://doi.org/10.1158/1078-0432.CCR-17-3435

Differentially localized survivin and STAT3 as markers of gastric cancer progression: Association with Helicobacter pylori
Pandey, A, Tripathi, SC, Shukla, S, Mahata, S, Vishnoi, K, Misra, SP, Misra, V, Mitra, S, Dwivedi, M & Bharti, AC 2018, Cancer Reports, vol. 1, no. 1, e1004. https://doi.org/10.1002/cnr2.1004

Chromatin-Bound Oxidized a-Synuclein Causes Strand Breaks in Neuronal Genomes in in vitro Models of Parkinson's Disease
Vasquez, V, Mitra, J, Hegde, PM, Pandey, A, Sengupta, S, Mitra, S, Rao, SK & Hegde, ML 2017, , Journal of Alzheimers Disease, vol. 60, no. s1, pp. S133-S150. https://doi.org/10.3233/JAD-170342


Aurora kinase B dependent phosphorylation of 53BP1 is required for resolving merotelic kinetochore-microtubule attachment errors during mitosis
Wang, H, Peng, B, Pandita, RK, Engler, DA, Matsunami, RK, Xu, X, Hegde, PM, Butler, EB, Pandita, TK, Mitra, S, Xu, B & Hegde, ML 2017, , Oncotarget, vol. 8, no. 30, pp. 48671-48687. https://doi.org/10.18632/oncotarget.16225

DNA damage responses in central nervous system and age-associated neurodegeneration
Hegde, ML, Bohr, VA & Mitra, S 2017, , Mechanisms of Ageing and Development, vol. 161, pp. 1-3. https://doi.org/10.1016/j.mad.2017.01.010

Microhomology-mediated end joining is activated in irradiated human cells due to phosphorylation-dependent formation of the XRCC1 repair complex
Dutta, A, Eckelmann, B, Adhikari, S, Ahmed, KM, Sengupta, S, Pandey, A, Hegde, PM, Tsai, M-S, Tainer, JA, Weinfeld, M, Hegde, ML & Mitra, S 2016, , Nucleic Acids Research, vol. 45, no. 5, pp. 2585-2599. https://doi.org/10.1093/nar/gkw1262

Regulation of oxidized base damage repair by chromatin assembly factor 1 subunit A
Yang, C, Sengupta, S, Hegde, PM, Mitra, J, Jiang, S, Holey, B, Sarker, AH, Tsai, M-S, Hegde, ML & Mitra, S 2016, , Nucleic Acids Research, vol. 45, no. 2, pp. 739-748. https://doi.org/10.1093/nar/gkw1024

Depletion of tyrosyl DNA phosphodiesterase 2 activity enhances etoposide-mediated double-strand break formation and cell killing
Kont, YS, Dutta, A, Mallisetty, A, Mathew, J, Minas, T, Kraus, C, Dhopeshwarkar, P, Kallakury, B, Mitra, S, Üren, A & Adhikari, S 2016, , DNA Repair, vol. 43, pp. 38-47. https://doi.org/10.1016/j.dnarep.2016.04.009

Scaffold attachment factor A (SAF-A) and Ku temporally regulate repair of radiation-induced clustered genome lesions
Hegde, ML, Dutta, A, Yang, C, Mantha, AK, Hegde, PM, Pandey, A, Sengupta, S, Yu, Y, Calsou, P, Chen, D, Lees-Miller, SP & Mitra, S 2016, , Oncotarget. https://doi.org/10.18632/oncotarget.9914


8-Oxoguanine DNA glycosylase1-driven DNA repair-A paradoxical role in lung aging
German, P, Saenz, D, Szaniszlo, P, Aguilera-Aguirre, L, Pan, L, Hegde, ML, Bacsi, A, Hajas, G, Radak, Z, Ba, X, Mitra, S, Papaconstantinou, J & Boldogh, I 2016, , Mechanisms of Ageing and Development, vol. 161, pp. 51-65. https://doi.org/10.1016/j.mad.2016.06.009

Increased human AP endonuclease 1 level confers protection against the paternal age effect in mice
Sanchez, JR, Reddick, TL, Perez, M, Centonze, VE, Mitra, S, Izumi, T, McMahan, CA & Walter, CA 2015, , Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis, vol. 779, pp. 124-133. https://doi.org/10.1016/j.mrfmmm.2015.06.008