William G. Ondo, MD

Professor of Neurology, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Biography

Dr. William G. Ondo is the director of the Movement Disorders Clinic at the Houston Methodist Neurological Institute. Dr. Ondo has been in practice for nearly 20 years and specializes in diagnosis, treatment and research of Parkinson’s disease, essential tremors, the use of botulinum toxins in treating movement disorders, and restless legs syndrome.

Dr. Ondo earned his medical degree from the Medical College of Virginia before completing an internship at the University of North Carolina Hospital, a neurology residency at Duke University, and a movement disorders fellowship at the Baylor College of Medicine. He is board certified by the American Board of Psychiatry and Neurology in adult neurology and sleep medicine. He has authored more than 250 original articles and book chapters as well as edited two books on movement disorders. He currently serves as the president of the Tremor Research Group.

Areas Of Expertise

Ataxia Parkinson's disease Dystonia Essential tremor Restless legs
Publications

Clinical and demographic characteristics related to onset site and spread of cervical dystonia
Norris, SA, Jinnah, HA, Espay, AJ, Klein, C, Brüggemann, N, Barbano, RL, Malaty, IAC, Rodriguez, RL, Vidailhet, M, Roze, E, Reich, SG, Berman, BD, LeDoux, MS, Richardson, SP, Agarwal, P, Mari, Z, Ondo, WG, Shih, LC, Fox, SH, Berardelli, A, Testa, CM, Cheng, FCF, Truong, D, Nahab, FB, Xie, T, Hallett, M, Rosen, AR, Wright, LJ & Perlmutter, JS 2016, Movement Disorders, vol 31, no. 12, pp. 1874-1882. DOI:

Knowledge gaps and research recommendations for essential tremor
Hopfner, F, Haubenberger, D, Galpern, WR, Gwinn, K, Vant Veer, A, White, S, Bhatia, K, Adler, CH, Eidelberg, D, Ondo, W, Stebbins, GT, Tanner, CM, Helmich, RC, Lenz, FA, Sillitoe, RV, Vaillancourt, D, Vitek, JL, Louis, ED, Shill, HA, Frosch, MP, Foroud, T, Kuhlenbäumer, G, Singleton, A, Testa, CM, Hallett, M, Elble, R & Deuschl, G 2016, Parkinsonism and Related Disorders, vol 33, pp. 27-35. DOI:

Practice guideline summary: Treatment of restless legs syndrome in adults: Report of the Guideline Development, Dissemination, and Implementation Subcommittee of the American Academy of Neurology
Winkelman, JW, Armstrong, MJ, Allen, RP, Chaudhuri, KR, Ondo, W, Trenkwalder, C, Zee, PC, Gronseth, GS, Gloss, D & Zesiewicz, T 2016, Neurology. DOI:

A randomized trial of focused ultrasound thalamotomy for essential tremor
Elias, WJ, Lipsman, N, Ondo, WG, Ghanouni, P, Kim, YG, Lee, W, Schwartz, M, Hynynen, K, Lozano, AM, Shah, BB, Huss, D, Dallapiazza, RF, Gwinn, R, Witt, J, Ro, S, Eisenberg, HM, Fishman, PS, Gandhi, D, Halpern, CH, Chuang, R, Pauly, KB, Tierney, TS, Hayes, MT, Cosgrove, GR, Yamaguchi, T, Abe, K, Taira, T & Chang, JW 2016, New England Journal of Medicine, vol 375, no. 8, pp. 730-739. DOI:

Guidelines for the first-line treatment of restless legs syndrome/Willis-Ekbom disease, prevention and treatment of dopaminergic augmentation: A combined task force of the IRLSSG, EURLSSG, and the RLS-foundation
Garcia-Borreguero, D, Silber, MH, Winkelman, JW, Högl, B, Bainbridge, J, Buchfuhrer, M, Hadjigeorgiou, G, Inoue, Y, Manconi, M, Oertel, W, Ondo, W, Winkelmann, J & Allen, RP 2016, Sleep Medicine, vol 21, pp. 1-11. DOI:

OnabotulinumtoxinA and AbobotulinumtoxinA Dose Conversion: a Systematic Literature Review
Dashtipour, K, Chen, JJ, Espay, AJ, Mari, Z & Ondo, W 2016, Movement Disorders Clinical Practice, vol 3, no. 2, pp. 109-115. DOI:

Efficacy of gabapentin enacarbil in adult patients with severe primary restless legs syndrome
Lee, DO, Buchfuhrer, MJ, Garcia-Borreguero, D, Avidan, AY, Ahmed, M, Hays, R, Ondo, WG, Jaros, MJ, Kim, R & Shang, G 2016, Sleep Medicine, vol 19, pp. 50-56. DOI:

Essential Tremor: What We Can Learn from Current Pharmacotherapy
Ondo, W 2016, Tremor and other hyperkinetic movements (New York, N.Y.), vol 6, pp. 356. DOI:

Depth and distribution of symptoms in restless legs syndrome/ Willis-Ekbom disease
Yeh, P, Ondo, WG, Picchietti, DL, Steven Poceta, J, Allen, RP, Davies, CR, Wang, L, Shi, Y, Bagai, K & Walters, AS 2016, Journal of Clinical Sleep Medicine, vol 12, no. 12, pp. 1669-1680. DOI:

Post hoc analysis of data from two clinical trials evaluating the minimal clinically important change in international restless legs syndrome sum score in patients with restless legs syndrome (willis-ekbom disease)
Ondo, WG, Grieger, F, Moran, K, Kohnen, R & Roth, T 2016, Journal of Clinical Sleep Medicine, vol 12, no. 1, pp. 63-70. DOI:

Deep brain stimulation (DBS) for severe restless legs syndrome: Therapeutic and physiologic considerations
Ondo, W 2016, Sleep Medicine. DOI:

A novel scale to assess psychosis in patients with parkinson's disease
Ondo, WG, Sarfaraz, S & Lee, M 2015, Journal of clinical movement disorders, vol 2, pp. 17. DOI:

Effect of prior exposure to dopamine agonists on treatment with gabapentin enacarbil in adults with moderate-to-severe primary restless legs syndrome: pooled analyses from 3 randomized trials
Ondo, WG, Hermanowicz, N, Borreguero, DG, Jaros, MJ, Kim, R & Shang, G 2015, Journal of clinical movement disorders, vol 2, pp. 9. DOI:

Does idiopathic restless legs syndrome delay onset and reduce severity of Parkinson's disease: A pilot study
Dragan, EM, Chen, Z & Ondo, WG 2015, International Journal of Neuroscience, vol 125, no. 7, pp. 526-530. DOI:

Deep brain stimulation in other neurological and psychiatric conditions
Ondo, W 2015, . in Deep Brain Stimulation. Nova Science Publishers, Inc. pp. 195-212.

The impact of DaTscan in the diagnosis of Parkinson disease
Gayed, I, Joseph, U, Fanous, M, Wan, D, Schiess, M, Ondo, W & Won, KS 2015, Clinical Nuclear Medicine, vol 40, no. 5, pp. 390-393. DOI:

Clinical characteristics of leg restlessness in Parkinson's disease compared with idiopathic Restless Legs Syndrome
Zhu, XY, Liu, Y, Zhang, XJ, Yang, WH, Feng, Y, Ondo, WG, Tan, EK & Wu, YC 2015, Journal of the Neurological Sciences, vol 357, no. 1-2, pp. 109-114. DOI:

Response to "Shaky legs: More than meets the eyes (or ears)"
Ondo, W 2015, Parkinsonism and Related Disorders, vol 21, no. 2, pp. 163. DOI:

Role of apomorphine in the treatment of Parkinson's Disease
Boyle, A & Ondo, W 2015, CNS Drugs, vol 29, no. 2, pp. 83-89. DOI:

Restless legs syndrome and periodic limb movements in Parkinson’s disease
Ondo, WG 2015, . in Disorders of Sleep and Circadian Rhythms in Parkinsons Disease. Springer-Verlag Vienna, pp. 159-171. DOI: