Showing 1-4 of 4 "Brain and Central Nervous System Cancers"

Status: Open Not Enrolling

Investigator: David Baskin

Study Coordinator: Pamela Weaver

Phone: 713.441.3834

Purpose This is a multicenter, open-label, ascending-dose trial of the safety and tolerability of increasing doses of Toca 511, a Retroviral Replicating Vector (RRV), administered to subjects with recurrent high grade glioma (rHGG) who have u ... Read more >

Status: Open Not Enrolling

Investigator: David Baskin

Study Coordinator: Pamela Weaver

Phone: 713.441.3834

Purpose The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM for whom surgery is indicated. Patients must enter screening at a participating site pr ... Read more >

Status: Enrolling

Investigator: David Baskin

Study Coordinator: Pamela Weaver

Phone: 713.441.3834

This is a multicenter, randomized, open-label phase 2/3 study of Toca 511 and Toca FC versus standard of care that comprises Investigator's choice of single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects u ... Read more >

Status: Open Not Enrolling

Investigator: David Baskin

Study Coordinator: Julie Baskin

Phone: 713.441.3800

ICT-107 consists of dendritic cells, prepared from autologous mononuclear cells that are pulsed with six synthetic peptides that were derived from tumor associated antigens (TAA) present on glioblastoma tumor cells. This is a Phase 3 study to ev ... Read more >