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William Insull, MD

Professor of Clinical Medicine, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist


Combination of niacin extended-release and simvastatin results in a less atherogenic lipid profile than atorvastatin monotherapy
Insull, W, Toth, PP, Superko, HR, Thakkar, RB, Krause, S, Jiang, P, Parreno, RA & Padley, RJ 2010, Vascular Health and Risk Management, vol 6, no. 1, pp. 1065-1075. DOI:

Efficacy and safety of combination therapy with niacin extended-release and simvastatin versus atorvastatin in patients with dyslipidemia: The SUPREME Study
Insull, W, Basile, JN, Vo, AN, Jiang, P, Thakkar, R & Padley, RJ 2009, Journal of Clinical Lipidology, vol 3, no. 2, pp. 109-118. DOI:

The Pathology of Atherosclerosis: Plaque Development and Plaque Responses to Medical Treatment
Insull, W 2009, American Journal of Medicine, vol 122, no. 1 SUPPL.. DOI:

Insull, W 2009, American Journal of Medicine, vol 122, no. 1 SUPPL.. DOI:

Clinical Management of Atherosclerosis: A Checklist
Insull, W & Lewis, SJ 2009, American Journal of Medicine, vol 122, no. 1 SUPPL.. DOI:

Introduction. Review of major recent findings supporting treatments to control advanced plaques of atherosclerosis.
Insull, W 2009, The American journal of medicine, vol 122, no. 1 Suppl.

Achieving optimal lipid values in patients with dyslipidemia is associated with reduced risk of cardiovascular events
Charland, SL, Cziraky, MJ, Quimbo, R, Karas, RH, Insull, W, Davidson, M & Stanek, EJ 2008, Journal of Clinical Lipidology, vol 2, no. 5, pp. 343-353. DOI:

Achieving low-density lipoprotein cholesterol goals in high-risk patients in managed care: Comparison of rosuvastatin, atorvastatin, and simvastatin in the SOLAR Trial
Insull, W, Ghali, JK, Hassman, DR, Ycas, JW, Gandhi, SK & Miller, E 2007, Mayo Clinic Proceedings, vol 82, no. 5, pp. 543-550. DOI:

Short-term tracking of atherosclerosis in operated and unoperated human carotid arteries by high resolution magnetic resonance imaging
Martin, K, Brownfield, D, Karmonik, C, Sanford, L, Torres, L, Insull, W & Morrisett, J 2007, World Journal of Surgery, vol 31, no. 4, pp. 723-732. DOI:

Dyslipidemia and auditory function
Evans, MB, Tonini, R, Shope, CD, Oghalai, JS, Jerger, JF, Insull, W & Brownell, WE 2006, Otology and Neurotology, vol 27, no. 5, pp. 609-614. DOI:

Clinical utility of bile acid sequestrants in the treatment of dyslipidemia: A scientific review
Insull, W 2006, Southern Medical Journal, vol 99, no. 3, pp. 257-273. DOI:

Treatment of hypercholesterolemia in patients with the metabolic syndrome: How do various statins compare?
Insull, W 2006, Nature Clinical Practice Cardiovascular Medicine, vol 3, no. 3, pp. 134-135. DOI:

Niacin extended-release with lovastatin for hypercholesterolemia
Insull, W 2005, Cardiology Review, vol 22, no. 1, pp. 36-41.

Sample size calculation for clinical trials using magnetic resonance imaging for the quantitative assessment of carotid atherosclerosis
Saam, T, Kerwin, WS, Chu, B, Cai, J, Kampschulte, A, Hatsukami, TS, Zhao, XQ, Polissar, NL, Neradilek, B, Yarnykh, VL, Flemming, K, Huston, J, Insull, W, Morrisett, JD, Rand, SD, Demarco, KJ & Yuan, C 2005, Journal of Cardiovascular Magnetic Resonance, vol 7, no. 5, pp. 799-808. DOI:

Effects of raloxifene and low-dose simvastatin coadministration on plasma lipids in postmenopausal women with primary hypercholesterolemia
Insull, W, Davidson, MH, Kulkarni, PM, Siddhanti, S, Ciaccia, AV & Keech, CA 2005, Metabolism: Clinical and Experimental, vol 54, no. 7, pp. 939-946. DOI:

Feasibility of in vivo, multicontrast-weighted MR imaging of carotid atherosclerosis for multicenter studies
Chu, B, Zhao, XQ, Saam, T, Yarnykh, VL, Kerwin, WS, Flemming, KD, Huston, J, Insull, W, Morrisett, JD, Rand, SD, DeMarco, KJ, Polissar, NL, Balu, N, Cai, J, Kampschulte, A, Hatsukami, TS & Yuan, C 2005, Journal of Magnetic Resonance Imaging, vol 21, no. 6, pp. 809-817. DOI:

Tracking regression and progression of atherosclerosis in human carotid arteries using high-resolution magnetic resonance imaging
Adams, GJ, Greene, J, Vick, GW, Harrist, R, Kimball, KT, Karmonik, C, Ballantyne, CM, Insull, W & Morrisett, JD 2004, Magnetic Resonance Imaging, vol 22, no. 9, pp. 1249-1258. DOI:

Treatment of high-risk patients with ezetimibe plus simvastatin co-administration versus simvastatin alone to attain National Cholesterol Education Program Adult Treatment Panel III Low-Density lipoprotein cholesterol goals
Feldman, T, Koren, M, Insull, W, McKenney, J, Schrott, H, Lewin, A, Shah, S, Sidisin, M, Cho, M, Kush, D & Mitchel, Y 2004, American Journal of Cardiology, vol 93, no. 12, pp. 1481-1486. DOI:

Efficacy of extended-release niacin with lovastatin for hypercholesterolemia: Assessing all reasonable doses with innovative surface graph analysis
Insull, W, McGovern, ME, Schrott, H, Thompson, P, Crouse, JR, Zieve, F & Corbelli, J 2004, Archives of Internal Medicine, vol 164, no. 10, pp. 1121-1127. DOI:

Efficacy and safety of fluvastatin ER 80 mg compared with fluvastatin IR 40 mg in the treatment of primary hypercholesterolaemia
Insull, W, Marais, AD, Aronson, R, Manfreda, S, Bedard, J, Bowman, S, Browne, H, Burgess, LJ, Carr, A, Corn, LG, Craig, IH, Cross, D, El Hafi, S, Elliot, TG, Firth, J, Isaacsohn, JL, Jones, CA, Karcier, S, LeLevier, J, Lipetz, RS, Lohrbauer, LA, Oberman, A, OBrien, R, Poling, TL, Rajput, MC, Richard, CJ, Scott, R, Kes, S, Smith, DK, Soydan, I, Terblanche, J & Wolmarans, K 2004, British Journal of Cardiology, vol 11, no. 2, pp. 148-155.