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Sheldon Kaplan, MD

Full Affiliate Member, Research Institute
Houston Methodist


Biography

After completing his postdoctoral training in 1977, Dr. Kaplan joined the faculty at the Baylor College of Medicine in Houston, Texas as an Assistant Professor in the Department of Pediatrics. He became the chief of the Infectious Disease Service at the Texas Children’s Hospital in 1981, and a full professor at Baylor in 1987. Dr. Kaplan holds several leadership positions in the Department of Pediatrics at Baylor including Professor and Vice Chairman for Clinical Affairs and head of the Pediatric Infectious Diseases Section.

Description of Research

Dr. Kaplan conducts clinical surveillance studies of invasive infections in children. He is also sequencing the predominant clone of community-acquired methicillin-resistant S. aureus (MRSA) in Houston (USA300-HOU) to discover S. aureus epitopes for potential vaccine candidates.

Areas Of Expertise

Infectious diseases S. pneumoniae N. meningitides S. aureus Gene sequencing
Publications

Pneumococcal pneumonia requiring hospitalization in US children in the 13-valent pneumococcal conjugate vaccine era
Olarte, L, Barson, WJ, Barson, RM, Romero, JR, Bradley, JS, Tan, TQ, Givner, LB, Hoffman, JA, Lin, PL, Hultén, KG, Mason, EO & Kaplan, SL 2017, Clinical Infectious Diseases, vol 64, no. 12, pp. 1699-1704. DOI:

Staphylococcus aureus Central Nervous System Infections in Children
Vallejo, JG, Cain, AN, Mason, EO, Kaplan, SL & Hultén, KG 2017, Pediatric Infectious Disease Journal. DOI:

Emergence of multidrug-resistant pneumococcal serotype 35B among children in the United States
Olarte, L, Kaplan, SL, Barson, WJ, Romero, JR, Lin, PL, Tan, TQ, Hoffman, JA, Bradley, JS, Givner, LB, Mason, EO & Hultén, KG 2017, Journal of Clinical Microbiology, vol 55, no. 3, pp. 724-734. DOI:

The Contemporary Microbiology and Rates of Concomitant Osteomyelitis in Acute Septic Arthritis
Branson, J, Vallejo, JG, Flores, AR, Hulten, KG, Mason, EO, Kaplan, SL & McNeil, CC 2016, Pediatric Infectious Disease Journal. DOI:

A randomized, prospective study of pediatric patients with community-acquired pneumonia treated with ceftaroline versus ceftriaxone
Cannavino, CR, Nemeth, A, Korczowski, B, Bradley, JS, ONeal, T, Jandourek, A, Friedland, HD & Kaplan, SL 2016, Pediatric Infectious Disease Journal, vol 35, no. 7, pp. 752-759. DOI:

An Hepatic Abscess in a Patient with Sickle Cell Anemia
Marolf, MD, Chaudhary, M & Kaplan, SL 2016, Pediatric Infectious Disease Journal. DOI:

Role of operative or interventional radiology-guided cultures for osteomyelitis
McNeil, JC, Forbes, AR, Vallejo, JG, Flores, AR, Hultén, KG, Mason, EO & Kaplan, SL 2016, Pediatrics, vol 137, no. 5, e20154616. DOI:

Staphylococcus aureus infections in children: The implications of changing trends
Kaplan, SL 2016, Pediatrics, vol 137, no. 4. DOI:

Healthcare-associated Staphylococcus aureus bacteremia in children: Evidence for reverse vancomycin creep and impact of vancomycin trough values on outcome
McNeil, JC, Kok, EY, Forbes, AR, Lamberth, L, Hulten, KG, Vallejo, JG, Mason, EO & Kaplan, SL 2016, Pediatric Infectious Disease Journal, vol 35, no. 3, pp. 263-268. DOI:

Clinical and molecular features of decreased chlorhexidine susceptibility among nosocomial Staphylococcus aureus isolates at Texas Children's Hospital
McNeil, JC, Kok, EY, Vallejo, JG, Campbell, JR, Hulten, KG, Mason, EO & Kaplan, SL 2016, Antimicrobial Agents and Chemotherapy, vol 60, no. 2, pp. 1121-1128. DOI:

Invasive pneumococcal infections in children following transplantation in the pneumococcal conjugate vaccine era
Olarte, L, Lin, PL, Barson, WJ, Romero, JR, Tan, TQ, Givner, LB, Hoffman, JA, Bradley, JS, Hultén, KG, Mason, EO & Kaplan, SL 2017, Transplant Infectious Disease. DOI:

Characterization of Staphylococcus aureus infections in children with Down syndrome
Johnston, JN, Kaplan, SL, Mason, EO & Hulten, KG 2015, Journal of Infection and Chemotherapy, vol 21, no. 11, pp. 790-794. DOI:

Fever and reversible laboratory abnormalities associated with prolonged use of piperacillin-tazobactam in children
Patel, A, Mao, KR, Mcneil, JC, Kaplan, SL & Vallejo, JG 2015, Pediatric Infectious Disease Journal, vol 34, no. 8, pp. 849-850. DOI:

Multicenter surveillance of streptococcus pneumoniae isolates from middle ear and mastoid cultures in the 13-valent pneumococcal conjugate vaccine era
Kaplan, SL, Center, KJ, Barson, WJ, Ling-Lin, P, Romero, JR, Bradley, JS, Tan, TQ, Hoffman, JA, Peters, TR, Gurtman, A, Scott, DA, Trammel, J, Gruber, WC, Hulten, KG & Mason, EO 2015, Clinical Infectious Diseases, vol 60, no. 9, pp. 1339-1345. DOI:

Staphylococcus aureus retropharyngeal abscess in children
Brown, NK, Hulten, KG, Mason, EO & Kaplan, SL 2015, Pediatric Infectious Disease Journal, vol 34, no. 4, pp. 454-456. DOI:

Streptococcus gallolyticus subsp. pasteurianus infection in twin infants
Hede, SV, Olarte, L, Chandramohan, L, Kaplan, SL & Hulten, KG 2015, Journal of Clinical Microbiology, vol 53, no. 4, pp. 1419-1422. DOI:

Staphylococcus aureus infections among children receiving a solid organ transplant: Clinical features, epidemiology, and antimicrobial susceptibility
Mcneil, JC, Munoz, FM, Hultén, KG, Mason, EO & Kaplan, SL 2015, Transplant Infectious Disease, vol 17, no. 1, pp. 39-47. DOI:

Impact of the 13-valent pneumococcal conjugate vaccine on pneumococcal meningitis in us children
Olarte, L, Barson, WJ, Barson, RM, Lin, PL, Romero, JR, Tan, TQ, Givner, LB, Bradley, JS, Hoffman, JA, Hultén, KG, Mason, EO & Kaplan, SL 2015, Clinical Infectious Diseases, vol 61, no. 5, pp. 767-775. DOI:

Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the infectious diseases society of America
Stevens, DL, Bisno, AL, Chambers, HF, Dellinger, EP, Goldstein, EJC, Gorbach, SL, Hirschmann, JV, Kaplan, SL, Montoya, JG & Wade, JC 2014, Clinical Infectious Diseases, vol 59, no. 2, pp. 147-159. DOI:

Practice guidelines for the diagnosis and management of skin and soft tissue infections: 2014 update by the Infectious Diseases Society of America
Stevens, DL, Bisno, AL, Chambers, HF, Dellinger, EP, Goldstein, EJC, Gorbach, SL, Hirschmann, JV, Kaplan, SL, Montoya, JG, Wade, JC & Infectious Diseases Society of America, DSOA 2014, Clinical Infectious Diseases, vol 59, no. 2, pp. e10-e52. DOI: