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Xuewu Liu,

Houston Methodist


Areas Of Expertise

Silicon nanotechnology Drug delivery nanoparticles Theranostics Biological microfluidics
Publications

Enzyme-responsive multistage vector for drug delivery to tumor tissue
Mi, Y, Wolfram, J, Mu, C, Liu, X, Blanco, E, Shen, H & Ferrari, M 2016, Pharmacological Research, vol 113, pp. 92-99. DOI:

In situ growth of fluorescent silicon nanocrystals in a monolithic microcapsule as a photostable, versatile platform
Zhu, G, Huang, Y, Bhave, G, Wang, Y, Hu, Z & Liu, X 2016, Nanoscale, vol 8, no. 34, pp. 15645-15657. DOI:

A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells
Scott, B, Shen, J, Nizzero, S, Boom, K, Persano, S, Mi, Y, Liu, X, Zhao, Y, Blanco, E, Shen, H, Ferrari, M & Wolfram, J 2016, Pharmacological Research, vol 111, pp. 413-421. DOI:

Enhanced performance of macrophage-encapsulated nanoparticle albumin-bound-paclitaxel in hypo-perfused cancer lesions
Leonard, F, Curtis, LT, Yesantharao, P, Tanei, T, Alexander, JF, Wu, M, Lowengrub, J, Liu, X, Ferrari, M, Yokoi, K, Frieboes, HB & Godin, B 2016, Nanoscale, vol 8, no. 25, pp. 12544-12552. DOI:

A pyruvate decarboxylase-mediated therapeutic strategy for mimicking yeast metabolism in cancer cells
Scott, B, Shen, J, Nizzero, S, Boom, K, Persano, S, Mi, Y, Liu, X, Zhao, Y, Blanco, E, Shen, H, Ferrari, M & Wolfram, J 2016, Pharmacological Research.

In Situ Reductive Synthesis of Structural Supported Gold Nanorods in Porous Silicon Particles for Multifunctional Nanovectors
Zhu, G, Liu, JT, Wang, Y, Zhang, D, Guo, Y, Tasciotti, E, Hu, Z & Liu, X 2016, ACS Applied Materials and Interfaces, vol 8, no. 18, pp. 11881-11891. DOI:

An injectable nanoparticle generator enhances delivery of cancer therapeutics
Xu, R, Zhang, G, Mai, J, Deng, X, Segura-Ibarra, V, Wu, S, Shen, J, Liu, H, Hu, Z, Chen, L, Huang, Y, Koay, E, Huang, Y, Liu, J, Ensor, JE, Blanco, E, Liu, X, Ferrari, M & Shen, H 2016, Nature Biotechnology, vol 34, no. 4, pp. 414-418. DOI:

IL-4 Release from a Biomimetic Scaffold for the Temporally Controlled Modulation of Macrophage Response
Minardi, S, Corradetti, B, Taraballi, F, Byun, JH, Cabrera, F, Liu, X, Ferrari, M, Weiner, BK & Tasciotti, E 2016, Annals of Biomedical Engineering, pp. 1-12. DOI:

Cell source determines the immunological impact of biomimetic nanoparticles
Evangelopoulos, M, Parodi, A, Martinez, JO, Yazdi, IK, Cevenini, A, van de Ven, AL, Quattrocchi, N, Boada, C, Taghipour, N, Corbo, C, Brown, BS, Scaria, S, Liu, X, Ferrari, M & Tasciotti, E 2016, Biomaterials, vol 82, pp. 168-177. DOI:

Distinct molecular abnormalities underlie unique clinical features of essential thrombocythemia in children
Fu, R, Liu, D, Cao, Z, Zhu, S, Li, H, Su, H, Zhang, L, Xue, F, Liu, X, Zhang, X, Cheng, T, Yang, R & Zhang, L 2016, Leukemia, vol 30, no. 3, pp. 746-749. DOI:

Redirecting transport of nanoparticle albumin-bound paclitaxel to macrophages enhances therapeutic efficacy against liver metastases
Tanei, T, Leonard, F, Liu, X, Alexander, JF, Saito, Y, Ferrari, M, Godin, B & Yokoi, K 2016, Cancer Research, vol 76, no. 2, pp. 429-439.

A Micro/Nano Composite for Combination Treatment of Melanoma Lung Metastasis
Mi, Y, Mu, C, Wolfram, J, Deng, Z, Hu, T, Liu, X, Blanco, E, Shen, H & Ferrari, M 2016, Advanced Healthcare Materials. DOI:

Microfluidic interactions between red blood cells and drug carriers by image analysis techniques
DApolito, R, Taraballi, F, Minardi, S, Liu, X, Caserta, S, Cevenini, A, Tasciotti, E, Tomaiuolo, G & Guido, S 2016, Medical Engineering and Physics, vol 38, no. 1, pp. 17-23. DOI:

Multistage vector delivery of sulindac and silymarin for prevention of colon cancer
Scavo, MP, Gentile, E, Wolfram, J, Gu, J, Barone, M, Evangelopoulos, M, Martinez, JO, Liu, X, Celia, C, Tasciotti, E, Vilar, E & Shen, H 2015, Colloids and Surfaces B: Biointerfaces, vol 136, pp. 694-703. DOI:

Red blood cells affect the margination of microparticles in synthetic microcapillaries and intravital microcirculation as a function of their size and shape
DApolito, R, Tomaiuolo, G, Taraballi, F, Minardi, S, Kirui, D, Liu, X, Cevenini, A, Palomba, R, Ferrari, M, Salvatore, F, Tasciotti, E & Guido, S 2015, Journal of Controlled Release, vol 217, pp. 263-272. DOI:

PLGA-Mesoporous Silicon Microspheres for the in Vivo Controlled Temporospatial Delivery of Proteins
Minardi, S, Pandolfi, L, Taraballi, F, De Rosa, E, Yazdi, IK, Liu, X, Ferrari, M & Tasciotti, E 2015, ACS Applied Materials and Interfaces, vol 7, no. 30, pp. 16364-16373. DOI:

Porous Silicon Microparticle Potentiates Anti-Tumor Immunity by Enhancing Cross-Presentation and Inducing Type I Interferon Response
Xia, X, Mai, J, Xu, R, Perez, JET, Guevara, ML, Shen, Q, Mu, C, Tung, HY, Corry, DB, Evans, SE, Liu, X, Ferrari, M, Zhang, Z, Li, XC, Wang, RF & Shen, H 2015, Cell Reports, vol 11, no. 6, pp. 957-966. DOI:

Biodegradable silicon nanoneedles delivering nucleic acids intracellularly induce localized in vivo neovascularization
Chiappini, C, De Rosa, E, Martinez, JO, Liu, X, Steele, J, Stevens, MM & Tasciotti, E 2015, Nature Materials, vol 14, no. 5, doi:10.1038/nmat4249, pp. 532-539. DOI:

Silencing of tumor necrosis factor receptor-1 in human lung microvascular endothelial cells using particle platforms for siRNA delivery
Bai, L, Andersson, HA, McConnell, KI, Chan, DL, Hernandez, M, Gonzalez, J, Liu, X, Francesca, SL, Sakamoto, JH & Serda, RE 2015, Current Drug Targets, vol 16, no. 13, A013, pp. 1531-1539.

Multistage nanovectors enhance the delivery of free and encapsulated drugs
Martinez, JO, Evangelopoulos, M, Bhavane, R, Acciardo, S, Salvatore, F, Liu, X, Ferrari, M & Tasciotti, E 2015, Current Drug Targets, vol 16, no. 14, pp. 1582-1590.