Not found

Xiaojun Xia, PhD

Instructor in Nanomedicine, Institute for Academic Medicine
Instructor, Research Institute
Houston Methodist


Publications

Effective concentration of a multi-kinase inhibitor within bone marrow correlates with in vitro cell killing in therapy-resistant chronic myeloid leukemia
Mu, C, Wu, X, Ma, H, Tao, W, Zhang, G, Xia, X, Shen, J, Mai, J, Sun, T, Sun, X, Arlinghaus, RB & Shen, H 2016, Molecular Cancer Therapeutics. DOI:

Features of patients with inflammatory bowel diseases who develop hemophagocytic lymphohistiocytosis
Li, Y, Li, CF, Zhang, J, Xia, XF, Zhou, LY, Liu, JJ, Song, ZQ, Lv, YM, Wang, AY, Zhang, YP, Liang, CF, Shi, YY, Quigley, EM, Huang, YH & Ding, SG 2016, International Journal of Colorectal Disease. DOI:

Retinal synaptic regeneration via microfluidic guiding channels
Su, PJ, Liu, Z, Zhang, K, Han, X, Saito, Y, Xia, X, Yokoi, K, Shen, H & Qin, L 2015, Scientific Reports, vol 5, 13591. DOI:

Porous Silicon Microparticle Potentiates Anti-Tumor Immunity by Enhancing Cross-Presentation and Inducing Type I Interferon Response
Xia, X, Mai, J, Xu, R, Perez, JET, Guevara, ML, Shen, Q, Mu, C, Tung, HY, Corry, DB, Evans, SE, Liu, X, Ferrari, M, Zhang, Z, Li, XC, Wang, RF & Shen, H 2015, Cell Reports, vol 11, no. 6, pp. 957-966. DOI:

Bone marrow endothelium-targeted therapeutics for metastatic breast cancer
Mai, J, Huang, Y, Mu, C, Zhang, G, Xu, R, Guo, X, Xia, X, Volk, DE, Lokesh, GL, Thiviyanathan, V, Gorenstein, DG, Liu, X, Ferrari, M & Shen, H 2014, Journal of Controlled Release, vol 187, pp. 22-29. DOI:

Polycation-functionalized nanoporous silicon particles for gene silencing on breast cancer cells
Zhang, M, Xu, R, Xia, X, Yang, Y, Gu, J, Qin, G, Liu, X, Ferrari, M & Shen, H 2014, Biomaterials, vol 35, no. 1, pp. 423-431. DOI:

An IKKa-Nucleophosmin axis utilizes inflammatory signaling to promote genome integrity
Xia, X, Liu, S, Xiao, Z, Zhu, F, Song, NY, Zhou, M, Liu, B, Shen, J, Nagashima, K, Veenstra, T, Burkett, S, Datla, M, Willette-Brown, J, Shen, H & Hu, Y 2013, Cell Reports, vol 5, no. 5, pp. 1243-1255. DOI:

High capacity nanoporous silicon carrier for systemic delivery of gene silencing therapeutics
Shen, J, Xu, R, Mai, J, Kim, HC, Guo, X, Qin, G, Yang, Y, Wolfram, J, Mu, C, Xia, X, Gu, J, Liu, X, Mao, ZW, Ferrari, M & Shen, H 2013, ACS Nano, vol 7, no. 11, pp. 9867-9880. DOI:

MESOPOROUS SILICON PARTICLES FOR THE PRESENTATION OF TUMOR ANTIGENS AND ADJUVANT FOR ANTI-CANCER IMMUNITY
SERDA RITA, ELENA, MERAZ ISMAIL, MUSTAFA, GU, JIANHUA, XIA, XIAOJUN, SHEN, HAIFA, SUN, TONG & FERRARI, MAURO 2013, , Patent No. US2013195963, IPC No. A61K 39/ 00 A I.

TgMAPK1 is a Toxoplasma gondii MAP kinase that hijacks host MKK3 signals to regulate virulence and interferon-?-mediated nitric oxide production
Brumlik, MJ, Pandeswara, S, Ludwig, SM, Jeansonne, DP, Lacey, MR, Murthy, K, Daniel, BJ, Wang, RF, Thibodeaux, SR, Church, KM, Hurez, V, Kious, MJ, Zhang, B, Alagbala, A, Xia, X & Curiel, TJ 2013, Experimental Parasitology, vol 134, no. 3, pp. 389-399. DOI:

Serum peptidomic biomarkers for pulmonary metastatic melanoma identified by means of a nanopore-based assay
Fan, J, Huang, Y, Finoulst, I, Wu, HJ, Deng, Z, Xu, R, Xia, X, Ferrari, M, Shen, H & Hu, Y 2013, Cancer Letters, vol 334, no. 2, pp. 202-210. DOI:

Multistage Vectored siRNA Targeting Ataxia-Telangiectasia Mutated for Breast Cancer Therapy
Xu, R, Huang, Y, Mai, J, Zhang, G, Guo, X, Xia, X, Koay, EJ, Qin, G, Erm, DR, Li, Q, Liu, X, Ferrari, M & Shen, H 2013, Small, vol 9, no. 9-10, pp. 1799-1808. DOI:

Mouse genetic models reveal surprising functions of I?B kinase alpha in skin development and skin carcinogenesis
Xia, X, Park, E, Fischer, SM & Hu, Y 2013, Cancers, vol 5, no. 1, pp. 170-183. DOI:

TAK1 Negatively Regulates NF-?B and p38 MAP Kinase Activation in Gr-1 +CD11b + Neutrophils
Alagbala Ajibade, A, Wang, Q, Cui, J, Zou, J, Xia, X, Wang, M, Tong, Y, Hui, W, Liu, D, Su, B, Wang, HY & Wang, RF 2012, Immunity, vol 36, no. 1, pp. 153. DOI:

TAK1 Negatively Regulates NF-?B and p38 MAP Kinase Activation in Gr-1 +CD11b + Neutrophils
Alagbala Ajibade, A, Wang, Q, Cui, J, Zou, J, Xia, X, Wang, M, Tong, Y, Hui, W, Liu, D, Su, B, Wang, HY & Wang, RF 2012, Immunity, vol 36, no. 1, pp. 43-54. DOI:

NLRX1 Negatively Regulates TLR-Induced NF-?B Signaling by Targeting TRAF6 and IKK
Xia, X, Cui, J, Wang, HY, Zhu, L, Matsueda, S, Wang, Q, Yang, X, Hong, J, Songyang, Z, Chen, ZJ & Wang, RF 2011, Immunity, vol 34, no. 6, pp. 843-853. DOI:

Role of IKKa in skin squamous cell carcinomas
Park, E, Liu, B, Xia, X, Zhu, F, Jami, WB & Hu, Y 2011, Future Oncology, vol 7, no. 1, pp. 123-134. DOI:

Reduction of IKKa expression promotes chronic ultraviolet B exposure-induced skin inflammation and carcinogenesis
Xia, X, Park, E, Liu, B, Willette-Brown, J, Gong, W, Wang, J, Mitchell, D, Fischer, SM & Hu, Y 2010, American Journal of Pathology, vol 176, no. 5, pp. 2500-2508. DOI:

NLRC5 Negatively regulates the NF-?B and type I interferon signaling pathways
Cui, J, Zhu, L, Xia, X, Wang, HY, Legras, X, Hong, J, Ji, J, Shen, P, Zheng, S, Chen, ZJ & Wang, RF 2010, Cell, vol 141, no. 3, pp. 483-496. DOI:

Critical role of I?B kinase alpha in embryonic skin development and skin carcinogenesis
Zhu, F, Park, E, Liu, B, Xia, X, Fischer, SM & Hu, Y 2009, Histology and Histopathology, vol 24, no. 2, pp. 265-271.