Li lab Publications


Single-Molecule Force Measurement Guides the Design of Multivalent Ligands with Picomolar Affinity
Yang, Z, Jiang, S, Li, F, Qiu, Y, Gu, J, Pettigrew, RI, Ferrari, M, Hamilton, DJ & Li, Z 2019, Angewandte Chemie - International Edition. https://doi.org/10.1002/anie.201814347

Targeted Maytansinoid Conjugate Improves Therapeutic Index for Metastatic Breast Cancer Cells
Jiang, Z, Yang, Z, Li, F, Li, Z, Fishkin, N & Burgess, K 2018, Bioconjugate Chemistry, vol. 29, no. 9, pp. 2920-2926. https://doi.org/10.1021/acs.bioconjchem.8b00340

MULTIVALENT LIGANDS TARGETING VEGFR
Li, Z & Li, F 2018, , Patent No. US 10 , 011 , 587 B2.

Developing VEGF receptors targeted molecular probes for PET imaging of vulnerable atherosclerotic plaques
Yang, Z, Li, F & Li, Z 2018, Journal of Nuclear Medicine, vol. 59, no. supplement 1, pp. 1526.

A zwitterionic near-infrared dye linked TrkC targeting agent for imaging metastatic breast cancer
Yang, Z, Usama, SM, Li, F, Burgess, K & Li, Z 2018, MedChemComm, vol. 9, no. 10, pp. 1754-1760. https://doi.org/10.1039/c8md00190a


A chloroquine-induced macrophage-preconditioning strategy for improved nanodelivery
Wolfram, J, Nizzero, S, Liu, H, Li, F, Zhang, G, Li, Z, Shen, H, Blanco, E & Ferrari, M 2017, Scientific Reports, vol. 7, no. 1, pp. 13738. https://doi.org/10.1038/s41598-017-14221-2

The Isomeric Preference of an Atypical Dopamine Transporter Inhibitor Contributes to Its Selection of the Transporter Conformation
Abramyan, AM, Stolzenberg, S, Li, Z, Loland, CJ, Noé, F & Shi, L 2017, ACS Chemical Neuroscience, vol. 8, no. 8, pp. 1735-1746. https://doi.org/10.1021/acschemneuro.7b00094

The role of transmembrane segment 5 (TM5) in Na2 release and the conformational transition of neurotransmitter: sodium symporters toward the inward-open state
Stolzenberg, S, Li, Z, Quick, M, Malinauskaite, L, Nissen, P, Weinstein, H, Javitch, JA & Shi, L 2017, Journal of Biological Chemistry, vol. 292, no. 18, pp. 7372-7384. https://doi.org/10.1074/jbc.M116.757153

Pet Imaging and its Application in Cardiovascular Diseases
Li, Z, Gupte, AA, Zhang, A & Hamilton, DJ 2017, Methodist DeBakey Cardiovascular Journal, vol. 13, no. 1, pp. 29-33. https://doi.org/10.14797/mdcj-13-1-29

An agent for optical imaging of TrkC-expressing, breast cancer
Kamkaew, A, Li, F, Li, Z & Burgess, K 2017, MedChemComm, vol. 8, no. 10, pp. 1946-1952. https://doi.org/10.1039/c7md00328e


Structure-Based Design of Potent Nicotinamide Phosphoribosyltransferase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Bai, J, Liao, C, Liu, Y, Qin, X, Chen, J, Qiu, Y, Qin, D, Li, Z, Tu, ZC & Jiang, S 2016, Journal of Medicinal Chemistry, vol. 59, no. 12, pp. 5766-5779. https://doi.org/10.1021/acs.jmedchem.6b00324

Substrate-induced unlocking of the inner gate determines the catalytic efficiency of a neurotransmitter: Sodium symporter
Billesbølle, CB, Krüger, MB, Shi, L, Quick, M, Li, Z, Stolzenberg, S, Kniazeff, J, Gotfryd, K, Mortensen, JS, Javitch, JA, Weinstein, H, Loland, CJ & Gether, U 2015, Journal of Biological Chemistry, vol. 290, no. 44, pp. 26725-26738. https://doi.org/10.1074/jbc.M115.677658

Discovery of Novel Class i Histone Deacetylase Inhibitors with Promising in Vitro and in Vivo Antitumor Activities
Yao, Y, Tu, Z, Liao, C, Wang, Z, Li, S, Yao, H, Li, Z & Jiang, S 2015, Journal of Medicinal Chemistry, vol. 58, no. 19, pp. 7672-7680. https://doi.org/10.1021/acs.jmedchem.5b01044


An HDAC-Targeted Imaging Probe LBH589-Cy5.5 for Tumor Detection and Therapy Evaluation
Meng, Q, Liu, Z, Li, F, Ma, J, Wang, H, Huan, Y & Li, Z 2015, Molecular Pharmaceutics, vol. 12, no. 7, pp. 2469-2476. https://doi.org/10.1021/acs.molpharmaceut.5b00167

Identification of a second substrate-binding site in solute-sodium symporters
Li, Z, Lee, ASE, Bracher, S, Jung, H, Paz, A, Kumar, JP, Abramson, J, Quick, M & Shi, L 2015, Journal of Biological Chemistry, vol. 290, no. 12. https://doi.org/10.1074/jbc.A114.584383


Identification of a second substrate-binding Site in solute-sodium symporters
Li, Z, Lee, ASE, Bracher, S, Jung, H, Paz, A, Kumar, JP, Abramson, J, Quick, M & Shi, L 2015, Journal of Biological Chemistry, vol. 290, no. 1, pp. 127-141. https://doi.org/10.1074/jbc.M114.584383