Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Alberto G. Ayala, M.D.

Alberto G. Ayala, M.D.


Alberto G. Ayala, M.D.

Alberto G. Ayala, M.D.

Senior Member
The Methodist Hospital Research Institute
Deputy Chief of Pathology
Department of Pathology and Laboratory Medicine
The Methodist Hospital Physician Organization
Professor of Pathology and Genomicf Medicine
Weill Cornell Medical College of Cornell University

E-mail: aayala@houstonmethodist.org
Phone: 713-441-1339
Fax: 713-793-1603


B.A.   Escuela de Bachilleres, University of Nuevo Leon, Monterrey, N.L., Mexico
M.D.   School of Medicine, University of Nuevo Leon, Monterrey, N.L., Mexico
M.D.   Facultad de Medicina, Awarded M.D., Universidad de Nuevo Leon, Monterrey, Mexico

Postdoctoral Training

Residency, John Seely Hospital, University of Texas Medical Branch, Galveston, TX
Pathology Fellowship, University of Texas M.D. Anderson Cancer Center, Houston, TX



Shortly after completing a pathology fellowship at the M.D. Anderson Cancer Center in 1968, he joined the faculty there as an Assistant Professor. He stayed at the institution for 33 years, rising quickly through the academic ranks and earning numerous awards and accolades, including the Charles A. LeMaistre, MD Outstanding Achievement Award in Cancer. Dr. Ayala also held several leadership positions there, including Director of Surgical Pathology, Deputy Chairman of the Department of Anatomic Pathology, and Interim Head of the Division of Pathology. He assumed his current positions at Methodist in 2004.

Description of Research

Dr. Ayala’s research focuses on the pathogenesis of carcinomas of the lung, kidneys and ovaries.

Major Areas of Research

Carcinoma, lung, renal.

Recent Publications

Harvey AM, Grice B, Hamilton C, Truong LD, Ro JY, Ayala AG, Zhai QJ. Diagnostic utility of P504S/p63 cocktail, prostate-specific antigen, and prostatic acid phosphatase in verifying prostatic carcinoma involvement in seminal vesicles: a study of 57 cases of radical prostatectomy specimens of pathologic stage pT3b. Arch Pathol Lab Med. 2010 Jul;134(7):983-8.

Kim J, Kumar R, Raymond AK, Ayala AG. Non-epiphyseal chondroblastoma arising in the iliac bone, and complicated by an aneurysmal bone cyst: a case report and review of the literature. Skeletal Radiol. 2010 Jun;39(6):583-7.

Ge Y, Luna MA, Cowan DF, Truong LD, Ayala AG. Thyrolipoma and thyrolipomatosis: 5 case reports and historical review of the literature. Ann Diagn Pathol. 2009 Dec;13(6):384-9. Review.

Quiroga-Garza G, Khurana H, Shen S, Ayala AG, Ro JY. Sarcomatoid chromophobe renal cell carcinoma with heterologous sarcomatoid elements. A case report and review of the literature. Arch Pathol Lab Med. 2009 Nov;133(11):1857-60.

Song JS, Gardner JM, Tarrant WP, Shen S, Ayala AG, Yu E, Ro JY. Dedifferentiated liposarcoma with peculiar meningothelial-like whorling and metaplastic bone formation. Ann Diagn Pathol. 2009 Aug;13(4):278-84. Review.

Kim HJ, Shen SS, Ayala AG, Ro JY, Truong LD, Alvarez K, Bridge JA, Gatalica Z, Hagenkord JM, Gonzalez-Berjon JM, Monzon FA. Virtual-karyotyping with SNP microarrays in morphologically challenging renal cell neoplasms: a practical and useful diagnostic modality. Am J Surg Pathol. 2009 Sep;33(9):1276-86.

Suh JH, Oak T, Ro JY, Truong LD, Ayala AG, Shen SS. Clinicopathologic features of renal cell carcinoma in young adults: a comparison study with renal cell carcinoma in older patients. Int J Clin Exp Pathol. 2009;2(5):489-93.

Dayton AS, Ro JY, Schwartz MR, Ayala AG, Raymond AK. Raymond's Paragraph System: an alternative format for the organization of gross pathology reports and its implementation in an academic teaching hospital. Arch Pathol Lab Med. 2009 Feb;133(2):298-302. Review.