Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Paul Rees Ph.D.

Paul Rees, Ph.D.

Paul Rees, Ph.D.

Paul Rees, Ph.D.


Affiliate Full Member 
Department of Nanomedicine
The Methodist Hospital Research Institute

Professor
College of Engineering
Swansea University

E-mail:  p.rees@swansea.ac.uk
Phone: 011-44-1792-295197


Education

Ph.D.   Cardiff University, Cardiff, Wales, UK (Laser Physics)
B.S.   Cardiff University, Cardiff, Wales, UK (Physics)
     

Postdoctoral Training

Research Fellow in Optoelectronics, Trinity College, Dublin, Ireland

 

Biography

Paul Rees received his Ph.D. in physics from Cardiff University. He calculated the optical properties of semiconductor lasers and the measured spontaneous emissions from laser diodes under operating conditions. He was a research fellow in the physics department at Trinity College, Dublin, Ireland, where he studied self-pulsation in laser diodes and the theory of many-body effects in wide band-gap semiconductors. He later joined the School of Informatics, University of Wales, Bangor, UK, where he was appointed senior lecturer.

In 2005, Dr.  Rees was appointed as the chair of nanotechnology in the newly-formed Multidisciplinary Nanotechnology Centre at Swansea University. As an Affiliate Full Member of The Methodist Hospital Research Institute, Dr. Rees collaborates with the nanomedicine department to study the uptake of micro and nanoparticles by biological cells.  Dr. Rees also participates as a mentor for the graduate exchange training program between the Methodist Academy and Swansea University. 

Description of Research

Dr. Rees’ research focuses on the uptake of micro and nanoparticles by biological cells using high throughput imaging techniques such as imaging flow cytometry and multi-field imaging microscopy, the biological process of particle uptake, and the study of dose responses for drug molecules deliv-ered by particulate delivery vectors.

Major Areas of Research

Laser diodes, nonlinear systems and chaos, simulation of cell mitosis, colloidal quantum dot fluorophores

Recent Publications

Filby A, Perucha E, Summers H, Rees P, Chana P, Heck S, Lord GM, Davies D. An imaging flow cytometric method for measuring cell division history and molecular symmetry during mitosis. Cytometry A. 2011 Jul;79(7):496-506. PMID: 21638766

Curtis DJ, Brown MR, Hawkins K, Evans PA,  Lawrence MJ, Rees P, Williams PR. Rheometrical and molecular dynamics simulation studies of incipient clot formation in fibrin-thrombin gels: An activation limited aggregation approach. Journal of Non-Newton- Newtonian Fluid Mechanics, Vol. 166, No. 16, pp 932-938.(2011) doi: 10.1016/j.jnnfm.2011.04.016

Summers HD, Rees P, Holton MD, Brown MR, Chappell SC, Smith PJ, Errington RJ. Statistical analysis of nanoparticle dosing in a dynamic cellular system. Nat Nanotechnol. 2011 Mar;6(3):170-4. PMID: 21258333

Rees P, Brown MR, Summers HD, Holton MD, Errington RJ, Chappell SC, Smith PJ. A transfer function approach to measuring cell inheritance. BMC Syst Biol. 2011 Feb 22;5:31. PMID: 21342507

Brown MR, Summers HD, Rees P, Chappell SC, Silvestre OF, Khan IA, Smith PJ, Errington RJ. Long-term time series analysis of quantum dot encoded cells by deconvolution of the autofluorescence signal. Cytometry A. 2010 Oct;77(10):925-32. PMID: 21290466

Summers HD, Holton MD, Rees P, Williams PM, Thornton CA. Analysis of quantum dot fluorescence stability in primary blood mononuclear cells. Cytometry A. 2010 Oct;77(10):933-9. PMID: 21290467

Brown MR, Summers HD, Rees P, Smith PJ, Chappell SC, Errington RJ. Flow-based cytometric analysis of cell cycle via simulated cell populations. PLoS Comput Biol. 2010 Apr 15;6(4):e1000741. PMID: 20419143

Brown MR, Errington R, Rees P, Williams PR, Wilks SP. A highly efficient algorithm for the generation of random fractal aggregates. Physica D. 229, 1061-1066 (2010). doi: 10.1016/j.physd.2010.02.018

Errington RJ, Brown MR, Silvestre OF, Njoh KL, Chappell SC, Khan IA, Rees P, Wilks SP, Smith PJ, Summers HD. Single cell nanoparticle tracking to model cell cycle dynamics and compartmental inheritance. Cell Cycle. 2010 Jan 1;9(1):121-30. PMID: 20016285

Holton MD, Silvestre OR, Errington RJ, Smith PJ, Matthews DR, Rees P, Summers HD. Stroboscopic fluorescence lifetime imaging. Opt Express. 2009 Mar 30;17(7):5205-16. PMID: 19333284