Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Tommaso Novellino

Tommaso Novellino, M.S.

Tommaso Novellino, M.S.

Tommaso Novellino, M.S.

Research Fellow
Houston Methodist Research Institute

E-mail: tnovellino@houstonmethodist.org
Phone: 713-441-7450
Fax: 713-790-3033


Education

B.S.   Biomedical Engineering, Biomedical Campus University of Rome, Italy
M.S.   Biomedical Engineering, Biomedical Campus University of Rome, Italy
Ph.D.   Biomedical Engineering, Biomedical Campus University of Rome, Italy
 

 

Biography

Tommaso Novellino is currently a research fellow at Houston Methodist Research Institute. His PhD topics included the study of cellular mechanics and characterization using atomic force microscopy (AFM) and confocal microscopy. He also has expertise in simulation of deep brain stimulation (DBS)nanochannelled delivery system (nDS). He is expected to graduate in March 2011.

Description of Research

  • Dynamical in vitro characterization of tumoral cells onto endothelial cells modeling circulating tumor cells by flow chamber system
  • Quasi-statical in vitro characterization of endothelial cells mechanics upon internalized gold nanoparticles concentration-dependent stimulation by atomic force and confocal microscopy
  • Quasi-statical in vitro characterization of endothelial cells mechanics upon pro-inflammatory cytokine tumor necrosis factor alpha stimulation by atomic force and confocal microscopy
  • Dynamical in vivo/in vitro characterization of anti-tumoral/viral drug human interferon alpha long-term release through a nanochanneled delivery system

Major Areas of Research

Biomedical engineering, nanomedicine, drug-delivery, biomechanics.

Recent Publications

Lee SY, Zaske AM, Novellino T, Danila D, Ferrari M, Conyers J, Decuzzi P. Probing the mechanical properties of TNF-a stimulated endothelial cell with atomic force microscopy. Int J Nanomedicine. 2011;6: 179–195.

Liberti M, Apollonio F, Paffi A, Parazzini M, Maggio F, Novellino T, Ravazzani P, D’Inzeo G. Fundamental electrical quantities in deep brain stimulation: influence of domain dimensions and boundary conditions. Conf Proc IEEE Eng Med Biol Soc 2007. 2007;6669–6672. PMID: 18003555.