Robert G. Grossman, MD

Robert G. Grossman Chair in Neurosurgery, Department of Neurosurgery
Professor of Neurosurgery, Institute for Academic Medicine
Full Clinical Member, Research Institute
Houston Methodist
Weill Cornell Medical College


Research Lab


Biography

Robert G. Grossman, M.D. is the co-founder and director of the Houston Methodist Neurological Institute and chair of the neurosurgical service at Houston Methodist Hospital. He is internationally known for his contributions to advancing the treatment of head and spinal cord injuries, Parkinson's disease, dystonia and epilepsy.

Dr. Grossman received his M.D. from Columbia University College of Physicians and Surgeons, where he was awarded the Borden Undergraduate Research Award in Medicine. He took his surgical internship at Strong Memorial Hospital University of Rochester. He served in the United States Army at the Walter Reed Army Institute of Research in Washington D.C. His postgraduate training in neurosurgery was at the Neurological Institute of New York Presbyterian Hospital-Columbia University.

Dr. Grossman has held academic appointments at the University of Texas Southwestern Medical School and Parkland Hospital in Dallas, at the Albert Einstein College of Medicine, and at the University of Texas Medical Branch in Galveston, where he was Chief of the Division of Neurosurgery. Dr. Grossman and Dr. Kemp Clark were the two neurosurgeons at Parkland Hospital who examined President Kennedy in Trauma Room #1.

Description of Research

Dr. Grossman's research has received recognition by the National Head Injury Foundation, which awarded him the Caveness Award in 1992, and by the Society of Neurological Surgeons, which in 1988 awarded him the Albert and Ellen Grass Foundation prize and medal for continuous commitment to research in the neurosciences by a neurological surgeon. In 2002, he received the Distinguished Service Award of the Society of Neurological Surgeons. In April, 2007, he received the Cushing Medal from the American Association of Neurological Surgeons for outstanding leadership, dedication and contributions to the field of Neurosurgery.

Dr. Grossman is the co-author of Neurobehavioral Consequences of Head Injury (1982), co-author of Medical Neurobiology, Mosby, St. Louis, in its third edition, co-editor with Christopher Loftus of Principles of Neurosurgery, in its second edition (1999), and co-editor of Pallidal Surgery for the Treatment of Parkinson’s Disease and Movement Disorders (1998).

He served on numerous public advisory boards within the United States Public Health Service. He was Chairman of the Board of Scientific Counselors of the National Institute of Neurological Disorders and Stroke (NINDS) from 1991-1993, and a member of the National Advisory Council (NINDS) from 1993-1996. Dr. Grossman was a Director of the American Board of Neurological Surgery from 1984 to 1990, and was Chairman of the Board from 1989 to 1990. He is currently a member of the Advisory Council of the Board. He was the President of the American Epilepsy Society, and of the Society of University Neurosurgeons, and was president of the Society of Neurological Surgeons from 1994-1995. He served on the Editorial Board of the Journal of Neurosurgery from 1979-1989, and was Chairman of the Board from 1987-1989.

Areas Of Expertise

Epilepsy Head injury Neurosurgery
Education & Training

Residency , Columbia Presbyterian Medical Center
Internship , University of Rochester
MD , Columbia University
Publications

Spine injuries sustained by U.S. military personnel in combat are different from non-combat spine injuries
Szuflita, NS, Neal, CJ, Rosner, MK, Frankowski, RF & Grossman, RG 2016, Military Medicine, vol 181, no. 10, pp. 1314-1323. DOI:

Three-dimensional printing of anatomically accurate, patient specific intracranial aneurysm models
Anderson, JR, Thompson, WL, Alkattan, AK, Diaz, O, Klucznik, R, Zhang, YJ, Britz, GW, Grossman, RG & Karmonik, C 2016, Journal of NeuroInterventional Surgery, vol 8, no. 5, pp. 517-520. DOI:

Erratum: Die AOSpine-Klassifikation thorakolumbaler Wirbelsäulenverletzungen (Zeitschrift fur Orthopadie und Unfallchirurgie (2016) 154 (35-42) DOI: 10.1055/s-0041-108266)
Kandziora, F, Schleicher, P, Schnake, KJ, Reinhold, M, Aarabi, B, Bellabarba, C, Chapman, J, Dvorak, M, Fehlings, M, Grossman, R, Kepler, CK, Öner, C, Shanmuganathan, R, Vialle, LR & Vaccaro, AR 2016, Zeitschrift fur Orthopadie und Unfallchirurgie, vol 154, no. 2, pp. 192-194. DOI:

Design and optimization of an EEG-based brain machine interface (BMI) to an upper-limb exoskeleton for stroke survivors
Bhagat, NA, Venkatakrishnan, A, Abibullaev, B, Artz, EJ, Yozbatiran, N, Blank, AA, French, J, Karmonik, C, Grossman, RG, OMalley, MK, Francisco, GE & Contreras-Vidal, JL 2016, Frontiers in Neuroscience, vol 10, no. MAR, 122. DOI:

Globus pallidus internus neuronal activity: a comparative study of linear and non-linear features in patients with dystonia or Parkinson’s disease
Alam, M, Sanghera, MK, Schwabe, K, Lütjens, G, Jin, X, Song, J, von Wrangel, C, Stewart, RM, Jankovic, J, Grossman, RG, Darbin, O & Krauss, JK 2016, Journal of Neural Transmission, vol 123, no. 3, pp. 231-240. DOI:

A robust adaptive denoising framework for real-time artifact removal in scalp EEG measurements
Kilicarslan, A, Grossman, RG & Contreras-Vidal, JL 2016, Journal of Neural Engineering, vol 13, no. 2, 026013. DOI:

Die AOSpine-Klassifikation thorakolumbaler Wirbelsäulenverletzungen
Kandziora, F, Schleicher, P, Schnake, KJ, Reinhold, M, Aarabi, B, Bellabarba, C, Chapman, J, Dvorak, M, Fehlings, M, Grossman, R, Kepler, CK, Öner, C, Shanmuganathan, R, Vialle, LR & Vaccaro, AR 2016, Zeitschrift fur Orthopadie und Unfallchirurgie, vol 154, no. 1, pp. 35-42. DOI:

EEG Source Imaging Guided by Spatiotemporal Specific fMRI: Toward an Understanding of Dynamic Cognitive Processes
Nguyen, T, Potter, T, Nguyen, T, Karmonik, C, Grossman, R & Zhang, Y 2016, Neural Plasticity, vol 2016, 4182483. DOI:

Epilepsy in Historical Figures
Grossman, RG 2016, World Neurosurgery. DOI:

The effect of SOM size and similarity measure on identification of functional and anatomical regions in fMRI data
O’Driscoll, P, Merényi, E, Karmonik, C & Grossman, R 2016, . in Advances in Intelligent Systems and Computing. vol. 428, Advances in Intelligent Systems and Computing, vol. 428, Springer Verlag, pp. 251-263, 11th International on Advances in Self-Organizing Maps and Learning Vector Quantization Workshop, WSOM 2016, Houston, United States, 6-8 January. DOI:

Rationale, design and critical end points for the Riluzole in Acute Spinal Cord Injury Study (RISCIS): A randomized, double-blinded, placebo-controlled parallel multi-center trial
Fehlings, MG, Nakashima, H, Nagoshi, N, Chow, DSL, Grossman, RG & Kopjar, B 2016, Spinal Cord, vol 54, no. 1, pp. 8-15. DOI:

Relationships and redundancies of selected hemodynamic and structural parameters for characterizing virtual treatment of cerebral aneurysms with flow diverter devices
Karmonik, C, Anderson, JR, Beilner, J, Ge, JJ, Partovi, S, Klucznik, RP, Diaz, O, Zhang, YJ, Britz, GW, Grossman, RG, Lv, N & Huang, Q 2015, Journal of Biomechanics. DOI:

Quantification of velocity reduction after flow diverter placement in intracranial aneurysm: An ex vivo study with 3D printed replicas
Anderson, JR, Klucznik, R, Diaz, O, Zhang, YJ, Britz, GW, Grossman, RG & Karmonik, C 2015, . in Proceedings of the Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBS. vol. 2015-November, 7320077, IEEE, pp. 7300-7303, 37th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2015, Milan, Italy, 25-29 August. DOI:

EEG source localization constrained by time varying fMRI
Nguyen, T, Potter, T, Karmonik, C, Grossman, R & Zhang, Y 2015, . in Engineering in Medicine and Biology Society (EMBC). vol. 2015, pp. 630-3, 2015 37th Annual International Conference of the IEEE, Milan, Italy, 25-29 August. DOI:

Quantitative comparison of hemodynamic parameters from steady and transient CFD simulations in cerebral aneurysms with focus on the aneurysm ostium
Karmonik, C , Diaz, O , Klucznik, R , Grossman, RG , Zhang, YJ , Britz, G, Lv, N & Huang, Q 2015, Journal of NeuroInterventional Surgery, vol 7, no. 5, pp. 367-372. DOI:

Validation of computational fluid dynamics methods with anatomically exact, 3D printed MRI phantoms and 4D pcMRI
Anderson, JR, Diaz, O, Klucznik, R, Zhang, YJ, Britz, GW, Grossman, RG, Lv, N, Huang, Q & Karmonik, C 2014, . in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014., 6945165, IEEE, pp. 6699-6701, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Chicago, United States, 26-30 August. DOI:

SOM and MCODE methods of defining functional clusters in MRI of the brain
ODriscoll, P, Merenyi, E, Karmonik, C & Grossman, R 2014, . in 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014., 6943695, IEEE, pp. 734-737, 2014 36th Annual International Conference of the IEEE Engineering in Medicine and Biology Society, EMBC 2014, Chicago, United States, 26-30 August. DOI:

Defining age-related differences in outcome after traumatic spinal cord injury: Analysis of a combined, multicenter dataset
Wilson, JR, Davis, AM, Kulkarni, AV, Kiss, A, Frankowski, RF, Grossman, RG & Fehlings, MG 2014, Spine Journal, vol 14, no. 7, pp. 1192-1198. DOI:

Magnetic resonance imaging as a tool to assess reliability in simulating hemodynamics in cerebral aneurysms with a dedicated computational fluid dynamics prototype: preliminary results
Karmonik, C , Zhang, YJ , Diaz, O , Klucznik, R, Partovi, S, Grossman, RG & Britz, GW 2014, Cardiovascular diagnosis and therapy, vol 4, no. 2, pp. 207-12. DOI:

A prospective, multicenter, Phase i matched-comparison group trial of safety, pharmacokinetics, and preliminary efficacy of riluzole in patients with traumatic spinal cord injury
Grossman, RG, Fehlings, MG, Frankowski, RF, Burau, KD, Chow, DSL, Tator, C, Teng, A, Toups, EG, Harrop, JS, Aarabi, B, Shaffrey, CI, Johnson, MM, Harkema, SJ, Boakye, M, Guest, JD & Wilson, JR 2014, Journal of Neurotrauma, vol 31, no. 3, pp. 239-255. DOI: