Showing 1-10 of 20 "Coronary Artery Disease"

Status: Enrolling

Investigator: Alpesh Shah

Study Coordinator: Saba Khan

Phone: 713.441.2116

A Clinical Evaluation of Absorb™ BVS, the Everolimus Eluting Bioresorbable Vascular Scaffold in the Treatment of Subjects with de novo Native Coronary Artery Lesions This is a prospective, randomized, single-blind, multi-center trial, conducte ... Read more >

Status: Open Not Enrolling

Investigator: Byron Ellis

Study Coordinator: Sheila Moore

Phone: 713.441.3250

Current patterns of P2Y12 receptor inhibitor use provide an excellent opportunity to test the impact of copayment reduction on clinician choice of medication, patient adherence, and clinical outcomes. The ARTEMIS trial is a practical multicenter ... Read more >

Status: Enrolling

Investigator: Colin Barker

Study Coordinator: LaShawna Green

Phone: 713.441.6548

The objective of this study is to assess the safety and efficacy of the Orsiro Sirolimus Eluting Coronary Stent System in the treatment of subjects with up to three native de novo or restenotic (standard PTCA only) coronary artery lesions compar ... Read more >

Status: Enrolling

Investigator: Neal Kleiman

Study Coordinator: Pamela Hazen

Phone: 713.441.9716

This is a prospective, randomized, parallel-controlled, multicenter clinical evaluation of the MitraClip device for the treatment of clinically significant functional mitral regurgitation in symptomatic subjects too high risk to undergo mitral v ... Read more >

Status: Open Not Enrolling

Investigator: Alpesh Shah

Study Coordinator: Mary Mata

Phone: 713.441.5981

This is a prospective, multi-center, non-randomized, single arm clinical trial that will be conducted at up to 40 sites in the United States and OUS. A minimum of 40% of total patients will be enrolled in the US. This study will enroll patient ... Read more >

Status: Open Not Enrolling

Investigator: Neal Kleiman

Study Coordinator: LaShawna Green

Phone: 713.441.6548

The study is being done study to obtain data on the safety and performance of the Medtronic CoreValve® System. The Medtronic CoreValve® System has been developed to replace a diseased aortic heart valve without the need for open heart surgery. T ... Read more >

Status: Enrolling

Investigator: Neal Kleiman

Study Coordinator: LaShawna Green

Phone: 713.441.6548

The primary objective of the study is to evaluate the safety and effectiveness of the Medtronic CoreValve® System (MCS) in a subset of subjects excluded from the U.S. Extreme Risk Pivotal Trial population due to one or more additional co-morbidi ... Read more >

Status: Open Not Enrolling

Investigator: Neal Kleiman

Study Coordinator: LaShawna Green

Phone: 713.441.6548

To evaluate the safety and efficacy of the CoreValve Evolut R System in patients with severe symptomatic aortic stenosis who are considered at high through extreme risk for surgical aortic valve replacement ... Read more >

Status: Open Not Enrolling

Investigator: Alpesh Shah

Study Coordinator: Mary Mata

Phone: 713.441.5981

To establish the safety and efficacy of the XIENCE PRIME or XIENCE V Everolimus Eluting Coronary Stent System (EECSS) in subjects with unprotected left main coronary artery disease by comparing to coronary artery bypass graft surgery ... Read more >

Status: Enrolling

Investigator: Alpesh Shah

Study Coordinator: Mary Mata

Phone: 713.441.5981

The purpose of the EXPERT CTO clinical trial is to continue to evaluate the safety and effectiveness of the XIENCE V Everolimus Eluting Coronary Stent System and the XIENCE nano Everolimus Eluting Coronary Stent System, manufactured by Abbott Va ... Read more >

Status: Enrolling

Investigator: Alpesh Shah

Study Coordinator: Pamela Hazen

Phone: 713.441.9716

The purpose of this study is to determine whether Fractional flow reserve (FFR, (coronary pressure wire-based index for assessing the ischemic potential of a coronary lesion)-guided percutaneous coronary intervention (PCI) in patients with multi ... Read more >

Status: Enrolling

Investigator: Alpesh Shah

Study Coordinator: Mary Mata

Phone: 713.441.5981

The purpose of this study is to evaluate acute and long term clinical and economic outcomes of endovascular procedures to treat Peripheral Arterial Disease (PAD) ... Read more >

Status: Enrolling

Investigator: Alpesh Shah

Study Coordinator: Mary Mata

Phone: 713.441.5981

The two objectives of the study are to assess the current standard of care treatment outcome in none/mild, moderate and severe calcified coronary lesions and to obtain financial data and procedure data to support reimbursement initiatives and he ... Read more >

Status: Enrolling

Investigator: Neal Kleiman

Study Coordinator: Lisa Green

Phone: 713.441.3100

The primary objective of the combined Phase I&II is to evaluate the reasonable assurance of safety and effectiveness of the CKI Parachute implant in the treatment of patients with NYHA Class III or IV(AMBULATORY) heart failure due to ischemic he ... Read more >

Status: Open Not Enrolling

Investigator: Dipan Shah

Study Coordinator: Saba Syed

Phone: 512.909.7480

This is a single center, open-label, pilot study in subjects scheduled for invasive coronary angiography for evaluation of coronary artery disease. The primary objective is to evaluate the profile of sensitivity, specificity, and diagnostic accu ... Read more >

Status: Enrolling

Investigator: Su Min Chang

Study Coordinator: Christopher Mattair

Phone: 713.363.9956

The aim of this study is to compare the image quality of the half radioisotope dose scans obtained using a CZT (cadmium zinc telluride) camera with scans acquired using a standard of care imaging protocol/radioisotope dose performed on a traditi ... Read more >

Status: Enrolling

Investigator: Neal Kleiman

Study Coordinator: LaShawna Green

Phone: 713.441.6548

The objective of this study is to evaluate the safety and effectiveness of the Lotus™ Valve System for transcatheter aortic valve replacement (TAVR) in symptomatic subjects with calcific, severe native aortic stenosis who are considered at extre ... Read more >

Status: Enrolling

Investigator: Neal Kleiman

Study Coordinator: LaShawna Green

Phone: 713.441.6548

A study to assess the safety and effectiveness of the Direct Flow Medical aortic valve system. This is for people with severe aortic stenosis who are not well enough to undergo a surgical repair. The delivery of this device is done via the femor ... Read more >

Status: Enrolling

Investigator: Neal Kleiman

Study Coordinator: LaShawna Green

Phone: 713.441.6548

The purpose of the study is to investigate the safety and efficacy of transcatheter aortic valve implantation (TAVI) in patients with severe, symptomatic Aortic Stenosis (AS) at intermediate surgical risk by randomizing patients to either Surgic ... Read more >

Status: Open Not Enrolling

Investigator: Colin Barker

Study Coordinator: Kim Donlon

Phone: 713.441.9394

The Symplicity HTN-3 study is a, multi-center, prospective, single-blind, randomized, controlled study of the safety and effectiveness of renal denervation in subjects with uncontrolled hypertension. Bilateral renal denervation will be performed ... Read more >