David M. Brown, M.D.
Medical/Surgical Internship, Baylor College of Medicine, Houston, TX
After completing his postdoctoral training, Dr. Brown joined the faculty at the Baylor College of Medicine as a Clinical Instructor in the Department of Ophthalmology. He received his faculty appointment at the Weill Medical College in 2006.
Dr. Brown’s research centers on clinical investigations to evaluate treatments for diabetic retinopathy, neovascular age-related macular degeneration, central retinal vein occlusion, and retinal detachment. Dr. Brown was a key investigator on the Anti-VEGF Antibody for the Treatment of Predominantly Classic Choroidal Neovascularization in Age-related Macular Degeneration (ANCHOR) Study and the Minimally classic/occult trial of the anti-VEGF antibody ranibizumab in the treatment of neovascular AMD (MARINA) Study which both demonstrated a statistically significant benefit of Lucentis (ranibizumab) over Visudyne (verteporfin photodynamic therapy [PDT]) in predominantly classic choroidal neovascularization (CNV). Dr. Brown is also a member of the Diabetic Retinopathy Clinical Research Network.
Diabetic retinopathy, neovascular age-related macular degeneration, central retinal vein occlusion, retinal detachment
Kaiser PK, Brown DM, Zhang K, Hudson HL, Holz FG, Shapiro H, Schneider S, Acharya NR. Ranibizumab for predominantly classic neovascular age-related macular degeneration: Subgroup analysis of first-year ANCHOR results. Am J Ophthalmol. 2007;144(6): 850-857.
Brown DM, Regillo CD. Anti-VEGF agents in the treatment of neovascular age-related macular degeneration: applying clinical trial results to treatment of everyday patients. Am J Ophthalmol. 2007:144(6): 627-637.
Diabetic Retinopathy Clinical Research Network, Browning DJ, Glassman AR, Aiello LP, Beck RW, Brown DM, Fong DS, Bressler NM, Danis RP, Kinyoun JL, Nguyen QD, Bhavsar AR, Gottlieb J, Pieramici DJ, Rauser ME, Apte RS, Lim JI, Miskala PH. Relationship between optical coherence tomography-measured central retina thickness and visual acuity in diabetic macular edema. Ophthalmology. 2007; 114(3): 525-536.
Brown DM, Kaiser PK, Michels M, Soubrane G, Heier JS, Kim RY, Sy JP, Schneider S: ANCHOR Study Group. Ranibizumab versus verteporfin for neovascular age-related macular degeneration. N Engl J Med. 2006;355(14):1432-1444.
Rosenfeld PJ, Brown DM, Heier JS, Boyer DS, Kaiser PK, Chung CY, Kim RY: MARINA Study Group. Ranibizumab for neovascular age-related macular degeneration. N Engl J Med. 2006;355(14):1419-1431.