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Rita Serda,

Houston Methodist


Areas Of Expertise

Cancer nanovaccines Nano-therapeutics targeting Cellular trafficking
Publications

A recellularized human colon model identifies cancer driver genes
Chen, HJ, Wei, Z, Sun, J, Bhattacharya, A, Savage, DJ, Serda, R, Mackeyev, Y, Curley, SA, Bu, P, Wang, L, Chen, S, Cohen-Gould, L, Huang, E, Shen, X, Lipkin, SM, Copeland, NG, Jenkins, NA & Shuler, ML 2016, Nature Biotechnology, vol 34, no. 8, pp. 845-851. DOI:

A specifically designed nanoconstruct associates, internalizes, traffics in cardiovascular cells, and accumulates in failing myocardium: A new strategy for heart failure diagnostics and therapeutics
Ruiz-Esparza, GU, Segura-Ibarra, V, Cordero-Reyes, AM, Youker, KA, Serda, RE, Cruz-Solbes, AS, Amione-Guerra, J, Yokoi, K, Kirui, DK, Cara, FE, Paez-Mayorga, J, Flores-Arredondo, JH, Guerrero-Beltrán, CE, Garcia-Rivas, G, Ferrari, M, Blanco, E & Torre-Amione, G 2016, European Journal of Heart Failure, vol 18, no. 2, pp. 169-178. DOI:

Reduced cationic nanoparticle cytotoxicity based on serum masking of surface potential
McConnell, KI, Shamsudeen, S, Meraz, IM, Mahadevan, TS, Ziemys, A, Rees, P, Summers, HD & Serda, RE 2016, Journal of Biomedical Nanotechnology, vol 12, no. 1, pp. 154-164. DOI:

A multi-scale FE model for convective-diffusive drug transport within tumor and large vascular networks
Kojic, M, Milosevic, M, Kojic, N, Starosolski, Z, Ghaghada, K, Serda, R, Annapragada, A, Ferrari, M & Ziemys, A 2015, Computer Methods in Applied Mechanics and Engineering, vol 294, pp. 100-122. DOI:

A new imaging platform for visualizing biological effects of non-invasive radiofrequency electric-field cancer hyperthermia
Corr, SJ, Shamsudeen, S, Vergara, LA, Chak-Shing Ho, J, Ware, MJ, Keshishian, V, Yokoi, K, Savage, DJ, Meraz, IM, Kaluarachchi, W, Cisneros, BT, Raoof, M, Nguyen, DT, Zhang, Y, Wilson, LJ, Summers, H, Rees, P, Curley, SA & Serda, RE 2015, PLoS ONE, vol 10, no. 8, e0136382. DOI:

Silencing of tumor necrosis factor receptor-1 in human lung microvascular endothelial cells using particle platforms for siRNA delivery
Bai, L, Andersson, HA, McConnell, KI, Chan, DL, Hernandez, M, Gonzalez, J, Liu, X, Francesca, SL, Sakamoto, JH & Serda, RE 2015, Current Drug Targets, vol 16, no. 13, A013, pp. 1531-1539.

Silencing of tumor necrosis factor receptor-1 in human lung microvascular endothelial cells using particle platforms for siRNA delivery
Bai, L, Andersson, HA, McConnell, KI, Chan, DL, Hernandez, M, Gonzalez, J, Liu, X, Francesca, SL, Sakamoto, JH & Serda, RE 2015, Current Drug Targets, vol 16, no. 13, A013, pp. 1531-1539.

Enhanced gene delivery in porcine vasculature tissue following incorporation of adeno-associated virus nanoparticles into porous silicon microparticles
McConnell, KI, Rhudy, J, Yokoi, K, Gu, J, Mack, A, Suh, J, La Francesca, S, Sakamoto, J & Serda, RE 2014, Journal of Controlled Release, vol 194, pp. 113-121. DOI:

Adjuvant cationic liposomes presenting MPL and IL-12 induce cell death, suppress tumor growth, and alter the cellular phenotype of tumors in a murine model of breast cancer
Meraz, IM, Savage, DJ, Segura-Ibarra, V, Li, J, Rhudy, J, Gu, J & Serda, RE 2014, Molecular Pharmaceutics, vol 11, no. 10, pp. 3484-3491. DOI:

Analysis of the influence of cell heterogeneity on nanoparticle dose response
Ware, MJ, Godin, B, Singh, N, Majithia, R, Shamsudeen, S, Serda, RE, Meissner, KE, Rees, P & Summers, HD 2014, ACS Nano, vol 8, no. 7, pp. 6693-6700. DOI:

Multivalent presentation of MPL by porous silicon microparticles favors T helper 1 polarization enhancing the anti-tumor efficacy of doxorubicin nanoliposomes
Meraz, I, Hearnden, CH, Liu, X, Yang, M, Williams, L, Savage, DJ, Gu, J, Rhudy, JR, Yokoi, K, Lavelle, EC & Serda, RE 2014, PLoS ONE, vol 9, no. 4, e94703. DOI:

HSP70 promoter-driven activation of gene expression for immunotherapy using gold nanorods and near infrared light
Andersson, HA, Kim, Y-S, ONeill, BE, Shi, Z-Z & Serda, RE 2014, Vaccines, vol 2, no. 2, pp. 216-27. DOI:

Characterization of Free and Porous Silicon-Encapsulated Superparamagnetic Iron Oxide Nanoparticles as Platforms for the Development of Theranostic Vaccines
Lundquist, CM, Loo, C, Meraz, IM, Cerda, JDL, Liu, X & Serda, RE 2014, Medical sciences : open access journal, vol 2, no. 1, pp. 51-69. DOI:

Cellular communication via nanoparticle-transporting biovesicles
Ferrati, S, Mcconnell, KI, Mack, AC, Sirisaengtaksin, N, Diaz, R, Bean, AJ, Ferrari, M & Serda, RE 2014, Nanomedicine, vol 9, no. 5, pp. 581-592. DOI:

Optical tracking of drug release from porous silicon delivery vectors
Tonkin, JA, Shamsudeen, S, Brown, MR, Serda, RE, Rees, P & Summers, HD 2014, IET Optoelectronics, vol 8, no. 2, pp. 113-116. DOI:

Porous silicon-superparamagnetic iron oxide complexes and impact on negative contrast enhancement in mri
Lundquist, CM, Loo, CH, Mack, A, Gu, J, Bankson, JA & Serda, RE 2013, . in ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, NEMB 2013., NEMB2013-93065, ASME 2013 2nd Global Congress on NanoEngineering for Medicine and Biology, NEMB 2013, Boston, MA, United States, 4-6 February. DOI:

Porous silicon advances in drug delivery and immunotherapy
Savage, DJ, Liu, X, Curley, SA, Ferrari, M & Serda, RE 2013, Current Opinion in Pharmacology, vol 13, no. 5, pp. 834-841. DOI:

Biological microniches characterizing pathological lesions. Impact on nanoparticle-based delivery of therapeutics.
Meraz, IM, Segura-Ibarra, V, Leonard, F, Gonzalez, J, Ally, S, Godin, B & Serda, RE 2013, Frontiers of Nanoscience, vol 5, pp. 139-173. DOI:

Particle platforms for cancer immunotherapy
Serda, RE 2013, International Journal of Nanomedicine, vol 8, pp. 1683-1696. DOI:

Diffusion transport of nanoparticles at nanochannel boundaries
Mahadevan, TS, Milosevic, M, Kojic, M, Hussain, F, Kojic, N, Serda, R, Ferrari, M & Ziemys, A 2013, Journal of Nanoparticle Research, vol 15, no. 3, 1477. DOI: