Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

John J. Mahmarian, M.D.

John J. Mahmarian, M.D.


John J. Mahmarian, M.D.

John J. Mahmarian, M.D.

Senior Member
The Methodist Hospital Research Institute

Chief, Division of Nuclear Cardiology and CT Services
Methodist DeBakey Heart and Vascular Center
The Methodist Hospital

Professor of Medicine 
Weill Cornell Medical College of Cornell University

Phone: 713-441-1100
Fax: 713-793-7034


B.S.   Duke University, Durham, NC (Zoology)
M.D.   New York Medical College, Valhalla, New York

Postdoctoral Training

Internship, Baylor College of Medicine Affiliated Hospitals, Houston, TX
Internal Medicine Residency, Baylor College of Medicine, Houston, TX
Cardiology Fellowship, Baylor College of Medicine, Houston, TX
Nuclear Cardiology Fellowship, Baylor College of Medicine, Houston, TX



Dr. Mahmarian received his first faculty appointment in 1987 as an Instructor of Medicine at the Baylor College of Medicine in Houston, Texas. He quickly established himself as a leader in nuclear cardiology research and was promoted to full Professor in 2005 just prior to joining the Methodist Hospital Physician Organization and the faculty of the Weill Medical College of Cornell University.

Description of Research

Dr. Mahmarian´s early research efforts focused on quantification of ischemia as measured by SPECT sestimibi, thereby laying the groundwork for the use of this technique in international trials of ischemia. His current research is focused on combining the results of CT acquired coronary angiography with SPECT results (fusion imaging), as well as testing new agents for pharmacologic stress testing and imaging modalities (e.g. "hot spot" imaging).

Major Areas of Research

Nuclear cardiology, ischemia, imaging, CT, SPECT, stress testing

Recent Publications

Friedewald VE, Iskandrian AE, Mahmarian JJ, Roberts WC.The Editor´s Roundtable: Advances in Myocardial Perfusion Imaging. Am J Cardiol. 2009 Mar 1;103(5):680-687. No abstract available.

Iskandrian AE, Garcia EV, Faber T, Mahmarian JJ. Automated assessment of serial SPECT myocardial perfusion images. J Nucl Cardiol. 2009 Jan-Feb;16(1):6-9. Epub 2009 Jan 20. No abstract available.

Venkataraman R, Heo J, Hendel RC, Mahmarian JJ, Iskandrian AE. The role of first-pass radionuclide angiography in the era of gated SPECT myocardial perfusion imaging. J Nucl Cardiol. 2008 Nov-Dec;15(6):838-40. Epub 2008 Sep 7. No abstract available.

Hansen CL, Goldstein RA, Akinboboye OO, Berman DS, Botvinick EH, Churchwell KB, Cooke CD, Corbett JR, Cullom SJ, Dahlberg ST, Druz RS, Ficaro EP, Galt JR, Garg RK, Germano G, Heller GV, Henzlova MJ, Hyun MC, Johnson LL, Mann A, McCallister BD Jr, Quaife RA, Ruddy TD, Sundaram SN, Taillefer R, Ward RP, Mahmarian JJ; American Society of Nuclear Cardiology. Myocardial perfusion and function: single photon emission computed tomography. J Nucl Cardiol. 2007 Nov-Dec;14(6):e39-60. Review. No abstract available.

Mahmarian JJ.Computed tomography coronary angiography as an anatomic basis for risk stratification: déjá vu or something new? J Am Coll Cardiol. 2007 Sep 18;50(12):1171-3. Epub 2007 Sep 4. No abstract available.