Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Investigators

Miguel Quinones, M.D.

 

Miguel Quinones, MD

Miguel Quinones, M.D.

Senior Member
Methodist Hospital Research Institute

Chair, Department of Cardiology
The Methodist DeBakey Heart & Vascular Center
The Methodist Hospital

Professor of Medicine 
Weill Cornell Medical College of Cornell University

Phone: 713-441-1100
Fax: 713-790-6334

Education

B.S. University of Puerto Rico, San Juan, Peurto Rico
M.D. University of Puerto Rico School of Medicine, San Juan, Peurto Rico

Postdoctoral Training

Internship in Medicine, Columbia University, College of Physicians and Surgeons, New York, NY
Residency, Medicine, Columbia University, College of Physicians and Surgeons, Harlem Hospital, New York, NY
Cardiology Fellowship, Section of Cardiology, Department of Medicine, Baylor College of Medicine, Houston, TX

 

Biography

After serving two years in the military as Chief of Cardiology at Moncrief Army Hospital in Fort Jackson, South Carolina, Dr. Quinones joined the faculty of Baylor College of Medicine in the Department of Medicine in 1977. He was made full professor in 1987 and retained this position until 2005, when he became Chair of the Department of Cardiology at the Methodist Hospital. He served as director of the Echocardiography Laboratory at the Methodist Hospital from 1977 to 2002, and was promoted to medical director of the DeBakey Heart Center in 2003. He is an active member of the American College of Cardiology, the American Heart Association and the American Society of Echocardiography, and currently serves on the Methodist Hospital Physicians Organization Board of Directors and Executive Committee. He has served on the Board of Directors of the American Society of Echocardiography and The American College of Cardiology, and on the editorial board of several peer-reviewed journals including Circulation and the Journal of the American College of Cardiology. Dr. Quinones is an active investigator and has published more than 180 peer-reviewed articles.

Description of Research

Dr. Quinones´s studies cardiac function with a specific focus on using cardiac ultrasound. Early in his career he combined echocardiography with intracardiac pressure measurements to relate myocardial stress to systolic performance. Subsequently, his laboratory made important contributions in developing echocardiographic methods to measure left ventricular volumes and ejection fraction, cardiac output, regurgitant fractions in mitral and aortic insufficiency, and valve area in aortic stenosis. More recently, his laboratory has developed newer methods to evaluate diastolic function and estimate left ventricular filling pressures.

Dr. Quinones played a pivotal role in the development of stress echocardiography as a clinical tool for the evaluation of coronary artery disease. His was the first team to describe the post-treadmill echocardiographic technique that is currently used all over the world. In collaboration with the nuclear cardiology laboratory, they compared exercise echocardiography with SPECT thallium scintigraphy in the same patients. Both techniques were shown to have comparable sensitivity and specificity for detection of coronary artery disease. His laboratory has made important contributions in the field of myocardial perfusion utilizing injections of ultrasonic contrast agents into the aorta or coronary arteries, and is currently investigating the use of new intravenous agents for evaluation of perfusion.

Major Areas of Research

Echocardiography; myocardial perfusion; coronary artery disease

Recent Publications

Park TH, Tayan N, Takeda K, Jeon HK, Quinones MA, Zoghbi WA. (2007) Supine bicycle echocardiography improved diagnostic accuracy and physiologic assessment of coronary artery disease with the incorporation of intermediate stages of exercise. J Am Coll Cardiol 50:1857-63.

Nagueh SF, Buergler JM, Quinones MA, Spencer WH 3rd, Lawrie GM. (2007) Outcome of surgical myectomy after unsuccessful alcohol septal ablation for the treatment of patients with hypertrophic obstructive cardiomyopathy. J Am Coll Cardiol 50:795-8.

Quiñones MA, Zile MR, Massie BM, Kass DA; Writing Committee of the Dartmouth Diastolic Discourses. (2006) Chronic heart failure: a report from the Dartmouth Diastole Discourses. Congest Heart Fail 12:162-5.

Dokainish H, Zoghbi WA, Ambriz E, Lakkis NM, Quinones MA, Nagueh SF. (2006) Comparative cost-effectiveness of B-type natriuretic peptide and echocardiography for predicting outcome in patients with congestive heart failure. J Am Coll Cardiol 97:400-3.

Dokainish H, Zoghbi WA, Lakkis NM, Ambriz E, Patel R, Quinones MA, and Nagueh SF. (2005) Incremental predictive power of B-type natriuretic peptide and tissue Doppler echocardiography in the prognosis of patients with congestive heart failure. J Am Coll Cardiol 45:1223-6.

Frost AE, Quiñones MA, Zoghbi WA, Noon GP. (2005) Reversal of pulmonary hypertension and subsequent repair of atrial septal defect after treatment with continuous intravenous epoprostenol. J Heart Lung Transplant 24:501-3.

Dokainish H, Zoghbi WA, Lakkis NM, Al-Bakshy F, Dhir M, Quinones MA, Nagueh SF. (2004) Optimal noninvasive assessment of left ventricular filling pressures: a comparison of tissue Doppler echocardiography and B-type natriuretic peptide in patients with pulmonary artery catheters. Circulation 109:2432-9.

Dokainish H, Zoghbi WA, Lakkis NM, Quinones MA, Nagueh SF. (2004) Comparative accuracy of B-type natriuretic peptide and tissue Doppler echocardiography in the diagnosis of congestive heart failure. J Am Cardiol 93:1130-5.


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