Publications


Dysfunction of iPSC-derived endothelial cells in human Hutchinson–Gilford progeria syndrome
Matrone, G, Amirthalingam Thandavarayan, R, Walther, BK, Meng, S, Mojiri, A & Cooke, JP 2019, Cell Cycle, vol. 18, no. 19, pp. 2495-2508. https://doi.org/10.1080/15384101.2019.1651587

Transient introduction of human telomerase mRNA improves hallmarks of progeria cells
Li, Y, Zhou, G, Bruno, IG, Zhang, N, Sho, S, Tedone, E, Lai, TP, Cooke, JP & Shay, JW 2019, Aging Cell, vol. 18, no. 4, e12979. https://doi.org/10.1111/acel.12979

Endothelial senescence is induced by phosphorylation and nuclear export of telomeric repeat binding factor 2–interacting protein
Kotla, S, Vu, HT, Ko, KA, Wang, Y, Imanishi, M, Heo, K-S, Fujii, Y, Thomas, TN, Gi, YJ, Mazhar, H, Paez-Mayorga, J, Shin, J-H, Tao, Y, Giancursio, CJ, Medina, JLM, Taunton, J, Lusis, AJ, Cooke, JP, Fujiwara, K, Le, N-T & Abe, J 2019, JCI Insight, vol. 4, no. 9, e124867. https://doi.org/10.1172/jci.insight.124867

Inflammation and Its Role in Regeneration and Repair
Cooke, JP 2019, Circulation Research, vol. 124, no. 8, pp. 1166-1168. https://doi.org/10.1161/CIRCRESAHA.118.314669

MAGI1 as a link between endothelial activation and ER stress drives atherosclerosis
Abe, J-I, Ko, KA, Kotla, S, Wang, Y, Paez-Mayorga, J, Shin, IJ, Imanishi, M, Vu, HT, Tao, Y, Leiva-Juarez, MM, Thomas, TN, Medina, JL, Won, JH, Fujii, Y, Giancursio, CJ, McBeath, E, Shin, J-H, Guzman, L, Abe, RJ, Taunton, J, Mochizuki, N, Faubion, W, Cooke, JP, Fujiwara, K, Evans, SE & Le, N-T 2019, JCI Insight, vol. 4, no. 7. https://doi.org/10.1172/jci.insight.125570

AIBP-mediated cholesterol efflux instructs hematopoietic stem and progenitor cell fate
Gu, Q, Yang, X, Lv, J, Zhang, J, Xia, B, Kim, JD, Wang, R, Xiong, F, Meng, S, Clements, TP, Tandon, B, Wagner, DS, Diaz, MF, Wenzel, PL, Miller, YI, Traver, D, Cooke, JP, Li, W, Zon, LI, Chen, K, Bai, Y & Fang, L 2019, Science, pp. eaav1749. https://doi.org/10.1126/science.aav1749

Convergences of Life Sciences and Engineering in Understanding and Treating Heart Failure
Berry, JL, Zhu, W, Tang, YL, Krishnamurthy, P, Ge, Y, Cooke, JP, Chen, Y, Garry, DJ, Yang, HT, Rajasekaran, NS, Koch, WJ, Li, S, Domae, K, Qin, G, Cheng, K, Kamp, TJ, Ye, L, Hu, S, Ogle, BM, Rogers, JM, Abel, ED, Davis, ME, Prabhu, SD, Liao, R, Pu, WT, Wang, Y, Ping, P, Bursac, N, Vunjak-Novakovic, G, Wu, JC, Bolli, R, Menasché, P & Zhang, J 2019, Circulation Research, vol. 124, no. 1, pp. 161-169. https://doi.org/10.1161/CIRCRESAHA.118.314216

Asymmetric dimethylarginine predicts impaired epicardial coronary vasomotion in patients with angina in the absence of obstructive coronary artery disease
Parikh, RV, Pargaonkar, V, Ball, RL, Kobayashi, Y, Kimura, T, Yeung, AC, Cooke, JP & Tremmel, JA 2019, International Journal of Cardiology. https://doi.org/10.1016/j.ijcard.2019.07.062


TBX20 Regulates Angiogenesis Through the Prokineticin 2-Prokineticin Receptor 1 Pathway
Meng, S, Gu, Q, Yang, X, Lv, J, Owusu, I, Matrone, G, Chen, K, Cooke, JP & Fang, L 2018, Circulation, vol. 138, no. 9, pp. 913-928. https://doi.org/10.1161/CIRCULATIONAHA.118.033939

Novel Markers for Adverse Events in Atrial Fibrillation
Cooke, JP & Sukhovershin, R 2018, Journal of the American College of Cardiology, vol. 72, no. 7, pp. 734-737. https://doi.org/10.1016/j.jacc.2018.04.091

Cardiomyocyte Maturation Requires TLR3 Activated Nuclear Factor Kappa B
Hodgkinson, CP, Pratt, RE, Kirste, I, Dal-Pra, S, Cooke, JP & Dzau, VJ 2018, Stem Cells, vol. 36, no. 8, pp. 1198-1209. https://doi.org/10.1002/stem.2833

Induced pluripotent stem cell-derived endothelial cells promote angiogenesis and accelerate wound closure in a murine excisional wound healing model
Clayton, ZE, Tan, RP, Miravet, MM, Lennartsson, K, Cooke, JP, Bursill, CA, Wise, SG & Patel, S 2018, Bioscience Reports, vol. 38, no. 4, BSR20180563. https://doi.org/10.1042/BSR20180563

Transflammation: How Innate Immune Activation and Free Radicals Drive Nuclear Reprogramming
Meng, S, Chanda, P, Thandavarayan, RA & Cooke, JP 2018, Antioxidants and Redox Signaling, vol. 29, no. 2, pp. 205-218. https://doi.org/10.1089/ars.2017.7364


Interdisciplinary Models for Research and Clinical Endeavors in Genomic Medicine: A Scientific Statement From the American Heart Association
American Heart Association Council on Genomic and Precision Medicine; Council on Cardiovascular Disease in the Young; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; Council on Peripheral Vascular Disease; Council on Quality of Care and Outcomes Research; and Stroke Council 2018, Circulation. Genomic and precision medicine, vol. 11, no. 6, pp. e000046. https://doi.org/10.1161/HCG.0000000000000046

Inflammation-targeted vascular nanomedicine
Cooke, JP & Ferrari, M 2018, Nature Biomedical Engineering, vol. 2, no. 5, pp. 269-270. https://doi.org/10.1038/s41551-018-0241-y

Harnessing and Optimizing the Interplay between Immunotherapy and Radiotherapy to Improve Survival Outcomes
Mujoo, K, Hunt, CR, Pandita, RK, Ferrari, M, Krishnan, S, Cooke, JP, Hahn, S & Pandita, TK 2018, Molecular Cancer Research, vol. 16, no. 8, pp. 1209-1214. https://doi.org/10.1158/1541-7786.MCR-17-0743

Integration of induced pluripotent stem cell-derived endothelial cells with polycaprolactone/gelatin-based electrospun scaffolds for enhanced therapeutic angiogenesis
Tan, RP, Chan, AHP, Lennartsson, K, Miravet, MM, Lee, BSL, Rnjak-Kovacina, J, Clayton, ZE, Cooke, JP, Ng, MKC, Patel, S & Wise, SG 2018, Stem Cell Research and Therapy, vol. 9, no. 1, 70. https://doi.org/10.1186/s13287-018-0824-2

Biomimetic nanoparticles with enhanced affinity towards activated endothelium as versatile tools for theranostic drug delivery
Martinez, JO, Molinaro, R, Hartman, KA, Boada, C, Sukhovershin, R, De Rosa, E, Kirui, D, Zhang, S, Evangelopoulos, M, Carter, AM, Bibb, JA, Cooke, JP & Tasciotti, E 2018, Theranostics, vol. 8, no. 4, pp. 1131-1145. https://doi.org/10.7150/thno.22078

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