Li lab Publications


Targeted Maytansinoid Conjugate Improves Therapeutic Index for Metastatic Breast Cancer Cells
Jiang, Z, Yang, Z, Li, F, Li, Z, Fishkin, N & Burgess, K 2018, Bioconjugate Chemistry, vol. 29, no. 9, pp. 2920-2926. DOI: 10.1021/acs.bioconjchem.8b00340

A zwitterionic near-infrared dye linked TrkC targeting agent for imaging metastatic breast cancer
Yang, Z, Usama, SM, Li, F, Burgess, K & Li, Z 2018, MedChemComm, vol. 9, no. 10, pp. 1754-1760. DOI: 10.1039/c8md00190a

A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
Wolfram, J, Nizzero, S, Liu, H, Li, F, Zhang, G, Li, Z, Shen, H, Blanco, E & Ferrari, M 2017, Scientific Reports, vol. 7, no. 1, pp. 13738. DOI: 10.1038/s41598-017-14221-2

The Isomeric Preference of an Atypical Dopamine Transporter Inhibitor Contributes to Its Selection of the Transporter Conformation
Abramyan, AM, Stolzenberg, S, Li, Z, Loland, CJ, Noé, F & Shi, L 2017, ACS Chemical Neuroscience, vol. 8, no. 8, pp. 1735-1746. DOI: 10.1021/acschemneuro.7b00094

The role of transmembrane segment 5 (TM5) in Na2 release and the conformational transition of neurotransmitter: sodium symporters toward the inward-open state
Stolzenberg, S, Li, Z, Quick, M, Malinauskaite, L, Nissen, P, Weinstein, H, Javitch, JA & Shi, L 2017, Journal of Biological Chemistry, vol. 292, no. 18, pp. 7372-7384. DOI: 10.1074/jbc.M116.757153

Pet Imaging and its Application in Cardiovascular Diseases
Li, Z, Gupte, AA, Zhang, A & Hamilton, DJ 2017, Methodist DeBakey Cardiovascular Journal, vol. 13, no. 1, pp. 29-33. DOI: 10.14797/mdcj-13-1-29

An agent for optical imaging of TrkC-expressing, breast cancer
Kamkaew, A, Li, F, Li, Z & Burgess, K 2017, MedChemComm, vol. 8, no. 10, pp. 1946-1952. DOI: 10.1039/c7md00328e

Prediction and Early Evaluation of Anticancer Therapy Response: From Imaging of Drug Efflux Pumps to Targeted Therapy Response
Menga, Q, Li, Z & Li, S 2016, Current Medicinal Chemistry, vol. 23, no. 41, pp. 4625-4638. DOI: 10.2174

Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Bai, J, Liao, C, Liu, Y, Qin, X, Chen, J, Qiu, Y, Qin, D, Li, Z, Tu, ZC & Jiang, S 2016, Journal of Medicinal Chemistry, vol. 59, no. 12, pp. 5766-5779. DOI: 10.1021/acs.jmedchem.6b00324

Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter: Sodium symporter
Billesbølle, CB, Krüger, MB, Shi, L, Quick, M, Li, Z, Stolzenberg, S, Kniazeff, J, Gotfryd, K, Mortensen, JS, Javitch, JA, Weinstein, H, Loland, CJ & Gether, U 2015, Journal of Biological Chemistry, vol. 290, no. 44, pp. 26725-26738. DOI: 10.1074/jbc.M115.677658

Discovery of Novel Class i Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Yao, Y, Tu, Z, Liao, C, Wang, Z, Li, S, Yao, H, Li, Z & Jiang, S 2015, Journal of Medicinal Chemistry, vol. 58, no. 19, pp. 7672-7680. DOI: 10.1021/acs.jmedchem.5b01044


An HDAC-Targeted Imaging Probe LBH589-Cy5.5 for Tumor Detection and Therapy Evaluation
Meng, Q, Liu, Z, Li, F, Ma, J, Wang, H, Huan, Y & Li, Z 2015, Molecular Pharmaceutics, vol. 12, no. 7, pp. 2469-2476. DOI: 10.1021/acs.molpharmaceut.5b00167

Identification of a second substrate-binding site in solute-sodium symporters
Li, Z, Lee, ASE, Bracher, S, Jung, H, Paz, A, Kumar, JP, Abramson, J, Quick, M & Shi, L 2015, Journal of Biological Chemistry, vol. 290, no. 12. DOI: 10.1074/jbc.A114.584383

One-step 18F labeling of non-peptidic bivalent integrin avß3 antagonist for cancer imaging
Wang, W, Liu, Z & Li, Z 2015, Bioconjugate Chemistry, vol. 26, no. 1, pp. 24-28. DOI: 10.1021/bc500590f

Identification of a second substrate-binding Site in solute-sodium symporters
Li, Z, Lee, ASE, Bracher, S, Jung, H, Paz, A, Kumar, JP, Abramson, J, Quick, M & Shi, L 2015, Journal of Biological Chemistry, vol. 290, no. 1, pp. 127-141. DOI: 10.1074/jbc.M114.584383

An HDAC-Targeted Near-Infrared Probe LBH589-Cy5.5 for Tumor Detection and Therapy Evaluation
Li, Z 2015, Molecular Pharmacology, vol. 12, no. 7, pp. 2469-76.

Long-term benefit of male circumcision to the reduction of urinary tract infections and genitourinary cancers in China
Zhao, FJ, Li, PS, Lü, NQ, Lee, R, Peng, YF, Cheng, F, Li, Z, Xu, HQ, Barone, M, Goldstein, M & Xia, SJ 2014, Zhonghua nan ke xue = National journal of andrology, vol. 20, no. 11, pp. 969-977.

Design, synthesis, and biological evaluation of 1, 3-disubstituted-pyrazole derivatives as new class I and IIb histone deacetylase inhibitors
Yao, Y, Liao, C, Li, Z, Wang, Z, Sun, Q, Liu, C, Yang, Y, Tu, Z & Jiang, S 2014, European Journal of Medicinal Chemistry, vol. 86, pp. 639-652. DOI: 10.1016/j.ejmech.2014.09.024

Specific and sensitive tumor imaging using biostable oligonucleotide aptamer probes
Zeng, Z, Parekh, P, Li, Z, Shi, Z-Z, Tung, C-H & Zu, Y 2014, Theranostics, vol. 4, no. 9, pp. 945-52. DOI: 10.7150/thno.9246