Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine


Xiaofeng Xia, Ph.D.


Xiaofeng Xia, Ph.D.

Xiaofeng Xia, Ph.D.

Assistant Member 
Houston Methodist Research Institute
Director, NeuroDrug Discovery Program
TT and WF Chao Center for BRAIN
Department of Systems Medicine and Bioengineering
Assistant Professor
Weill Cornell Medical College of Cornell University

Phone: 713-441-7261
E-mail: xxia@houstonmethodist.org


B.S.   Tsinghua University, Beijing, P.R.China (Biology)
Ph.D.   Tsinghua University, Beijing, P.R.China (Biophysics)

Postdoctoral Training

Postdoctoral Fellowship, University of Wisconsin, Madison, WI (Molecular/Cellular Biology)



Dr. Xia received his Ph.D. at Tsinghua University, in China in 2002. From 2002 to 2006, he completed a postdoctoral fellowship at the University of Wisconsin in Madison. After that, he joined the WiCell Research Institute and worked as an assistant scientist until joining Houston Methodist Research Institute in 2007. He has worked in a number of areas including bioinformatics, neurotransmitter releasing, and neuronal differentiation of stem cells. He is currently collaborating with other investigators on high content drug screening on neural stem cells.

Description of Research

Dr. Xia’s research focuses on developing novel high-content screening techniques on neurodegeneration and neuroregeneration research.

Major Areas of Research

neural stem cells, high-content screening, bioinformatics

Recent Publications

Xia X, Ayala M, Thiede BR, Zhang SC (2008) In vitro and in vivo induced transgene expression in human embryonic stem cells and derivatives. Stem Cells 26:525-533.

Xia X, Zhang Y, Zieth C, Zhang SC (2007) Transgenes delivered by lentiviral vector are suppressed in human embryonic stem cells in a promoter-dependent manner. Stem Cells Dev. 16:167-176.

Xia X, Zhang SC (2007) Genetic modification of human embryonic stem cells. Biotechnology & Genetic Engineering Reviews, Vol. 24, Nottingham University Press.

Xia X, Zhang SC (2007) Neural precursor differentiation from human embryonic stem cells. Methods in Molecular Medicine, Humana Press (invited chapter, in press)

Aikawa Y, Xia X, Martin TF (2006) SNAP25, but not syntaxin 1A, recycles via an ARF6-regulated pathway in neuroendocrine cells. Mol Biol Cell 17:711-722.