Houston Methodist. Leading Medicine.
Houston Methodist. Leading Medicine

Jeyarama S. Ananta Narayanan

Jeyarama S. Ananta Narayanan, Ph.D. 

Jeyarama S. Ananta Narayanan, Ph.D.

Jeyarama S. Ananta Narayanan, Ph.D.

Postdoctoral Fellow
The Methodist Hospital Research Institute

E-mail: janantanarayanan@houstonmethodist.org
Phone: 713-441-7451
Fax: 713-790-3033


Education

B.S.   Chemistry, Loyola College, Chennai, India
M.S.   Chemistry, Loyola College, Chennai, India
Ph.D.   Chemistry, Rice University, Houston, United States

Postdoctoral Training

Postdoctoral Fellow, NanoBiomedical Engineering, The Methodist Hospital Research Institute

 

 

Biography

Dr. Ananta joined The Methodist Hospital Research Institute in January, 2011. For his      graduate thesis, he worked on the development of carbon-based nanomaterials as contrast agents for MRI. His research experience includes functionalization and characterization of nanomaterials for biomedical applications. In TMHRI, he is working on developing multifunctional “Theragnostic agents” using nanomaterials.

Description of Research

  • Development of novel imaging contrast agents (optical, MRI, SPECT & PET) and study of their in vitro and in vivo characterization and biodistribution.
  • Imaging and targeted delivery of drugs to arteriosclerosis, breast cancer metastasis and ovarian cancer.
  • Specific sub cellular localization of magnetic nanoparticles.

Major Areas of Research

Magnetic Resonance Imaging, Multimodal Imaging, Cell and Molecular Imaging, Nuclear Imaging.

Recent Publications

Ananta JS, Godin B, Sethi R, Moriggi L, Liu X, Serda RE, Krishnamurthy R, Muthupillai R, Bolskar RD, Helm L, Ferrari M, Wilson LJ, Decuzzi P, et al. Geometrical confinement of gadolinium-based contrast agents in nanoporous particles enhances T1 contrast. Nat Nanotechnol. 2010;5, 815-821.

Ananta J, Matson M, Tang A, Mandal T, Lin S, Wong K, Wong S, Wilson LJ, et al. Single-walled Carbon Nanotube Materials as T2-weighted MRI Contrast Agents. J Phys Chem C. 2009;113, 19369-19372.

Sitharaman B, van der Zande M, Ananta JS, Shi X, Veltien A, Walboomers XF, Wilson LJ, Mikos AG, Heerschap A, Jansen JA, et al. Magnetic resonance imaging studies on gadonanotube-reinforced biodegradable polymer nanocomposites. J Biomedical Materials Research Part A. 2010;93A (4), 1454-1462.

Ananta J, Wilson LJ, et al. Gadonanostructures as Magnetic Resonance Imaging Contrast Agents, invited book chapter in Chemistry of Nanocarbons, T. Akasaka, F. Wudl, S. Nagase Eds., John Wiley & Sons, Ltd, Chichester, UK, 2010;287-300.

Mackeyev Y, Hartman KB, Ananta JS, Lee A, Wilson LJ, et al. Catalytic Synthesis of Amino Acid- and Peptide-Derivatized Gadonanotubes. J Am Chem Soc. 2009;131, 8342-8343.

Faridis S, Mitchell D, Smith KDB, Ananta JS, Wilson LJ, Pautler RG. Assessing transneuronal dysfunction utilizing manganese-enhanced MR (MEMRI). J Magn Res Med. 2008;60(1), 169-175.

Tang M, Ananta JS, Zhao H, Cisneros BT, Lam EY, Wong ST, Wilson LJ, Wong K, et al. Cellular uptake and imaging studies of gadolinium-loaded single-walled carbon nanotubes as MRI contrast agents. Contrast Media Mol Imaging. 2011.

Hassan AA, Chan BT-Y, Tran LA, Hartman KB, Ananta JS, Mackeyev Y, Hu L, Pautler RG, Wilson LJ, and Lee AV, et al. Serine-Derivatized Gadonanotubes as Magnetic Nanoprobes for Intracellular Labeling. Contrast Media Mol Imaging. 2010;5, 34-38.