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Leif E. Peterson,

Houston Methodist
Weill Cornell Medical College


Areas Of Expertise

Random matrix theory Eigendecomposition Metaheuristics Duo-mining N-grams
Publications

Transcript Analysis for Internal Biodosimetry Using Peripheral Blood from Neuroblastoma Patients Treated with 131I-mIBG, a Targeted Radionuclide
Edmondson, DA, Karski, EE, Kohlgruber, A, Koneru, H, Matthay, KK, Allen, S, Hartmann, CL, Peterson, LE, DuBois, SG & Coleman, MA 2016, Radiation Research, vol 186, no. 3, pp. 235-244. DOI:

Nuclear receptor corepressor 1 expression and output declines with prostate cancer progression
Lopez, SM, Agoulnik, AI, Zhang, M, Peterson, LE, Suarez, E, Gandarillas, GA, Frolov, A, Li, R, Rajapakshe, K, Coarfa, C, Ittmann, MM, Weigel, NL & Agoulnik, IU 2016, Clinical Cancer Research, vol 22, no. 15, pp. 3937-3949. DOI:

Postoperative antimicrobials after lung transplantation and the development of multidrug-resistant bacterial and Clostridium difficile infections: an analysis of 500 non-cystic fibrosis lung transplant patients
Whiddon, AR, Dawson, KL, Fuentes, A, Perez, KK, Peterson, LE & Kaleekal, T 2016, Clinical Transplantation, vol 30, no. 7, pp. 767-773. DOI:

Transcript Analysis for Internal Biodosimetry Using Peripheral Blood from Neuroblastoma Patients Treated with 131I-mIBG, a Targeted Radionuclide
Edmondson, DA, Karski, EE, Kohlgruber, A, Koneru, H, Matthay, KK, Allen, S, Hartmann, CL, Peterson, LE, DuBois, SG & Coleman, MA 2016, Radiation Research, vol 186, no. 3, pp. 235-244. DOI: , 10.1667/RR14263.1

Evaluating biomarkers to model cancer risk post cosmic ray exposure
M. Sridharan, D, Asaithamby, A, Blattnig, S, Costes, S, Doetsch, P, Dynan, W, Hahnfeldt, P, Hlatky, L, Kidane, Y, Kronenberg, A, Naidu, M, Peterson, LE, Plante, I, Ponomarev, A, Saha, J, Snijders, A, Srinivasan, K, Tang, J, Werner, E & Pluth, J 2016, Life Sciences in Space Research, vol 9, 535474, pp. 19-47. DOI:

Optimizing evaluation of patients with low-to-intermediate-risk acute chest pain: A randomized study comparing stress myocardial perfusion tomography incorporating stress-only imaging versus cardiac CT
Nabi, F, Kassi, M, Muhyieddeen, K, Chang, SM, Xu, J, Peterson, L, Wray, N, Shirkey, B, Ashton, C & Mahmarian, J 2016, Journal of Nuclear Medicine, vol 57, no. 3, pp. 378-384. DOI:

Multiple Human Papilloma Virus Infections and Their Impact on the Development of High-Risk Cervical Lesions
Salazar, KL, Zhou, HS, Xu, J, Peterson, LE, Schwartz, MR, Mody, DR & Ge, Y 2015, Acta Cytologica, vol 59, no. 5, pp. 391-398. DOI:

Adjustment of lifetime risks of space radiation-induced cancer by the healthy worker effect and cancer misclassification
Peterson, LE & Kovyrshina, T 2015, Heliyon, vol 1, no. 4, e00048. DOI:

Distribution of Alkaline Phosphatase, Osteopontin, RANK Ligand and Osteoprotegerin in Calcified Human Carotid Atheroma
Higgins, CL, Isbilir, S, Basto, P, Chen, IY, Vaduganathan, M, Vaduganathan, P, Reardon, MJ, Lawrie, G, Peterson, L & Morrisett, JD 2015, Protein Journal, vol 34, no. 5, pp. 315-328. DOI:

Pleiotropic effect of the proton pump inhibitor esomeprazole leading to suppression of lung inflammation and fibrosis
Ghebremariam, YT, Cooke, JP, Gerhart, W, Griego, C, Brower, JB, Doyle-Eisele, M, Moeller, BC, Zhou, Q, Ho, L, de Andrade, J, Raghu, G, Peterson, L, Rivera, A & Rosen, GD 2015, Journal of Translational Medicine, vol 13, no. 1, 249. DOI:

Low-dose radiation affects cardiac physiology: Gene networks and molecular signaling in cardiomyocytes
Coleman, MA, Sasi, SP, Onufrak, J, Natarajan, M, Manickam, K, Schwab, J, Muralidharan, S, Peterson, LE, Alekseyev, YO, Yan, X & Goukassian, DA 2015, American Journal of Physiology - Heart and Circulatory Physiology, vol 309, no. 11, pp. H1947-H1963. DOI:

Regadenoson provides perfusion results comparable to adenosine in heterogeneous patient populations: A quantitative analysis from the ADVANCE MPI trials
Mahmarian, JJ , Peterson, LE , Xu, J, Cerqueira, MD, Iskandrian, AE, Bateman, TM, Thomas, GS & Nabi, F 2014, Journal of Nuclear Cardiology. DOI:

Transcriptome analysis of human adipocytes implicates the NOD-like receptor pathway in obesity-induced adipose inflammation
Yin, Z , Deng, T , Peterson, LE, Yu, R, Lin, J, Hamilton, DJ, Reardon, PR, Sherman, V, Winnier, GE, Zhan, M, Lyon, CJ, Wong, STC & Hsueh, WA 2014, Molecular and Cellular Endocrinology, vol 394, no. 1-2, pp. 80-87. DOI:

Reduction of costs for anemia-management drugs associated with the use of ferric citrate
Thomas, A & Peterson, LE 2014, International Journal of Nephrology and Renovascular Disease, vol 7, pp. 191-200. DOI:

Superresolution MUSIC based on Marcenko-Pastur limit distribution reduces uncertainty and improves DNA gene expression-based microarray classification
Peterson, LE 2014, . in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). vol. 8452 LNBI, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 8452 LNBI, Springer Verlag, pp. 194-209, 10th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2013, Nice, France, 20-22 June. DOI:

Integrating rapid diagnostics and antimicrobial stewardship improves outcomes in patients with antibiotic-resistant Gram-negative bacteremia
Perez, KK , Olsen, RJ, Musick, WL, Cernoch, PL, Davis, JR, Peterson, LE & Musser, JM 2014, Journal of Infection, vol 69, no. 3, pp. 216-225. DOI:

Evolutionary algorithms applied to likelihood function maximization during poisson, logistic, and Cox proportional hazards regression analysis
Peterson, LE 2014, . in Proceedings of the 2014 IEEE Congress on Evolutionary Computation, CEC 2014., 6900660, Institute of Electrical and Electronics Engineers Inc. pp. 1054-1061, 2014 IEEE Congress on Evolutionary Computation, CEC 2014, Beijing, China, 6-11 July. DOI:

Superresolution MUSIC based on Marcenko-Pastur limit distribution reduces uncertainty and improves DNA gene expression-based microarray classification
Peterson, LE 2014, . in Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics). vol. 8452 LNBI, Lecture Notes in Computer Science (including subseries Lecture Notes in Artificial Intelligence and Lecture Notes in Bioinformatics), vol. 8452 LNBI, Springer Verlag, pp. 194-209, 10th International Meeting on Computational Intelligence Methods for Bioinformatics and Biostatistics, CIBB 2013, Nice, France, 20-22 June. DOI:

HLA-restricted NY-ESO-1 peptide immunotherapy for metastatic castration resistant prostate cancer
Sonpavde, G, Wang, M, Peterson, LE, Wang, HY, Joe, T, Mims, MP, Kadmon, D, Ittmann, MM, Wheeler, TM, Gee, AP, Wang, RF & Hayes, TG 2014, Investigational New Drugs, vol 32, no. 2, pp. 235-242. DOI:

Mechanical unloading promotes myocardial energy recovery in human heart failure
Gupte, AA , Hamilton, DJ, Cordero-Reyes, AM, Youker, KA, Yin, Z, Estep, JD, Stevens, RD, Wenner, B, Ilkayeva, O, Loebe, M, Peterson, LE, Lyon, CJ, Wong, STC, Newgard, CB, Torre-Amione, G, Taegtmeyer, H & Hsueh, WA 2014, Circulation: Cardiovascular Genetics, vol 7, no. 3, pp. 266-276. DOI: