Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Publications

Publications

Recent Publications of Stanley H. Appel, M.D.

Wheaton MW, Salamone AR, Mosnik DM, McDonald RO, Appel SH, Schmolck HI, Ringholz GM, Schulz PE. Cognitive impairment in familial ALS. Neurology. 2007 Oct 2;69(14):1411-7.

Voustianiouk A, Seidel G, Panchal J, Sivak M, Czaplinski A, Yen A, Appel SH, Lange DJ. ALSFRS and Appel ALS scores: discordance with disease progression. Muscle Nerve. 2008 May;37(5):668-72.

Appel SH, Beers DR, Henkel JS, Zhao W. Novel Therapeutic Targets in Neurodegenerative Diseases: Lessons from Amyotrophic Lateral Sclerosis. Curr Neurol Neurosci Rep. 2008 Sep;8(5):353-5.

Beers DR, Henkel JS, Zhao W, Wang J, Appel SH. CD4+T-cells Support Glial Neuroprotection, Slow Disease Progression, and Modify Glial Morphology in an Animal Model of Inherited ALS. Pro Natl Acad Sci USA. 2008, Oct. 7;105(40):15558-63.

Villoslada P, Moreno B, Melero I, Pablos JL, Martino G, Uccelli A, Montalban X, Avila J, Rivest S, Acarin L, Appel S, Khoury SJ, McGeer P, Ferrer I, Delgado M, Obeso J, Schwartz M. Immunotherapy for neurological diseases. Clin Immunol. 2008 Sep;128(3):294-305.

Recent Publications of David R. Beers, PhD

Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH. Mutant SOD1G93A microglia are more neurotoxic relative to wild-type microglia. J Neurochem. 2007;102(6):2008-2019.

Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc Natl Acad Sci USA. 2006;103(43):16021-16026.

Zhao W, Xie W, Xiao Q, Beers DR, Appel SH. Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia. J Neurochem. 2006;99(4):1176-1187.

Henkel JS, Beers DR, Siklos L, Appel SH. The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol Cell Neurosci. 2006;31(3):427-437.

Zhao W, Xie W, Le W, Beers DR, He Y, Henkel JS, Simpson EP, Yen AA, Xiao Q, Appel SH. Activated microglia initiate motor neuron injury by a nitrite oxide and glutamate-mediated mechanism. J Neuropathol Exp Neurol. 2004;63(9):964-977.

Recent Publications of Jenny S. Henkel, Ph.D.

Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH. SOD1G93A microglia are more neurotoxic relative to wild-type microglia. J Neurochem. 2007;102(6): 2008-2019.

Beers DR*, Henkel JS*, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH. Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc Natl Acad Sci USA.2006;103(43):16021-16026.

Henkel JS, Beers DR, Siklos L, Appel SH. The chemokine MCP-1 and the dendritic and myeloid cells it attracts are increased in the mSOD1 mouse model of ALS. Mol Cell Neurosci. 2006;31(3):427-437.

Henkel JS, Engelhardt JI, Siklos L, Simpson EP, Kim SH, Pan T, Goodman JC, Siddique T, Beers DR, Appel SH. Presence of dendritic cells, MCP-1, and activated microglia/macrophages in amyotrophic lateral sclerosis spinal cord tissue. Ann Neurol. 2004;55(2):221-235.

Kim SH, Henkel JS, Beers DR, Sengun IS, Simpson EP, Goodman JC, Engelhardt JI, Siklos L, Appel SH. PARP expression is increased in astrocytes but decreased in motor neurons in the spinal cord of sporadic ALS patients. J Neuropathol Exp Neurol. 2003; 62:88-103.

Recent Publications of Weihua Zhao, M.D., Ph.D.

Xiao Q, Zhao W, Beers DR, Yen AA, Xie W, Henkel JS, Appel SH. (2007) Mutant SOD1(G93A) microglia are more neurotoxic relative to wild-type microglia. J Neurochem 102:2008-19.

Beers DR, Henkel JS, Xiao Q, Zhao W, Wang J, Yen AA, Siklos L, McKercher SR, Appel SH. (2006) Wild-type microglia extend survival in PU.1 knockout mice with familial amyotrophic lateral sclerosis. Proc Natl Acad Sci U S A 103:16021-6.

Zhao W, Xie W, Xiao Q, Beers DR, Appel SH. (2006) Protective effects of an anti-inflammatory cytokine, interleukin-4, on motoneuron toxicity induced by activated microglia. J Neurochem 99:1176-87.

Zhao W, Xie W, Le W, Beers DR, He Y, Henkel JS, Simpson EP, Yen AA, Xiao Q, Appel SH. (2004) Activated microglia initiate motor neuron injury by a nitric oxide and glutamate-mediated mechanism. J Neuropathol Exp Neurol 63:964-77.

Recent Publications of Bing Liao Ph.D

PINK1 and Parkinson’s disease. Review. First author. Chinese Journal of Neurology. 2007.2

Mutation analysis of Parkin, PINK1, DJ-1 and ATP13A2 genes in Chinese patients with autosomal recessive early-onset Parkinsonism. Third author. Mov Disord. 2008 Oct 30;23(14):2074-9.

Recent Publications of Osamu Kano M.D., Ph.D

Igarashi O, Ogura N, Kiyozuka T, Kawabe K, Iguchi H, Maruyama M, Fujioka T, Ichikawa Y, Ikeda K, Iwasaki Y. Lateral lower medullary infarction. Arch Neurol. 2004 Oct;61(10):1609.

Igarashi O, Aoyagi J, Kawase Y, Kiyozuka T, Kawabe K, Ichikawa Y, Iguchi H, Fujioka T, Ikeda K, Iwasaki Y. Cheiro-pedal syndrome following pontine infarction. Neurol Res. 2005 Jan;27(1): 103-4

Igarashi O, Ikeda K, Iwasaki Y. The relation between trace elements and amyotrophic lateral sclerosis. Biomedical Research on Trace Elements. 2005;16:9-11

Igarashi O, Iguchi H, Ogura N, Ichikawa Y, Kiyozuka T, Kawabe K, Maruyama M, Fujioka T, Ikeda K, Iwasaki Y. Cheiro-oral-pedal syndrome due to brainstem hemorrhage. Clin Neurol Neurosurg. 2006 Jul;108(5):507-10

Arasaki K, Igarashi O, Ichikawa Y, Machida T, Shirozu I, Hyodo A, Ushijima R. Reduction in the motor unit number estimate (MUNE) after cerebral infarction. J Neurol Sci. 2006;250(1-2):27-32

Recent Publications of Shixiang Wen B.S.

Xinwen Wang, Scott A. LeMaire, Lori D. Conklin, Shixiang Wen, Weiping Fu, and Joseph S. Coselli, Differing patterns of matrix metalloproteinase expression in patients with ascending aortic aneurysms and bicuspid aortic valves. J Surg Res 2003; 114: 255.

Scott A. LeMaire, Jonathan Wilks, Xinwen Wang, Stacey Carter ,Shixiang Wen, Lori D. Conklin, XinLi Wang, Joseph S. Coselli. Matrix metalloproteinases in ascending aortic aneurysms: bicuspid vs. trileaflet aortic valves. J Surg Res 2004; in press.

Scott A. LeMaire, Xinwen Wang, Shixiang Wen, Stacey Carter, Joseph S. Coselli. Deployment of balloon expandable stents during open repair of thoracoabdominal aortic aneurysms: a new strategy for managing renal and mesenteric artery lesions. Eur J Cardio-thorac Surg 2004; in press.

Xiujun Zhang, Yi Zhao, Shixiang Wen. 1998 An Improved Medium for the Protoplast Regeneration of Antibiotic 5102 Producing Streptomyces hygroscopicus J. Hubei Agricultural University 1998,18(4):347-348

Xiujun Zhang, Shixiang Wen, Yi Zhao, Qi Zhou. 1996 Screening biological control agents by germinating carrot seeds -- a rapid and effective method. Advances in Biological Control of Plant Disease. China Agricultural University Press 1996 5 140-145