Professor of Transplant Immunology in Surgery, Institute for Academic Medicine
Full Member, Research Institute
Director, Immunobiology & Transplant Science Center
Weill Cornell Medical College
Dr. Xian C. Li is the director of the Immunobiology & Transplant Science Center at Houston Methodist Research Institute. Dr. Li served as deputy director of the Transplant Research Center at the Brigham and Women’s Hospital, a teaching hospital of Harvard Medical School before joining Houston Methodist. Dr. Li completed his medical training in China before joining the transplant team at London Health Science Center and the University of Western Ontario in Canada to do his doctoral training in transplant immunology. He then joined the research team at Harvard Medical School and Beth Israel Deaconess Medical Center in Boston, serving on the faculty until 2012.
Dr. Xian C. Li’s lab studies the fundamental mechanisms of transplant rejection and transplant tolerance, the goal of his team is to re-educate patients’ immune system to accept organ transplants without taking life-long immunosuppressive drugs.
Dr. Li has published more than 100 original papers, review articles, and book chapters in high impact journals. He is routinely invited to speak and serves on leadership committees for national and international scientific meetings. He has received awards in recognition of his contribution to transplant immunology including the American Society of Transplantation Young Investigator Award, the American Society of Transplantation Wyeth Basic Science Investigator Award, and AST/Wyeth Achievement Award.
Dr. Li is active in professional organizations and has served as a committee member for the basic science advisory council and grants executive committee of the American Society of Transplantation, a standing member of the American Association of Immunologists and The Transplantation Society, a member of Faculty 1000 for Immunology. He is also an elected member of the American Society for Clinical Investigation, has served as an associate editor for the Journal of Immunology, and is a standing member of the NIH Transplantation, Tolerance and Tumor Immunology study section. He serves on the editorial boards of Transplantation, Transplantation Research, and Cellular & Molecular Immunology.
Dr. Li’s research program seeks to identify new mechanisms and pathways that control immune activation and immune regulation. His team develops new therapeutic protocols that support transplant survival without life-long immunosuppression. His lab has identified several molecular pathways that are critical to the immune recognition of transplants.
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