Showing 1-10 of 11 "Nervous System Diseases "

Status: Open Not Enrolling

Investigator: David Baskin

Study Coordinator: Pamela Weaver

Phone: 713.441.3834

Purpose This is a multicenter, open-label, ascending-dose trial of the safety and tolerability of increasing doses of Toca 511, a Retroviral Replicating Vector (RRV), administered to subjects with recurrent high grade glioma (rHGG) who have u ... Read more >

Status: Open Not Enrolling

Investigator: Orlando Diaz

Study Coordinator: Bhavin Shah

Phone: 832.279.5111

The purpose of this study is to evaluate the safety of the Apollo™ Onyx™ Delivery Micro Catheter used for delivery of the Onyx™ Liquid Embolic System during brain arteriovenous malformation (AVM) embolization procedures. ... Read more >

Status: Enrolling

Investigator: Richard Klucznik

Study Coordinator: Ramon Guardiola

Phone: 713.441.3958

.The primary objective of this study is to demonstrate effectiveness and safety of the NeuroForm Atlas stent system for use with bare metal embolic coils ... Read more >

Status: Enrolling

Investigator: David Chiu

Study Coordinator: Charles McCane

Phone: 713.441.5801

Carotid revascularization for primary prevention of stroke (CREST-2) is two independent multicenter, randomized controlled trials of carotid revascularization and intensive medical management versus medical management alone in patients with asym ... Read more >

Status: Open Not Enrolling

Investigator: Orlando Diaz

Study Coordinator: Ramon Guardiola

Phone: 713.441.3958

The purpose of this study is to evaluate the safety and effectiveness of the MicroVention Flow Redirection Intraluminal Device (FRED) system when used in the treatment of wide-necked intracranial aneurysms. ... Read more >

Status: Open Not Enrolling

Investigator: Joseph Masdeu

Study Coordinator: Jennifer Garrett

Phone: 713.441.9484

The primary objective is to evaluate the efficacy of T-817MA as measured by ADAS-cog and ADCS-CGIC. The secondary objectives are: To evaluate the safety and tolerability of T-817MA measured by clinical safety laboratories, physical examina ... Read more >

Status: Open Not Enrolling

Investigator: David Baskin

Study Coordinator: Pamela Weaver

Phone: 713.441.3834

Purpose The primary purpose of the study is to determine the efficacy of an investigational therapy called DCVax(R)-L in patients with newly diagnosed GBM for whom surgery is indicated. Patients must enter screening at a participating site pr ... Read more >

Status: Enrolling

Investigator: David Baskin

Study Coordinator: Pamela Weaver

Phone: 713.441.3834

This is a multicenter, randomized, open-label phase 2/3 study of Toca 511 and Toca FC versus standard of care that comprises Investigator's choice of single agent chemotherapy (lomustine or temozolomide) or bevacizumab administered to subjects u ... Read more >

Status: Enrolling

Investigator: Eddie Patton

Study Coordinator: Sheila Moore

Phone: 713.441.3250

The purpose of this world-wide prospective parallel-cohort study in patients with relapsing forms of MS, either newly treated with fingolimod or receiving another disease-modifying therapy, is to further explore the incidence of selected safety- ... Read more >

Status: Enrolling

Investigator: David Baskin

Study Coordinator: Julie Baskin

Phone: 713.441.3800

ICT-107 consists of dendritic cells, prepared from autologous mononuclear cells that are pulsed with six synthetic peptides that were derived from tumor associated antigens (TAA) present on glioblastoma tumor cells. This is a Phase 3 study to ev ... Read more >

Status: Open Not Enrolling

Investigator: Orlando Diaz

Study Coordinator: Bhavin Shah

Phone: 832.279.5111

The purpose of this study is to assess the safety and effectiveness of the Pipeline™ device in the treatment of unruptured, wide-neck intracranial aneurysms. ... Read more >