Timothy B. Boone, MD, PhD

Chair & Program Director, Continence, Pelvic Reconstructive Surgery, & Neurourology Residency, Department of Urology
Co-Director, Professor of Urology, Institute for Academic Medicine
Full Member, Research Institute
Director, Regenerative Medicine Program
Houston Methodist
Weill Cornell Medical College


Dr. Timothy B. Boone is the Chair of the Urology Department, Co-Director of the Institute for Academic Medicine and a member of the Neurological Institute at Houston Methodist Hospital. He is Professor of Urology at Weill Cornell Medical College and holds appointments as Professor of Urology at Texas A&M College of Medicine and Baylor College of Medicine where he is a Clinical Professor of Urology. In 2014, Dr. Boone was appointed Vice Dean, Texas A&M University College of Medicine at the Houston campus.
Dr. Boone earned his Master of Science in physiology and Ph.D. in neuroscience at the University of Texas Graduate School of Biomedical Sciences at Houston. He completed his M.D./Ph.D. at the University of Texas Medical School at Houston and urology residency training at the University of Texas Southwestern Medical School in Dallas. In 1991 he joined the faculty in the Department of Urology at UT Southwestern for two years and then moved to Baylor College of Medicine where he joined the Scott Department of Urology. In 2000 Dr. Boone was named Professor and Chair of the Scott Department of Urology where he served until 2008. For over 20 years he has actively participated in the care of spinal cord injured veterans with neurogenic bladder dysfunction at the VA Spinal Cord Injury Unit in Dallas and in Houston.
Boone specializes in the treatment of patients with incontinence following prostatectomy, women with complex voiding disorders, and bladder problems related to neurologic disease including spinal cord injury, stroke, multiple sclerosis, and Parkinson's disease. He maintains active participation in research, focusing on mechanisms of sensory control and dysfunction in the bladder and urethra that are related to spinal cord injury, diabetes or obstruction. Dr. Boone is the Primary Investigator for the Neuroregeneration and Bladder Sensory Science Laboratory at the Houston Methodist Research Institute.
Throughout his career Dr. Boone has written over 100 publications and given hundreds of lectures regionally and nationally while serving as a visiting professor for many departments of urology. He is a member of the American Association of Genitourinary Surgeons, Clinical Society of GU Surgeons, American Urological Association, Texas Urological Society, Society for Neuroscience, Society for Urodynamics, Female Pelvic Medicine and Urogenital Reconstruction, and the AOA Honor Medical Society. He serves as consultant reviewer for several scientific journals including Neurourology and Urodynamics, Journal of Urology, British Journal of Urology, Urology, Spinal Cord, and the New England Journal of Medicine. He is on the editorial board of Nature Reviews in Urology. Dr. Boone was elected as a Trustee to the American Board of Urology in 2006 and served as President of the American Board of Urology from 2011 - 2012.

Description of Research

Incontinence, Neurourology, Neurogenic Bladder, Urinary Diversion and Urinary Reconstruction

Areas Of Expertise

Incontinence Neurourology Neurogenic Bladder Regenerative Medicine Urinary Diversion and Urinary Reconstruction
Education & Training

, UT Southwestern Medical Center
, The University of Texas Health Science Center at Houston
, University of Texas Graduate School of Biomedical Science - Houston
, University of Texas at Houston Medical School

How to Decide Whether an Artificial Urinary Sphincter or a Male Sling is Best for Male Stress Urinary Incontinence
Boone, TB 2016, Journal of Urology, vol 196, no. 3, pp. 641-2. DOI:

Functional mapping of the pelvic floor and sphincter muscles from high-density surface EMG recordings
Peng, Y, He, J, Khavari, R, Boone, TB & Zhang, Y 2016, International Urogynecology Journal and Pelvic Floor Dysfunction, pp. 1-8. DOI:

Antibody-mediated inhibition of Nogo-A signaling promotes neurite growth in PC-12 cells
Yazdi, IK, Taghipour, N, Hmaidan, S, Palomba, R, Scaria, S, Munoz, A, Boone, TB & Tasciotti, E 2016, Journal of Tissue Engineering, vol 7, pp. 1-9. DOI:

Bladder dysfunction in 2015: Novel findings continue to challenge researchers and clinicians
Khavari, R & Boone, T 2016, Nature Reviews Urology, vol 13, no. 2, pp. 69-70. DOI:

Pelvic organ prolapse in female patients presenting to transitional urology care clinic
Khavari, R, Tokaz, MC, Stewart, JN & Boone, TB 2015, Journal of Urology, vol 194, no. 6, pp. 1654-1658. DOI:

Solifenacin and Tamsulosin Combination Therapy Decreases Urine Nerve Growth Factor/Creatinine Levels in Men
Chan, R, Munoz, A, Wenker, EP, Whipple, M, Miles, B & Boone, TB 2015, Urology. DOI:

The single-incision sling to treat female stress urinary incontinence: A dynamic computational study of outcomes and risk factors
Peng, Y, Khavari, R, Nakib, NA, Stewart, JN, Boone, TB & Zhang, Y 2015, Journal of Biomechanical Engineering, vol 137, no. 9, 91007. DOI:

Inhibition of urothelial P2X3 receptors prevents desensitization of purinergic detrusor contractions in the rat bladder
Ferguson, AC, Sutton, BW, Boone, TB, Ford, AP & Munoz, A 2015, BJU International, vol 116, no. 2, pp. 293-301. DOI:

Imaging: CNS changes in interstitial cystitis/painful bladder syndrome
Khavari, R & Boone, T 2015, Nature Reviews Urology, vol 12, no. 7, pp. 365-366. DOI:

Revision Techniques after Artificial Urinary Sphincter Failure in Men: Results from a Multicenter Study
Eswara, JR, Chan, R, Vetter, JM, Lai, HH, Boone, TB & Brandes, SB 2015, Urology, vol 86, no. 1, pp. 176-180. DOI:

Functional brain interactions during reflexive micturition are absent from spinal cord injured rats with neurogenic bladder
Wong, K , Boone, TB , Wong, STC & Munoz, A 2015, Neurourology and Urodynamics, vol 34, no. 5, pp. 469-474. DOI:

The association of urinary nerve growth factor levels with bladder outlet obstruction in women
Chan, R, Munoz, A, Wenker, EP, Stewart, J, Boone, T & Khavari, R 2015, Female Pelvic Medicine and Reconstructive Surgery, vol 21, no. 2, pp. 111-115. DOI:

The fate of transitional urology patients referred to a tertiary transitional care center
Chan, R, Scovell, J, Jeng, Z, Rajanahally, S, Boone, T & Khavari, R 2014, Urology, vol 84, no. 6, pp. 1544-1548. DOI:

Functional magnetic resonance imaging during urodynamic testing identifies brain structures initiating micturition
Shy, M, Fung, S, Boone, TB, Karmonik, C, Fletcher, SG & Khavari, R 2014, Journal of Urology, vol 192, no. 4, pp. 1149-1154. DOI:

Editorial Comment
Boone, TB 2014, Urology, vol 83, no. 4, pp. 886-887. DOI:

The Contemporary Indications for Augmentation Cystoplasty
Stewart, JN & Boone, TB 2013, Current Bladder Dysfunction Reports, vol 8, no. 4, pp. 326-331. DOI:

North American consensus document on infection of penile prostheses
Darouiche, RO, Bella, AJ, Boone, TB, Brock, G, Broderick, GA, Burnett, AL, Carrion, R, Carson, C, Christine, B, Dhabuwala, CB, Hakim, LS, Henry, G, Jones, LA, Khera, M, Montague, DK & Nehra, A 2013, Urology, vol 82, no. 4, pp. 937-942. DOI:

Diabetic plasticity of non-adrenergic non-cholinergic and P2X-mediated rat bladder contractions
Munoz, A , Boone, TB, Smith, CP & Somogyi, GT 2013, Brain Research Bulletin, vol 95, pp. 40-45. DOI:

The surgical learning curve of artificial urinary sphincter implantation: Implications for prosthetic training and referral
Lai, HH & Boone, TB 2013, Journal of Urology, vol 189, no. 4, pp. 1437-1442. DOI:

Transurethral resection versus intermittent catheterization in patients with retention after combined brachytherapy/external beam radiotherapy for prostate cancer: Intermittent catheterization
Boone, TB 2013, Journal of Urology, vol 189, no. 3, pp. 801-802. DOI: