Lillian Gaber, MD

Professor of Pathology and Genomic Medicine, Institute for Academic Medicine
Houston Methodist
Weill Cornell Medical College


Biography

Dr. Gaber received her M.D. degree from the Ain Shams University School of Medicine in Cairo, Egypt in 1976. She then completed residencies in anatomical and clinical pathology at the New England Deaconess Hospital in Boston, Massachusetts, and a fellowship in perinatal obstetrics and gynecology pathology at the Brigham and Women’s Hospital. Dr. Gaber joined the faculty at the University of Memphis in Memphis, Tennessee as an assistant professor in the Department of Pathology in 1987. She became a full professor there in 1998. While at the University of Memphis, Dr. Gaber held many leadership positions including director of the Electron Microscopy and Renal Laboratories, director of the General Histology Laboratories, director of the Special Histology Laboratory in the Department of Pathology, and Chief of Clinical Services for the Department of Pathology. Dr. Gaber joined the Department of Pathology and Genomic Medicine at Houston Methodist in 2005 and received her faculty appointment at the Weill Cornell Medical College in 2010.

Description of Research

Dr. Gaber is board certified in anatomic pathology with a subspecialty interest in nephropathology. Her research focuses on studying donor kidney biopsies at the cellular and molecular levels to determine suitability for transplantation, changes following organ reperfusion, and the efficacy of immunosuppressive therapies.

Education & Training

Clinical Fellowship , Harvard University
Residency , New England Deaconess Hospital
Internship , Washington Hospital Center
MD , Ain Shams University School of Medicine
Publications

Gene Expression in Biopsies of Acute Rejection and Interstitial Fibrosis/Tubular Atrophy Reveals Highly Shared Mechanisms That Correlate With Worse Long-Term Outcomes
Modena, BD, Kurian, SM, Gaber, LW, Waalen, J, Su, AI, Gelbart, T, Mondala, TS, Head, SR, Papp, S, Heilman, R, Friedewald, JJ, Flechner, SM, Marsh, CL, Sung, RS, Shidban, H, Chan, L, Abecassis, MM & Salomon, DR 2016, American Journal of Transplantation, vol 16, no. 7, pp. 1982-1998. DOI: 10.1111/ajt.13728

Simultaneous Scalp, Skull, Kidney, and Pancreas Transplant from a Single Donor
Selber, JC, Chang, EI, Clemens, MW, Gaber, L, Hanasono, MM, Klebuc, M, Skoracki, RJ, Trask, T, Yu, P & Gaber, AO 2016, Plastic and Reconstructive Surgery, vol 137, no. 6, pp. 1851-1861. DOI: 10.1097/PRS.0000000000002153

Disparate rates of acute rejection and donor-specific antibodies among high-immunologic risk renal transplant subgroups receiving antithymocyte globulin induction
Patel, SJ, Suki, WN, Loucks-DeVos, J, Graviss, EA, Nguyen, DT, Knight, RJ, Kuten, SA, Moore, LW, Teeter, LD, Gaber, LW & Gaber, AO 2016, Transplant International, vol 29, no. 8, pp. 897-908. DOI: 10.1111/tri.12791

Observations on the use of cidofovir for BK virus infection in renal transplantation
Kuten, SA, Patel, SJ, Knight, RJ, Gaber, LW, Devos, JM & Gaber, AO 2015, Transplant Infectious Disease, vol 16, no. 6, pp. 975-983. DOI: 10.1111/tid.12313

Osteocalcin protects against nonalcoholic steatohepatitis in a mouse model of metabolic syndrome
Gupte, AA , Sabek, OM, Fraga, D, Minze, LJ, Nishimoto, SK, Liu, JZ, Afshar, S, Gaber, L, Lyon, CJ, Gaber, AO & Hsueh, WA 2014, Endocrinology, vol 155, no. 12, pp. 4697-4705. DOI: 10.1210/en.2014-1430

Tubulointerstitial nephritis in systemic lupus erythematosus: Innocent bystander or ominous presage
Dhingra, S, Qureshi, R, Abdellatif, A, Gaber, LW & Truong, LD 2014, Histology and Histopathology, vol 29, no. 5, pp. 553-565.

Molecular classifiers for acute kidney transplant rejection in peripheral blood by whole genome gene expression profiling
Kurian, SM, Williams, AN, Gelbart, T, Campbell, D, Mondala, TS, Head, SR, Horvath, S, Gaber, L, Thompson, R, Whisenant, T, Lin, W, Langfelder, P, Robison, EH, Schaffer, RL, Fisher, JS, Friedewald, J, Flechner, SM, Chan, LK, Wiseman, AC, Shidban, H, Mendez, R, Heilman, R, Abecassis, MM, Marsh, CL & Salomon, DR 2014, American Journal of Transplantation, vol 14, no. 5, pp. 1164-1172. DOI: 10.1111/ajt.12671

A surgeons' guide to renal transplant immunopathology, immunology, and immunosuppression
Gaber, LW , Knight, RJ & Patel, SJ 2013, Surgical Clinics of North America, vol 93, no. 6, pp. 1293-1307. DOI: 10.1016/j.suc.2013.09.002

Screening for BK viremia reduces but does not eliminate the risk of BK nephropathy
Knight, RJ , Gaber, LW, Patel, SJ, Devos, JM, Moore, LW & Gaber, AO 2013, Transplantation, vol 96, no. 7. DOI: 10.1097/TP.0b013e3182a68935

Profound nephrotic syndrome in a patient with ovarian teratoma.
Jeroudi, A, Kadikoy, H, Gaber, L, Ramanathan, V, Frome, A, Anwar, N & Abdellatif, A 2013, Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia, vol 24, no. 4, pp. 777-782.

Outcomes of living donor renal transplants with a negative cross-match and pretransplant donor-specific antibody
Knight, RJ, Devos, JM, Patel, SJ, Land, G, Moore, LW, Gaber, L & Gaber, AO 2013, Transplantation Proceedings, vol 45, no. 4, pp. 1399-1401. DOI: 10.1016/j.transproceed.2013.01.027

Screening for BK viremia reduces but does not eliminate the risk of BK nephropathy: A single-center retrospective analysis
Knight, RJ , Gaber, LW, Patel, SJ, Devos, JM, Moore, LW & Gaber, AO 2013, Transplantation, vol 95, no. 7, pp. 949-954. DOI: 10.1097/TP.0b013e31828423cd

Renal cortical necrosis following a colonoscopy
Hammadah, M, Gaber, L & Raghavan, R 2013, Clinical Nephrology, vol 79, no. 1, pp. 67-71. DOI: 10.5414/CN107171

Association of IgG co-deposition with serum levels of galactose-deficient IgA1 in pediatric IgA nephropathy
Eison, TM, Hastings, MC, Moldoveanu, Z, Sanders, JT, Gaber, L, Walker, PD, Lau, KK, Julian, BA, Novak, J & Wyatt, RJ 2012, Clinical Nephrology, vol 78, no. 6, pp. 465-469. DOI: doi=10.5414/CN107423

Donor-specific HLA-DQ antibodies may contribute to poor graft outcome after renal transplantation
Devos, JM, Gaber, AO, Knight, RJ, Land, GA, Suki, WN, Gaber, LW & Patel, SJ 2012, Kidney International, vol 82, no. 5, pp. 598-604. DOI: 10.1038/ki.2012.190

De novo donor specific antibodies and patient outcomes in renal transplantation.
DeVos, JM, Patel, SJ, Burns, KM, Dilioglou, S, Gaber, LW, Knight, RJ, Gaber, AO & Land, GA 2011, Clinical transplants, pp. 351-358.

Guidelines for the diagnosis of antibody-mediated rejection in pancreas allografts-updated Banff grading schema
Drachenberg, CB, Torrealba, JR, Nankivell, BJ, Rangel, EB, Bajema, IM, Kim, DU, Arend, L, Bracamonte, ER, Bromberg, JS, Bruijn, JA, Cantarovich, D, Chapman, JR, Farris, AB, Gaber, L, Goldberg, JC, Haririan, A, Honsová, E, Iskandar, SS, Klassen, DK, Kraus, E, Lower, F, Odorico, J, Olson, JL, Mittalhenkle, A, Munivenkatappa, R, Paraskevas, S, Papadimitriou, JC, Randhawa, P, Reinholt, FP, Renaudin, K, Revelo, P, Ruiz, P, Samaniego, MD, Shapiro, R, Stratta, RJ, Sutherland, DER, Troxell, ML, Voska, L, Seshan, SV, Racusen, LC & Bartlett, ST 2011, American Journal of Transplantation, vol 11, no. 9, pp. 1792-1802. DOI: 10.1111/j.1600-6143.2011.03670.x

YSPSL (rPSGL-Ig) for improvement of early renal allograft function: A double-blind, placebo-controlled, multi-center Phase IIa study
Osama Gaber, A, Mulgaonkar, S, Kahan, BD, Steve Woodle, E, Alloway, R, Bajjoka, I, Jensik, S, Klintmalm, GB, Patton, PR, Wiseman, A, Lipshutz, G, Kupiec-Weglinski, J, Gaber, LW, Katz, E, Irish, W, Squiers, EC & Hemmerich, S 2011, Clinical Transplantation, vol 25, no. 4, pp. 523-533. DOI: 10.1111/j.1399-0012.2010.01295.x

The role of mTOR inhibition in renal transplant immune suppression
Patel, SJ, Dawson, KL, Knight, RJ, Abdellatif, A, Achkar, K, Gaber, LW & Gaber, AO 2011, Dialysis and Transplantation, vol 40, no. 1, pp. 23-29. DOI: 10.1002/dat.20530

Serial analysis of biomarkers of acute pancreas allograft rejection
Cashion, AK, Sabek, O, Driscoll, C, Gaber, L, Tolley, E & Gaber, AO 2010, Clinical Transplantation, vol 24, no. 6. DOI: 10.1111/j.1399-0012.2010.01285.x