Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Clinical Trials

Clinical Trials at The Methodist Hospital Research Institute

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Transplant Trials

Active and enrolling clinical trials for Transplant Trials are updated on this page as they become available. You are also welcome to view our clinical trials that are registered with the National Institutes of Health.
 
For more information please contact the study coordinator of the trials listed below or contact the main clinical trials help line 713-441-3250.
 
Graft Failure

LCP-Tacro 3002
Study Status: Active/Enrolling
Investigator: Knight, Richard
Study Coordinator: Brann, Sarah
Phone: 713-441-6394
Summary:This study will evaluate the efficacy and safety of LCP-Tacro (tacrolimus) Tablets administered once-a-day compared to Prograf (tacrolimus) Capsules twice-a-day as immunosuppression for the prevention...(read more)
Heart Transplant

CLINICAL TRIALS IN ORGAN TRANSPLANTATION CTOT-11
Study Status: Active/Enrolling
Investigator: Bhimaraj, Arvind
Study Coordinator: Karanja, Eunice
Phone: 713-441-3571
Summary:CTOT-11 STUDY Post heart transplant research study. The study will recruit 400 primary heart transplant recipients from the approximately 25 participating centers. Subjects will be screened, consented...(read more)

Freedom Driver
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purposes of this study are to confirm that the Freedom Driver System is a suitable pneumatic driver for clinically stable TAH-t subjects, and that patients and lay caregivers can be trained to man...(read more)

SynCardia TAH-t PM Surveillance Study
Study Status: Active/Enrolling
Investigator: Bruckner, Brian
Study Coordinator: Bunge, Raquel
Phone: 713-441-6509
Summary:The purpose of this study is to demonstrate that the results achieved in the original pivotal clinical investigation of 81 subjects from five clinical sites are generalizable to new clinical sites tha...(read more)
Kidney Transplant

Angion
Study Status: Active/Enrolling
Investigator: Gaber, Ahmed
Study Coordinator: Brann, Sarah
Phone: 713-441-6394
Summary:The objective of the study is to evaluate the safety and activity of a investigational drug in improving renal function in patients who have undergone renal transplantation and have signs and symptoms...(read more)

Eculizumab in the Prevention of A.M.R.
Study Status: Active/Enrolling
Investigator: Gaber, Ahmed
Study Coordinator: Brann, Sarah
Phone: 713-441-6394
Summary:The purpose of this trial is to determine the safety and efficacy of eculizumab in the prevention of antibody mediated rejection (AMR) in living donor kidney recipients requiring desensitization thera...(read more)

LCP-Tacro 3002
Study Status: Active/Enrolling
Investigator: Knight, Richard
Study Coordinator: Brann, Sarah
Phone: 713-441-6394
Summary:This study will evaluate the efficacy and safety of LCP-Tacro (tacrolimus) Tablets administered once-a-day compared to Prograf (tacrolimus) Capsules twice-a-day as immunosuppression for the prevention...(read more)

Single dose vs Traditional Administration Thymoglobulin (S.T.A.T.)
Study Status: Active/Enrolling
Investigator: Gaber, Ahmed
Study Coordinator: Brann, Sarah
Phone: 713-441-6394
Summary:In a non-blinded pilot study conducted at the University of Nebraska Medical Center, evidence was found that a single large dose of Thymoglobulin on the day of kidney transplantation produced better k...(read more)
Liver Transplant

Salix: Rifaximin / Hepatic Encephalopathy study
Study Status: Active/Enrolling
Investigator: Monsour, Howard
Study Coordinator: Dorman, Susan
Phone: 713-441-6316
Summary:The purpose of the study is to evaluate the safety of Rifaximin or placebo in subjects with severe hepatic impairment and Hepatic Encephalopathy.(read more)
Medical Devices

Fistula Plug for Use in Anal Fistula Repair
Study Status: Active/Enrolling
Investigator: Bailey, H. Randolph
Study Coordinator: Cleere, Darrel
Phone: 713-441-6232
Summary:The primary purpose of this prospective, multicenter, observational, single arm study is to substantiate efficacy of the GORE® BIO-A® Fistula Plug when used as a soft tissue reinforcement of anal fist...(read more)
Transplant Related Viral Infections

Cipro for BK Prophylaxis
Study Status: Active/Enrolling
Investigator: Patel, Samir
Study Coordinator: Kueser, Mary
Phone: 7134416311
Summary:BK infection is an important cause of graft dysfunction and graft loss after renal transplantation. It has been widely accepted that emergence of BK virus correlates with the more potent immunosuppres...(read more)