Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Genomic Medicine


The Genomic Medicine program includes research teams studying nuclear hormone receptor structure and function, and the actions of pharmaceutical agents that target hormone receptors for treatment of metabolic diseases. Research approaches include X-ray structural analysis, targeted mutagenesis to understand receptor structure, detailed analysis of gene expression and genome wide sequence interactions and collaborative studies to determine the metabolic effects of drugs in preclinical models, and nuclear hormone receptor genomic regulatory mechanisms. The program is closely associated with the Genomic Sequencing Core facility which supports this research.